Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro

Hypoxia paradoxically inhibits the angiogenic response of isolated vessel explants while inducing overexpression of vascular endothelial growth factor

(2016) Alfred C. Aplin et al.   ANGIOGENESIS

Loss of PPARγ in endothelial cells leads to impaired angiogenesis

(2016) Sanna Vattulainen-Collanus et al.   JOURNAL OF CELL SCIENCE

RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases

(2016) Adriana O. Santos et al.   PLoS One

HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells

(2016) Tessa D. Nauta et al.   PLoS One

HIF2α signaling inhibits adherens junctional disruption in acute lung injury

(2015) Haixia Gong et al.   JOURNAL OF CLINICAL INVESTIGATION

The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting

(2015) Michael R. Dores et al.   MOLECULAR BIOLOGY OF THE CELL

Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

(2014) Katharina Leithner et al.   BMC CANCER

RalA signaling pathway as a therapeutic target in hepatocellular carcinoma (HCC)

(2014) Mohamad Ezzeldin et al.   Molecular Oncology

Endothelin-1 decreases endothelial PPARγ signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension

(2013) David Wolf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway

(2012) Hai-Xiang Sun et al.   HEPATOLOGY

Upstream Stimulatory Factor 2 and Hypoxia-Inducible Factor 2  (HIF2 ) Cooperatively Activate HIF2 Target Genes during Hypoxia

(2012) M. R. Pawlus et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia-Induced Alternative Splicing in Endothelial Cells

(2012) Julia E. Weigand et al.   PLoS One

Identification of novel transcripts in annotated genomes using RNA-Seq

(2011) A. Roberts et al.   BIOINFORMATICS

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

Opposing Effects of the Angiopoietins on the Thrombin-Induced Permeability of Human Pulmonary Microvascular Endothelial Cells

(2011) Melanie van der Heijden et al.   PLoS One

Concise Review: Neutral Endopeptidase (CD10): A Multifaceted Environment Actor in Stem Cells, Physiological Mechanisms, and Cancer

(2011) Veronique Maguer-Satta et al.   STEM CELLS

Hypoxia Impedes Vasculogenesis of In Vitro Engineered Bone

(2011) Debby Gawlitta et al.   TISSUE ENGINEERING PART A

Improving RNA-Seq expression estimates by correcting for fragment bias

(2011) Adam Roberts et al.   GENOME BIOLOGY

Decreased Neprilysin and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease

(2010) Marilee J. Wick et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

ARRDC3 suppresses breast cancer progression by negatively regulating integrin β4

(2010) K M Draheim et al.   ONCOGENE

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Endothelial deletion of hypoxia-inducible factor-2  (HIF-2 ) alters vascular function and tumor angiogenesis

(2009) N. Skuli et al.   BLOOD

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

The PH-PxxP domain of RalGPS2 promotes PC12 cells differentiation acting as a dominant negative for RalA GTPase activation

(2009) Michela Ceriani et al.   NEUROSCIENCE RESEARCH

The Effect of Hypoxia on In Vitro Prevascularization of a Thick Soft Tissue

(2009) Craig K. Griffith et al.   TISSUE ENGINEERING PART A

PPARγ ligands, rosiglitazone and pioglitazone, inhibit bFGF- and VEGF-mediated angiogenesis

(2008) Ahmad Aljada et al.   ANGIOGENESIS

On the origins of arrestin and rhodopsin

(2008) Carlos E Alvarez   BMC EVOLUTIONARY BIOLOGY

HIF-1α and HIF-2α have divergent roles in colon cancer

(2008) Takaaki Imamura et al.   INTERNATIONAL JOURNAL OF CANCER