Orally Delivered Antisense Oligodeoxyribonucleotides of TNF-α via Polysaccharide-Based Nanocomposites Targeting Intestinal Inflammation

Modified Floating Electrode-Based Sensors for the Quantitative Monitoring of Drug Effects on Cytokine Levels Related with Inflammatory Bowel Diseases

(2018) Viet Anh Pham Ba et al.   ACS Applied Materials & Interfaces

Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer

(2018) Bo Xiao et al.   ACS Nano

Inflammatory bowel disease: new therapies from antisense oligonucleotides

(2018) Irene Marafini et al.   ANNALS OF MEDICINE

Oligonucleotide-Based Therapies for Inflammatory Bowel Disease

(2018) Gerolamo Bevivino et al.   BIODRUGS

Alternative foaming agents for topical treatment of ulcerative colitis

(2018) Martin Asama et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Ex Vivo Study of Telluride Nanowires in Minigut

(2018) Yijun Qi et al.   Journal of Biomedical Nanotechnology

Surface charge tunable nanoparticles for TNF-α siRNA oral delivery for treating ulcerative colitis

(2018) Shoaib Iqbal et al.   Nano Research

Synthesis and evaluation of 6-heteroarylamino-2,4,5-trimethylpyridin-3-ols as inhibitors of TNF-α-induced cell adhesion and inflammatory bowel disease

(2018) Sang Won Park et al.   MedChemComm

Systemic siRNA delivery to tumors by cell-penetrating α-helical polypeptide-based metastable nanoparticles

(2018) Yang Liu et al.   Nanoscale

A multi-functional macrophage and tumor targeting gene delivery system for the regulation of macrophage polarity and reversal of cancer immunoresistance

(2018) Xiao-Yan He et al.   Nanoscale

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

(2018) J. Scott Crowe et al.   Scientific Reports

Understanding and Preventing the Global Increase of Inflammatory Bowel Disease

(2017) Gilaad G. Kaplan et al.   GASTROENTEROLOGY

Intestinal organoids containing poly(lactic-co -glycolic acid) nanoparticles for the treatment of inflammatory bowel diseases

(2017) Zahra Davoudi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Encapsulation of methotrexate and cyclophosphamide in interpolymer complexes formed between poly acrylic acid and poly ethylene glycol on multi-walled carbon nanotubes as drug delivery systems

(2017) Mohammad Hossein Ahmadi Azqhandi et al.   Materials Science & Engineering C-Materials for Biological Applications

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

(2017) Bo Xiao et al.   MOLECULAR THERAPY

iRGD-functionalized PEGylated nanoparticles for enhanced colon tumor accumulation and targeted drug delivery

(2017) Lijun Ma et al.   Nanomedicine

In vivo gastrointestinal drug-release monitoring through second near-infrared window fluorescent bioimaging with orally delivered microcarriers

(2017) Rui Wang et al.   Nature Communications

Alpha-Tocopheryl Succinate-Conjugated G5 PAMAM Dendrimer Enables Effective Inhibition of Ulcerative Colitis

(2017) Yunan Wang et al.   Advanced Healthcare Materials

Newly Designed Silica-Containing Redox Nanoparticles for Oral Delivery of Novel TOP2 Catalytic Inhibitor for Treating Colon Cancer

(2017) Long Binh Vong et al.   Advanced Healthcare Materials

Progress in rigid polysaccharide-based nanocomposites with therapeutic functions

(2017) Qingye Liu et al.   Journal of Materials Chemistry B

Polyelectrolyte Complexes of Low Molecular Weight PEI and Citric Acid as Efficient and Nontoxic Vectors for in Vitro and in Vivo Gene Delivery

(2016) M. Dolores Giron-Gonzalez et al.   BIOCONJUGATE CHEMISTRY

RNAi-mediated silencing of TNF-α converting enzyme to down-regulate soluble TNF-α production for treatment of acute and chronic colitis

(2016) Yoonsung Song et al.   JOURNAL OF CONTROLLED RELEASE

Apigenin supplementation protects the development of dextran sulfate sodium-induced murine experimental colitis by inhibiting canonical and non-canonical inflammasome signaling pathways

(2016) Yazmín K. Márquez-Flores et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hypoglycemic activity of the Baker's yeast β-glucan in obese/type 2 diabetic mice and the underlying mechanism

(2016) Yan Cao et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Recent advances in liposome surface modification for oral drug delivery

