Immunoregulatory potential of mesenchymal stem cells following activation by macrophage-derived soluble factors

Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

(2018) Jacques Galipeau et al.   Cell Stem Cell

Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ

(2018) Dae Seong Kim et al.   EBioMedicine

IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity

(2017) Julia Braune et al.   JOURNAL OF IMMUNOLOGY

Inflammation and metabolism in tissue repair and regeneration

(2017) Sabine A. Eming et al.   SCIENCE

Immunoprivileged no more: measuring the immunogenicity of allogeneic adult mesenchymal stem cells

(2017) Alix K. Berglund et al.   Stem Cell Research & Therapy

Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis

(2017) Tzuhua Lin et al.   Stem Cell Research & Therapy

Safety Profile of Good Manufacturing Practice Manufactured Interferon γ-Primed Mesenchymal Stem/Stromal Cells for Clinical Trials

(2017) Adam J. Guess et al.   Stem Cells Translational Medicine

RANKL-induced M1 macrophages are involved in bone formation

(2017) Rong Huang et al.   Bone Research

Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?

(2017) Paul Lohan et al.   Frontiers in Immunology

To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

(2016) Jason A. Burdick et al.   Cell Stem Cell

Immune modulation with primed mesenchymal stem cells delivered via biodegradable scaffold to repair an Achilles tendon segmental defect

(2016) Erdem Aktas et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Reparative inflammation takes charge of tissue regeneration

(2016) Michael Karin et al.   NATURE

Resolution of Inflammation: What Controls Its Onset?

(2016) Michelle A. Sugimoto et al.   Frontiers in Immunology

Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism

(2016) Anoop Babu Vasandan et al.   Scientific Reports

Topographical cues regulate the crosstalk between MSCs and macrophages

(2015) Gema Vallés et al.   BIOMATERIALS

Identification of IL-1β and LPS as optimal activators of monolayer and alginate-encapsulated mesenchymal stromal cell immunomodulation using design of experiments and statistical methods

(2015) Andrea Gray et al.   BIOTECHNOLOGY PROGRESS

Primed Mesenchymal Stem Cells Alter and Improve Rat Medial Collateral Ligament Healing

(2015) Erin E. Saether et al.   Stem Cell Reviews and Reports

Primed Mesenchymal Stem Cells Alter and Improve Rat Medial Collateral Ligament Healing

(2015) Erin E. Saether et al.   Stem Cell Reviews and Reports

Materials as stem cell regulators

(2014) William L. Murphy et al.   NATURE MATERIALS

Mesenchymal stem cells: a new trend for cell therapy

(2013) Xin Wei et al.   ACTA PHARMACOLOGICA SINICA

Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation

(2013) Maria Ester Bernardo et al.   Cell Stem Cell

Macrophage phenotypes during tissue repair

(2013) Margaret L. Novak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

(2012) S. Willenborg et al.   BLOOD

Mesenchymal stem cells: a double-edged sword in regulating immune responses

(2012) W Li et al.   CELL DEATH AND DIFFERENTIATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Mesenchymal Stem/Stromal Cells Cultured as Spheroids are Self-activated to Produce Prostaglandin E2 that Directs Stimulated Macrophages into an Anti-inflammatory Phenotype

(2012) Joni H. YlÖstalo et al.   STEM CELLS

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation

(2011) Moïra François et al.   MOLECULAR THERAPY

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis

(2011) Marjolijn Duijvestein et al.   STEM CELLS

Role of CREB in modulation of TNFα and IL-10 expression in LPS-stimulated RAW264.7 macrophages

(2010) Dorit Avni et al.   MOLECULAR IMMUNOLOGY

Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice

(2009) Rita Mirza et al.   AMERICAN JOURNAL OF PATHOLOGY

The phenotype of murine wound macrophages

(2009) Jean M. Daley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

PRECONDITIONING MESENCHYMAL STEM CELLS WITH TRANSFORMING GROWTH FACTOR-ALPHA IMPROVES MESENCHYMAL STEM CELL-MEDIATED CARDIOPROTECTION

(2009) Jeremy L. Herrmann et al.   SHOCK

Mesenchymal Stem Cells Require a Sufficient, Ongoing Immune Response to Exert Their Immunosuppressive Function

(2009) P. Renner et al.   TRANSPLANTATION PROCEEDINGS

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE