Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation

Protective Effects of Bupivacaine against Kainic Acid-Induced Seizure and Neuronal Cell Death in the Rat Hippocampus

(2015) Kuan Ming Chiu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity

(2015) Antoine Larochelle et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study

(2015) Matthew L. Diamond et al.   EPILEPSIA

Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-κB Activation in Microglial Cells

(2015) Dunjing Wang et al.   INFLAMMATION

TLR1 expression in mouse brain was increased in a KA-induced seizure model

(2015) Fa-Xiang Wang et al.   INFLAMMATION RESEARCH

Interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the PI3K/Akt/mTOR signaling pathway in hippocampal neurons

(2015) Zhaohua Xiao et al.   JOURNAL OF NEUROIMMUNOLOGY

A Prosaposin-Derived Peptide Alleviates Kainic Acid-Induced Brain Injury

(2015) Hiroaki Nabeka et al.   PLoS One

Epilepsy and innate immune system: A possible immunogenic predisposition and related therapeutic implications

(2015) Nassim Matin et al.   Human Vaccines & Immunotherapeutics

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia

(2013) Linli Yao et al.   Journal of Neuroinflammation

Acetate supplementation modulates brain histone acetylation and decreases interleukin-1β expression in a rat model of neuroinflammation

(2012) Mahmoud L Soliman et al.   Journal of Neuroinflammation

Synaptic Kainate Receptors in CA1 Interneurons Gate the Threshold of Theta-Frequency-Induced Long-Term Potentiation

(2012) V. R. J. Clarke et al.   JOURNAL OF NEUROSCIENCE

c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus

(2010) Giada Spigolon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice

(2010) Dong Hyun Kim et al.   NEUROPHARMACOLOGY

MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses

(2009) Brett Verstak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner

(2009) X. Wang et al.   JOURNAL OF IMMUNOLOGY

TLR3 and TLR4 are innate antiviral immune receptors in human microglia: Role of IRF3 in modulating antiviral and inflammatory response in the CNS

(2009) Hyeon-Sook Suh et al.   VIROLOGY

The role of cytokines in the pathophysiology of epilepsy

(2008) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats

(2008) Bin Zhang et al.   BRAIN RESEARCH

Toll-like receptors in neurodegeneration

(2008) Eitan Okun et al.   BRAIN RESEARCH REVIEWS

Non-Invasive Tests in Animal Models and Humans: A New Paradigm for Assessing Efficacy of Biologics Including Prebiotics and Probiotics

(2008) R. Butler   CURRENT PHARMACEUTICAL DESIGN

Status Epilepticus Induces a Particular Microglial Activation State Characterized by Enhanced Purinergic Signaling

(2008) E. Avignone et al.   JOURNAL OF NEUROSCIENCE

Glial toll-like receptor signaling in central nervous system infection and autoimmunity

(2007) Pamela A. Carpentier et al.   BRAIN BEHAVIOR AND IMMUNITY

Protective effect of topiramate on kainic acid-induced cell death in mice hippocampus

(2007) Hae Jeong Park et al.   EPILEPSIA