(2016) Thanh Xuan Nguyen et al.   Nanomedicine

Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation

(2016) Bo Xiao et al.   Theranostics

An orally administrated nucleotide-delivery vehicle targeting colonic macrophages for the treatment of inflammatory bowel disease

(2015) Zhen Huang et al.   BIOMATERIALS

Curcumin–piperine mixtures in self-microemulsifying drug delivery system for ulcerative colitis therapy

(2015) Qiuping Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Specific accumulation of orally administered redox nanotherapeutics in the inflamed colon reducing inflammation with dose–response efficacy

(2015) Long Binh Vong et al.   JOURNAL OF CONTROLLED RELEASE

Oat β-glucan ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice

(2015) Bo Liu et al.   Food & Function

Transfection efficiency and internalization of the gene carrier prepared from a triple-helical β-glucan and polydeoxyadenylic acid in macrophage RAW264.7 cells

(2015) Qingye Liu et al.   Journal of Materials Chemistry B

Systematic review with meta-analysis: malignancies with anti-tumour necrosis factor-α therapy in inflammatory bowel disease

(2014) C. J. M. Williams et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

(2014) Bo Xiao et al.   GASTROENTEROLOGY

Macrophage-targeted delivery systems for nucleic acid therapy of inflammatory diseases

(2014) Amit Singh et al.   JOURNAL OF CONTROLLED RELEASE

A Paradigm Change: Efficient Transfection of Human Leukemia Cells by Stimuli-Responsive Multicompartment Micelles

(2013) Alexandra C. Rinkenauer et al.   ACS Nano

Methoxy poly(ethylene glycol)-block-polycaprolactone copolymer: formulation and optimization by experimental design; determination of diblock molar mass by multivariate regression analysis of 1H NMR spectra

(2013) Mohammad Reza Khanmohammadi et al.   Analytical Methods

Conjugation with Betaine: A Facile and Effective Approach to Significant Improvement of Gene Delivery Properties of PEI

(2013) Jun Sun et al.   BIOMACROMOLECULES

Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles

(2013) Sha Sha et al.   BIOMATERIALS

Biotin-Encoded and Fe3O4-Loaded Polymeric Nano Micelles: Preparation, Optimization and In Vitro Characterization

(2013) Mohammad Azqhandi et al.   Letters in Drug Design & Discovery

Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease

(2013) Ole Haagen Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A novel gene carrier prepared from triple helical β-glucan and polydeoxyadenylic acid

(2013) Qingye Liu et al.   Journal of Materials Chemistry B

Gene Silencing by Gold Nanoshell-Mediated Delivery and Laser-Triggered Release of Antisense Oligonucleotide and siRNA

(2012) Ryan Huschka et al.   ACS Nano

Variable chain conformations of renatured β-glucan in dimethylsulfoxide/water mixture

(2012) Qingye Liu et al.   BIOPOLYMERS

Interaction between polydeoxyadenylic acid and β-glucan from Lentinus edodes

(2012) Qingye Liu et al.   EUROPEAN POLYMER JOURNAL

An Orally Administered Redox Nanoparticle That Accumulates in the Colonic Mucosa and Reduces Colitis in Mice

(2012) Long Binh Vong et al.   GASTROENTEROLOGY

Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin

(2011) Xiao-Bing Xiong et al.   ACS Nano

In vivo treatment of tumors using host-guest conjugated nanoparticles functionalized with doxorubicin and therapeutic gene pTRAIL

(2011) Hui Fan et al.   BIOMATERIALS

Lipoic Acid Modified Low Molecular Weight Polyethylenimine Mediates Nontoxic and Highly Potentin VitroGene Transfection

(2011) Meng Zheng et al.   MOLECULAR PHARMACEUTICS

Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon

(2010) Hamed Laroui et al.   BIOMATERIALS

Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation☆

(2010) Hidetaka Akita et al.   JOURNAL OF CONTROLLED RELEASE

Targeting delivery oligonucleotide into macrophages by cationic polysaccharide from Bletilla striata successfully inhibited the expression of TNF-α

(2008) Lei Dong et al.   JOURNAL OF CONTROLLED RELEASE

Thermally Induced Conformation Transition of Triple-Helical Lentinan in NaCl Aqueous Solution

(2008) Xiaohua Wang et al.   JOURNAL OF PHYSICAL CHEMISTRY B