Human IFIT proteins inhibit lytic replication of KSHV: A new feed-forward loop in the innate immune system

Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability

(2018) Britney Johnson et al.   IMMUNITY

A Talented Duo: IFIT1 and IFIT3 Patrol Viral RNA Caps

(2018) Youn Jung Choi et al.   IMMUNITY

Continuous DNA replication is required for late gene transcription and maintenance of replication compartments in gammaherpesviruses

(2018) Dajiang Li et al.   PLoS Pathogens

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response

(2017) Mehdi Morchikh et al.   MOLECULAR CELL

Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations

(2017) Yazan M. Abbas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid RNase L–driven arrest of protein synthesis in the dsRNA response without degradation of translation machinery

(2017) Jesse Donovan et al.   RNA

Applications of Phosphate Modification and Labeling to Study (m)RNA Caps

(2017) Marcin Warminski et al.   Topics in Current Chemistry

Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency

(2016) Arunava Roy et al.   JOURNAL OF VIROLOGY

Expansion of the Gene Ontology knowledgebase and resources

(2016)   NUCLEIC ACIDS RESEARCH

Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS

(2016) Guigen Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals

(2016) Matthew D Daugherty et al.   eLife

Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein

(2015) Jian-jun Wu et al.   Cell Host & Microbe

Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses

(2015) Zhe Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An optimized method for high-titer lentivirus preparations without ultracentrifugation

(2015) Wei Jiang et al.   Scientific Reports

Interplay between Kaposi's sarcoma-associated herpesvirus and the innate immune system

(2014) Kevin Brulois et al.   CYTOKINE & GROWTH FACTOR REVIEWS

An Important Role for Mitochondrial Antiviral Signaling Protein in the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle

(2014) J. A. West et al.   JOURNAL OF VIROLOGY

RNase L Targets Distinct Sites in Influenza A Virus RNAs

(2014) Daphne A. Cooper et al.   JOURNAL OF VIROLOGY

Identification of the Physiological Gene Targets of the Essential Lytic Replicative Kaposi's Sarcoma-Associated Herpesvirus ORF57 Protein

(2014) Dinesh Verma et al.   JOURNAL OF VIROLOGY

Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

(2014) Volker Fensterl et al.   JOURNAL OF VIROLOGY

A Viral RNA Structural Element Alters Host Recognition of Nonself RNA

(2014) J. L. Hyde et al.   SCIENCE

Epidemiology and Transmission of Kaposi’s Sarcoma-Associated Herpesvirus

(2014) Veenu Minhas et al.   Viruses-Basel

CTCF and Rad21 Act as Host Cell Restriction Factors for Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Lytic Replication by Modulating Viral Gene Transcription

(2014) Da-Jiang Li et al.   PLoS Pathogens

KSHV 2.0: A Comprehensive Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Genome Using Next-Generation Sequencing Reveals Novel Genomic and Functional Features

(2014) Carolina Arias et al.   PLoS Pathogens

Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells

(2013) M. A. Ansari et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Latency in Endothelial and B Cells Activates Gamma Interferon-Inducible Protein 16-Mediated Inflammasomes

(2013) V. V. Singh et al.   JOURNAL OF VIROLOGY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

(2013) Matthias Habjan et al.   PLoS Pathogens

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms

(2012) Zhenlin Yang et al.   CELL RESEARCH

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

(2012) J. Andrejeva et al.   JOURNAL OF GENERAL VIROLOGY

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

(2012) Kevin F. Brulois et al.   JOURNAL OF VIROLOGY

IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection

(2011) Nagaraj Kerur et al.   Cell Host & Microbe

CRM1 controls the composition of nucleoplasmic pre-snoRNA complexes to licence them for nucleolar transport

(2011) Bérengère Pradet-Balade et al.   EMBO JOURNAL

The many roles of the highly interactive HSV protein ICP27, a key regulator of infection

(2011) Rozanne M Sandri-Goldin   Future Microbiology

Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction

(2011) Jinjong Myoung et al.   JOURNAL OF VIROLOGICAL METHODS

Inhibition of RIG-I-Mediated Signaling by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Deubiquitinase ORF64

(2011) K.-S. Inn et al.   JOURNAL OF VIROLOGY

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Discovery of a Viral NLR Homolog that Inhibits the Inflammasome

(2011) S. M. Gregory et al.   SCIENCE

Human mitochondrial mRNAs—like members of all families, similar but different

(2010) Richard J. Temperley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Activation of Plasmacytoid Dendritic Cells by Kaposi's Sarcoma-Associated Herpesvirus

(2010) J. A. West et al.   JOURNAL OF VIROLOGY

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Viruses know more than one way to don a cap

(2010) Eugene V. Koonin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired interferon signaling is a common immune defect in human cancer

(2009) R. J. Critchley-Thorne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like Receptor 4 Mediates Innate Immunity to Kaposi Sarcoma Herpesvirus

(2008) Dimitrios Lagos et al.   Cell Host & Microbe

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

(2008) Fulvia Terenzi et al.   EMBO JOURNAL

Upregulation of the TLR3 Pathway by Kaposi's Sarcoma-Associated Herpesvirus during Primary Infection

(2008) J. West et al.   JOURNAL OF VIROLOGY