Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis?

The Roles of Cdk5-Mediated Subcellular Localization of FOXO1 in Neuronal Death

(2015) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglial Maturation Is Dependent on Intracellular Protein Shuttling

(2015) P. Gottle et al.   JOURNAL OF NEUROSCIENCE

Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination

(2015) Jeffery D Haines et al.   NATURE NEUROSCIENCE

TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells

(2014) R. Calabrese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nuclear Trafficking in Health and Disease

(2014) Amir Mor et al.   CURRENT OPINION IN CELL BIOLOGY

TIP30 inhibits oligodendrocyte precursor cell differentiation via cytoplasmic sequestration of Olig1

(2014) Wenjing Yang et al.   GLIA

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

Dynamics of ten-eleven translocation hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation

(2014) Xianghui Zhao et al.   GLIA

Overexpression of cyclin dependent kinase inhibitor P27/Kip1 increases oligodendrocyte differentiation from induced pluripotent stem cells

(2014) Shinpei Tamaki et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

E2F1 Coregulates Cell Cycle Genes and Chromatin Components during the Transition of Oligodendrocyte Progenitors from Proliferation to Differentiation

(2014) L. Magri et al.   JOURNAL OF NEUROSCIENCE

Effect of OLIG1 on the development of oligodendrocytes and myelination in a neonatal rat PVL model induced by hypoxia-ischemia

(2014) TONGFEI CHENG et al.   Molecular Medicine Reports

Regulation of Myelination in the Central Nervous System by Nuclear Lamin B1 and Non-coding RNAs

(2014) Shu-Ting Lin et al.   Translational Neurodegeneration

Regulation of cell proliferation by nucleocytoplasmic dynamics of postnatal and embryonic exon-II-containing MBP isoforms

(2013) Hande Ozgen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves

(2013) Antonietta Bernardo et al.   BIOLOGICAL CHEMISTRY

Impaired Cytoplasmic-Nuclear Transport of Hypoxia-Inducible Factor-1α in Amyotrophic Lateral Sclerosis

(2013) Yuko Nagara et al.   BRAIN PATHOLOGY

Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation

(2013) Yan Yang et al.   DEVELOPMENTAL BIOLOGY

Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury

(2013) Marie-Krystel Gauthier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Oligodendroglial lineage cells express nuclear p57kip2 in multiple sclerosis lesions

(2013) Sabine Pfeifenbring et al.   GLIA

Upregulation of CRM1 Relates to Neuronal Apoptosis after Traumatic Brain Injury in Adult Rats

(2013) Aihong Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Ascl1/Mash1 Promotes Brain Oligodendrogenesis during Myelination and Remyelination

(2013) H. Nakatani et al.   JOURNAL OF NEUROSCIENCE

Elevated levels of PPAR-gamma in the cerebrospinal fluid of patients with multiple sclerosis

(2013) Levente Szalardy et al.   NEUROSCIENCE LETTERS

Limited TCF7L2 Expression in MS Lesions

(2013) Alexander Lürbke et al.   PLoS One

Primary progressive multiple sclerosis: part of the MS disease spectrum or separate disease entity?

(2012) Jack Antel et al.   ACTA NEUROPATHOLOGICA

p57kip2 regulates glial fate decision in adult neural stem cells

(2012) J. J. Jadasz et al.   DEVELOPMENT

Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation

(2012) Jianqin Niu et al.   GLIA

Therapeutic effects of anti-Delta1 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease

(2012) Sayaka Tsugane et al.   JOURNAL OF NEUROIMMUNOLOGY

Eicosapentaenoic acid (EPA) induces peroxisome proliferator-activated receptors and ameliorates experimental autoimmune encephalomyelitis

(2012) Kiichi Unoda et al.   JOURNAL OF NEUROIMMUNOLOGY

Differential Modulation of the Oligodendrocyte Transcriptome by Sonic Hedgehog and Bone Morphogenetic Protein 4 via Opposing Effects on Histone Acetylation

(2012) M. Wu et al.   JOURNAL OF NEUROSCIENCE

Nucleus-localized 21.5-kDa myelin basic protein promotes oligodendrocyte proliferation and enhances neurite outgrowth in coculture, unlike the plasma membrane-associated 18.5-kDa isoform

(2012) Graham S.T. Smith et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Differential requirement of cyclin-dependent kinase 2 for oligodendrocyte progenitor cell proliferation and differentiation

(2012) Céline Caillava et al.   Cell Division

The complex world of oligodendroglial differentiation inhibitors

(2011) David Kremer et al.   ANNALS OF NEUROLOGY

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells

(2011) H. Wu et al.   GENES & DEVELOPMENT

Olig1 is expressed in human oligodendrocytes during maturation and regeneration

(2011) Ahmad Othman et al.   GLIA

GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo

(2011) Kasum Azim et al.   GLIA

Heterogeneous Nuclear Ribonucleoprotein (hnRNP) F Is a Novel Component of Oligodendroglial RNA Transport Granules Contributing to Regulation of Myelin Basic Protein (MBP) Synthesis

(2011) Robin White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous system

(2011) Céline Caillava et al.   JOURNAL OF CELL BIOLOGY

Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease

(2011) Tz-Chuen Ju et al.   JOURNAL OF CELL BIOLOGY

Protein localization in disease and therapy

(2011) M.-C. Hung et al.   JOURNAL OF CELL SCIENCE

A Cdk5-Dependent Switch Regulates Lis1/Ndel1/Dynein-Driven Organelle Transport in Adult Axons

