Pro-apoptotic and pro-proliferation functions of the JNK pathway of Drosophila : roles in cell competition, tumorigenesis and regeneration

HMGB1 released by irradiated tumor cells promotes living tumor cell proliferation via paracrine effect

(2018) Sijia He et al.   Cell Death & Disease

Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis

(2018) Noelia Pinal et al.   Nature Communications

Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition

(2018) Lale Alpar et al.   DEVELOPMENTAL CELL

Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc

(2017) Amanda R. Brock et al.   GENETICS

The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition

(2017) Masatoshi Yamamoto et al.   NATURE

The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling

(2017) Sumbul Jawed Khan et al.   PLoS Genetics

Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc

(2017) Amanda R. Brock et al.   GENETICS

JNK at the crossroad of obesity, insulin resistance, and cell stress response

(2017) Giovanni Solinas et al.   Molecular Metabolism

JAK/STAT signalling mediates cell survival in response to tissue stress

(2016) Marco La Fortezza et al.   DEVELOPMENT

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs

(2016) Robin E Harris et al.   eLife

Apoptosis in Drosophila: which role for mitochondria?

(2015) Amandine Clavier et al.   APOPTOSIS

Mechanisms of apoptosis

(2015) M. A. Savitskaya et al.   BIOCHEMISTRY-MOSCOW

JNK signalling is necessary for a Wnt- and stem cell-dependent regeneration programme

(2015) B. Tejada-Romero et al.   DEVELOPMENT

Cell competition, apoptosis and tumour development

(2015) Ginés Morata et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Reactive Oxygen Species in Planarian Regeneration: An Upstream Necessity for Correct Patterning and Brain Formation

(2015) Nicky Pirotte et al.   Oxidative Medicine and Cellular Longevity

DuringDrosophiladisc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay

(2015) Tomonori Katsuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration

(2015) Paula Santabárbara-Ruiz et al.   PLoS Genetics

The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

(2014) Nicola J. Darling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dragging Ras Back in the Ring

(2014) Andrew G. Stephen et al.   CANCER CELL

JNK Controls the Onset of Mitosis in Planarian Stem Cells and Triggers Apoptotic Cell Death Required for Regeneration and Remodeling

(2014) María Almuedo-Castillo et al.   PLoS Genetics

Developmentally programmed cell death in Drosophila

(2013) Donna Denton et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

(2013) Nick R. Love et al.   NATURE CELL BIOLOGY

Cell competition may function either as tumour-suppressing or as tumour-stimulating factor in Drosophila

(2013) L Ballesteros-Arias et al.   ONCOGENE

Cell Death–Stimulated Cell Proliferation: A Tissue Regeneration Mechanism Usurped by Tumors During Radiotherapy

(2013) Mary A. Zimmerman et al.   SEMINARS IN RADIATION ONCOLOGY

Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed

(2013) Carole Gauron et al.   Scientific Reports

Drosophila at the intersection of infection, inflammation, and cancer

(2013) Erdem Bangi   Frontiers in Cellular and Infection Microbiology

The cell biology of regeneration

(2012) Ryan S. King et al.   JOURNAL OF CELL BIOLOGY

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila

(2011) E Shlevkov et al.   CELL DEATH AND DIFFERENTIATION

Mitogenic signaling from apoptotic cells in Drosophila

(2011) Ginés Morata et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

(2011) Qian Huang et al.   NATURE MEDICINE

Tumor suppression by cell competition through regulation of the Hippo pathway

(2011) C.-L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation

(2010) Binnaz Kucuk Staley et al.   CURRENT BIOLOGY

Cell death-induced regeneration in wing imaginal discs requires JNK signalling

(2010) C. Bergantinos et al.   DEVELOPMENT

Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors

(2010) Gongping Sun et al.   DEVELOPMENTAL BIOLOGY

Interaction between Ras V12 and scribbled clones induces tumour growth and invasion

(2010) Ming Wu et al.   NATURE

A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway

(2010) J. Menendez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling

(2009) Tatsushi Igaki   APOPTOSIS

Apoptosis in amphibian organs during metamorphosis

(2009) Atsuko Ishizuya-Oka et al.   APOPTOSIS

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc

(2009) A. Perez-Garijo et al.   DEVELOPMENT

Multiple Wnts are involved in Hydra organizer formation and regeneration

(2009) Tobias Lengfeld et al.   DEVELOPMENTAL BIOLOGY

Regenerative Growth in Drosophila Imaginal Discs Is Regulated by Wingless and Myc

(2009) Rachel K. Smith-Bolton et al.   DEVELOPMENTAL CELL

Apoptotic Cells Provide an Unexpected Source of Wnt3 Signaling to Drive Hydra Head Regeneration

(2009) Simona Chera et al.   DEVELOPMENTAL CELL

Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila

(2009) Tatsushi Igaki et al.   DEVELOPMENTAL CELL

The position and function of the Notch-mediated eye growth organizer: the roles of JAK/STAT and four-jointed

(2009) Francisco Jose Gutierrez-Aviño et al.   EMBO REPORTS

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Paracrine Unpaired Signaling through the JAK/STAT Pathway Controls Self-renewal and Lineage Differentiation of Drosophila Intestinal Stem Cells

(2009) G. Lin et al.   Journal of Molecular Cell Biology

Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration

(2008) Gufa Lin et al.   DEVELOPMENTAL BIOLOGY

Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer

(2008) Qingshan Chang et al.   JOURNAL OF HEPATOLOGY

 -Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis

(2007) K. A. Gurley et al.   SCIENCE

Smed- catenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration

(2007) C. P. Petersen et al.   SCIENCE