TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection

Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis

(2018) Pietro Fratta et al.   EMBO JOURNAL

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

(2018) Ching-Chieh Chou et al.   NATURE NEUROSCIENCE

Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism

(2018) Erin G Conlon et al.   eLife

Linking hnRNP Function to ALS and FTD Pathology

(2018) Maria D. Purice et al.   Frontiers in Neuroscience

Dysfunctional RNA binding proteins and stress granules in multiple sclerosis

(2018) Hannah E. Salapa et al.   JOURNAL OF NEUROIMMUNOLOGY

Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination

(2018) Jia Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases

(2017) Hong Joo Kim et al.   NEURON

Human Endogenous Retrovirus-K and TDP-43 Expression Bridges ALS and HIV Neuropathology

(2017) Renée N. Douville et al.   Frontiers in Microbiology

Cardiovirus Leader proteins bind exportins: Implications for virus replication and nucleocytoplasmic trafficking inhibition

(2016) Jessica J. Ciomperlik et al.   VIROLOGY

Cytoplasmic translocation, aggregation and cleavage of TDP-43 by enteroviral proteases modulate viral pathogenesis

(2015) G Fung et al.   CELL DEATH AND DIFFERENTIATION

Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis?

(2015) Peter Göttle et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development

(2015) J. Dai et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglial Maturation Is Dependent on Intracellular Protein Shuttling

(2015) P. Gottle et al.   JOURNAL OF NEUROSCIENCE

Three cardiovirus Leader proteins equivalently inhibit four different nucleocytoplasmic trafficking pathways

(2015) Jessica J. Ciomperlik et al.   VIROLOGY

Inflammation Induces TDP-43 Mislocalization and Aggregation

(2015) Ana Sofia Correia et al.   PLoS One

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

(2014) E. L. Scotter et al.   JOURNAL OF CELL SCIENCE

Cytoplasmic RNA Granules and Viral Infection

(2014) Wei-Chih Tsai et al.   Annual Review of Virology

RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum

(2013) Matthew Thomas et al.   BRAIN

New Insights into Functional Roles of the Polypyrimidine Tract-Binding Protein

(2013) Maria Romanelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions

(2012) Marcela Raices et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly

(2011) F. Borghese et al.   JOURNAL OF VIROLOGY

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

(2011) Magdalini Polymenidou et al.   NATURE NEUROSCIENCE

Different Strains of Theiler's Murine Encephalomyelitis Virus Antagonize Different Sites in the Type I Interferon Pathway

(2010) S. Stavrou et al.   JOURNAL OF VIROLOGY

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS

(2010) S.-C. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

(2009) Manuela Neumann et al.   ACTA NEUROPATHOLOGICA

Stress granules

(2009) Paul Anderson et al.   CURRENT BIOLOGY

Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

(2008) Lionel M. Igaz et al.   AMERICAN JOURNAL OF PATHOLOGY

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

(2008) Masato Hasegawa et al.   ANNALS OF NEUROLOGY