(2011) J. P. Pandey et al.   JOURNAL OF NEUROSCIENCE

Remyelination Is Altered by Bone Morphogenic Protein Signaling in Demyelinated Lesions

(2011) J. K. Sabo et al.   JOURNAL OF NEUROSCIENCE

Astrocytes from the Contused Spinal Cord Inhibit Oligodendrocyte Differentiation of Adult Oligodendrocyte Precursor Cells by Increasing the Expression of Bone Morphogenetic Proteins

(2011) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions

(2011) X. Pedre et al.   JOURNAL OF NEUROSCIENCE

Classical 18.5-and 21.5-kDa isoforms of myelin basic protein inhibit calcium influx into oligodendroglial cells, in contrast to golli isoforms

(2011) Graham S.T. Smith et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Unknown

(2011) Giuseppe Faraco et al.   MOLECULAR MEDICINE

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Recognition of nuclear targeting signals by Karyopherin-β proteins

(2010) Darui Xu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

(2010) Dorothee Dormann et al.   EMBO JOURNAL

Thapsigargin-induced Ca2+ increase inhibits TGFβ1-mediated Smad2 transcriptional responses via Ca2+/calmodulin-dependent protein kinase II

(2010) Ming Ming et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Focal and diffuse cortical degenerative changes in a marmoset model of multiple sclerosis

(2010) IM Pomeroy et al.   Multiple Sclerosis Journal

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

The QKI-6 RNA Binding Protein Localizes with the MBP mRNAs in Stress Granules of Glial Cells

(2010) Yunling Wang et al.   PLoS One

Differential Subcellular Distributions and Trafficking Functions of hnRNP A2/B1 Spliceoforms

(2010) Siew Ping Han et al.   TRAFFIC

Retinoid X receptors: common heterodimerization partners with distinct functions

(2010) Philippe Lefebvre et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Microtubules govern stress granule mobility and dynamics

(2009) Elena S. Nadezhdina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Two-tier transcriptional control of oligodendrocyte differentiation

(2009) Huiliang Li et al.   CURRENT OPINION IN NEUROBIOLOGY

miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination

(2009) S.-T. Lin et al.   Disease Models & Mechanisms

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Remyelination — An effective means of neuroprotection

(2009) Charlotte C. Bruce et al.   HORMONES AND BEHAVIOR

Chronic expression of PPAR-δ by oligodendrocyte lineage cells in the injured rat spinal cord

(2009) Akshata Almad et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Sending Mixed Signals

(2009) Jill M. See et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Wnt signaling is sufficient to perturb oligodendrocyte maturation

(2009) Keith Feigenson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

p57KIP2: "Kip"ing the Cell under Control

(2009) I. S. Pateras et al.   MOLECULAR CANCER RESEARCH

The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination

(2009) Ying Chen et al.   NATURE NEUROSCIENCE

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage

(2009) Jin Young Kim et al.   NATURE NEUROSCIENCE

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

(2009) Georgina S. Butler et al.   NATURE REVIEWS DRUG DISCOVERY

p57kip2 is dynamically regulated in experimental autoimmune encephalomyelitis and interferes with oligodendroglial maturation

(2009) D. Kremer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the Oligodendrogenic Program of Neural Progenitors: Cell Intrinsic and Extrinsic Regulators

(2009) Francisco J. Rivera et al.   STEM CELLS AND DEVELOPMENT

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Ascl1 is required for oligodendrocyte development in the spinal cord

(2008) M. Sugimori et al.   DEVELOPMENT

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Chromatin changes induced by lamin A/C deficiency and the histone deacetylase inhibitor trichostatin A

(2008) G GALIOVA et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Revisiting Notch in remyelination of multiple sclerosis lesions

(2008) Celia F. Brosnan et al.   JOURNAL OF CLINICAL INVESTIGATION

Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis

(2008) Jin Nakahara et al.   JOURNAL OF CLINICAL INVESTIGATION

The biology of CNS remyelination

(2008) Robin J. M. Franklin et al.   JOURNAL OF NEUROLOGY

Cdk5 Phosphorylation of WAVE2 Regulates Oligodendrocyte Precursor Cell Migration through Nonreceptor Tyrosine Kinase Fyn

(2008) Y. Miyamoto et al.   JOURNAL OF NEUROSCIENCE

A Novel Nuclear Signaling Pathway for Thromboxane A2 Receptors in Oligodendrocytes: Evidence for Signaling Compartmentalization during Differentiation

(2008) F. Mir et al.   MOLECULAR AND CELLULAR BIOLOGY

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

(2008) Akiko Nishiyama et al.   NATURE REVIEWS NEUROSCIENCE

Temporal–spatial expressions of p27kip1 and its phosphorylation on Serine-10 after acute spinal cord injury in adult rat: Implications for post-traumatic glial proliferation

(2008) Aiguo Shen et al.   NEUROCHEMISTRY INTERNATIONAL

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

(2008) Bastian G. Brinkmann et al.   NEURON

The many facets of Notch ligands

(2008) B D'Souza et al.   ONCOGENE

The Recently Identified P2Y-Like Receptor GPR17 Is a Sensor of Brain Damage and a New Target for Brain Repair

(2008) Davide Lecca et al.   PLoS One

The cyclin-dependent kinase inhibitor p57kip2 is a negative regulator of Schwann cell differentiation and in vitro myelination

(2008) A. Heinen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Export Signal Consensus Sequences Defined Using a Localization-Based Yeast Selection System

(2008) Shunichi Kosugi et al.   TRAFFIC