miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

MicroRNA miR-181a/b-1 controls MAIT cell development

(2018) Samantha J Winter et al.   IMMUNOLOGY AND CELL BIOLOGY

Overexpression of Vα14Jα18 TCR promotes development of iNKT cells in the absence of miR-181a/b-1

(2016) Jonas Blume et al.   IMMUNOLOGY AND CELL BIOLOGY

mir-181a-1/b-1Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function

(2015) Steven A. Schaffert et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development

(2015) Inga Sandrock et al.   PLoS One

Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

(2014) J. Christoph Vahl et al.   IMMUNITY

Differential Requirement for IL-2 and IL-15 during Bifurcated Development of Thymic Regulatory T Cells

(2014) Daniel Marshall et al.   JOURNAL OF IMMUNOLOGY

The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens

(2014) Ross B Fulton et al.   NATURE IMMUNOLOGY

Continuous requirement for the TCR in regulatory T cell function

(2014) Andrew G Levine et al.   NATURE IMMUNOLOGY

Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC

(2014) Stephen P Persaud et al.   NATURE IMMUNOLOGY

Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

(2013) Xuguang Tai et al.   IMMUNITY

The MicroRNA miR-181 Is a Critical Cellular Metabolic Rheostat Essential for NKT Cell Ontogenesis and Lymphocyte Development and Homeostasis

(2013) Jorge Henao-Mejia et al.   IMMUNITY

Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis

(2013) Takashi Sekiya et al.   NATURE IMMUNOLOGY

Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

(2013) R. S. Paiva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells

(2013) N. Zietara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease

(2012) SuJin Hwang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamic MicroRNA Gene Transcription and Processing during T Cell Development

(2012) F. F. Kirigin et al.   JOURNAL OF IMMUNOLOGY

High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells

(2011) Lisa Föhse et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Helios Expression Is a Marker of T Cell Activation and Proliferation

(2011) Tatiana Akimova et al.   PLoS One

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions

(2011) Tomoyuki Yamaguchi et al.   SEMINARS IN IMMUNOLOGY

B7/CD28 in Central Tolerance: Costimulation Promotes Maturation of Regulatory T Cell Precursors and Prevents Their Clonal Deletion

(2011) Maria Hinterberger et al.   Frontiers in Immunology

CD28 Facilitates the Generation of Foxp3- Cytokine Responsive Regulatory T Cell Precursors

(2010) C. W. J. Lio et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD28 and c-Rel-Dependent Pathways Initiate Regulatory T Cell Development

(2010) K. B. Vang et al.   JOURNAL OF IMMUNOLOGY

How specificity for self-peptides shapes the development and function of regulatory T cells

(2010) Donald M. Simons et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance

(2010) Maria Hinterberger et al.   NATURE IMMUNOLOGY

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells

(2009) S. Duber et al.   BLOOD

CTLA‐4 is required by CD4+CD25+Treg to control CD4+T‐cell lymphopenia‐induced proliferation

(2009) Dorothy K. Sojka et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

(2009) Peter J R Ebert et al.   NATURE IMMUNOLOGY

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control

(2009) G. Wirnsberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE