Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3

Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response

(2017) Rui Zhang et al.   JOURNAL OF VIROLOGY

miR-194-5p/BCLAF1 deregulation in AML tumorigenesis

(2017) C Dell'Aversana et al.   LEUKEMIA

Transcriptional Regulation of Antiviral Interferon-Stimulated Genes

(2017) Wenshi Wang et al.   TRENDS IN MICROBIOLOGY

Bclaf1 is an important NF-κB signaling transducer and C/EBPβ regulator in DNA damage-induced senescence

(2016) A-w Shao et al.   CELL DEATH AND DIFFERENTIATION

Negative regulation of type I IFN signaling by phosphorylation of STAT2 on T387

(2016) Yuxin Wang et al.   EMBO JOURNAL

Evasion of host antiviral innate immunity by HSV-1, an update

(2016) Chenhe Su et al.   Virology Journal

Viral Evasion Strategies in Type I IFN Signaling – A Summary of Recent Developments

(2016) Katharina S. Schulz et al.   Frontiers in Immunology

A simple and rapid approach to manipulate pseudorabies virus genome by CRISPR/Cas9 system

(2015) Aotian Xu et al.   BIOTECHNOLOGY LETTERS

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pseudorabies virus US3 leads to filamentous actin disassembly and contributes to viral genome delivery to the nucleus

(2015) Thary Jacob et al.   VETERINARY MICROBIOLOGY

Herpes Simplex Virus 1 Protein Kinase US3 Hyperphosphorylates p65/RelA and Dampens NF-κB Activation

(2014) Kezhen Wang et al.   JOURNAL OF VIROLOGY

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

(2014) Kienan I. Savage et al.   MOLECULAR CELL

BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells

(2014) Xuexia Zhou et al.   Nature Communications

An Inquiry into the Molecular Basis of HSV Latency and Reactivation

(2013) Bernard Roizman et al.   Annual Review of Microbiology

Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma

(2013) Laurence Lamy et al.   CANCER CELL

Update on Herpes Virus Infections of the Nervous System

(2013) Israel Steiner et al.   Current Neurology and Neuroscience Reports

Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production

(2013) Shuai Wang et al.   JOURNAL OF VIROLOGY

The ribosomal protein S26 regulates p53 activity in response to DNA damage

(2013) D Cui et al.   ONCOGENE

Suppression of apoptosis by pseudorabies virus Us3 protein kinase through the activation of PI3-K/Akt and NF-κB pathways

(2013) Ching-Dong Chang et al.   RESEARCH IN VETERINARY SCIENCE

Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylation

(2012) Torsten Ginter et al.   CELLULAR SIGNALLING

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Identification of STAT2 Serine 287 as a Novel Regulatory Phosphorylation Site in Type I Interferon-induced Cellular Responses

(2012) Håkan C. Steen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of alphaherpesvirus infections by the ICP0 family of proteins

(2012) C. Boutell et al.   JOURNAL OF GENERAL VIROLOGY

BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection

(2012) S. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of glycoprotein E of herpes simplex virus requires coordinated assembly of three tegument proteins on its cytoplasmic tail

(2012) J. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair

(2012) Y Y Lee et al.   Cell Death & Disease

Pseudorabies virus in wild swine: a global perspective

(2011) T. Müller et al.   ARCHIVES OF VIROLOGY

SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFN 

(2011) A. Begitt et al.   BLOOD

The Type III Histone Deacetylase Sirt1 Protein Suppresses p300-mediated Histone H3 Lysine 56 Acetylation at Bclaf1 Promoter to Inhibit T Cell Activation

(2011) Sinyi Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Alphaherpesvirus Serine/Threonine Kinase Us3 Disrupts Promyelocytic Leukemia Protein Nuclear Bodies

(2011) M. Jung et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Glycoprotein B and US3 Collaborate To Inhibit CD1d Antigen Presentation and NKT Cell Function

(2011) P. Rao et al.   JOURNAL OF VIROLOGY

US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis

(2011) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Keep it in the subfamily: the conserved alphaherpesvirus US3 protein kinase

(2010) M. J. Deruelle et al.   JOURNAL OF GENERAL VIROLOGY

Hyperphosphorylation of Histone Deacetylase 2 by Alphaherpesvirus US3 Kinases

(2010) M. S. Walters et al.   JOURNAL OF VIROLOGY

Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Mechanisms Employed by Herpes Simplex Virus 1 to Inhibit the Interferon Response

(2009) Patrick Paladino et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases

(2009) C. Van den Broeke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role for Bclaf1 in lung development and immune system function

(2008) J Peter McPherson et al.   CELL DEATH AND DIFFERENTIATION

Expression of Gamma Interferon-Dependent Genes Is Blocked Independently by Virion Host Shutoff RNase and by US3 Protein Kinase

(2008) L. Liang et al.   JOURNAL OF VIROLOGY

Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs

(2008) Joseph M Ziegelbauer et al.   NATURE GENETICS