Identification of IL-1β and LPS as optimal activators of monolayer and alginate-encapsulated mesenchymal stromal cell immunomodulation using design of experiments and statistical methods

Mesenchymal Stem Cells: A Friend or Foe in Immune-Mediated Diseases

(2015) Marina Gazdic et al.   Stem Cell Reviews and Reports

Mesenchymal Stem Cells: A Friend or Foe in Immune-Mediated Diseases

(2015) Marina Gazdic et al.   Stem Cell Reviews and Reports

Main Effect and Interactions of Brain Regions and Gender in the Calculation of Volumetric Asymmetry Indices in Healthy Human Brains: Ancova Analyses ofIn Vivo3T MRI Data

(2014) Ernesto Roldan-Valadez et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Fractional factorial design to investigate stromal cell regulation of macrophage plasticity

(2014) Jeffrey A. Barminko et al.   BIOTECHNOLOGY AND BIOENGINEERING

Unique characteristics of human mesenchymal stromal/progenitor cells pre-activated in 3-dimensional cultures under different conditions

(2014) Joni H. Ylostalo et al.   CYTOTHERAPY

Stimulation of mesenchymal stromal cells (MSCs) via TLR3 reveals a novel mechanism of autocrine priming

(2014) Claudia A. Dumitru et al.   FASEB JOURNAL

Analysis of the Effects of Five Factors Relevant to In Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput mRNA-Profiling

(2014) Rune B. Jakobsen et al.   PLoS One

Application of cell encapsulation for controlled delivery of biological therapeutics

(2013) G. Orive et al.   ADVANCED DRUG DELIVERY REVIEWS

Gender and age groups interactions in the quantification of bone marrow fat content in lumbar spine using 3T MR spectroscopy: A multivariate analysis of covariance (Mancova)

(2013) Ernesto Roldan-Valadez et al.   EUROPEAN JOURNAL OF RADIOLOGY

Dynamic compaction of human mesenchymal stem/precursor cells into spheres self-activates caspase-dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1)

(2013) Thomas J. Bartosh et al.   STEM CELLS

Pre-conditioned mesenchymal stem cells: a better way for cell-based therapy

(2013) Qing Li et al.   Stem Cell Research & Therapy

Mesenchymal Stem Cell-Based Therapy

(2012) Vaibhav Mundra et al.   MOLECULAR PHARMACEUTICS

Bone marrow mesenchymal stem cells can improve the motor function of a Huntington's disease rat model

(2012) Yufeng Jiang et al.   NEUROLOGICAL RESEARCH

Mesenchymal Stem Cell 1 (MSC1)-Based Therapy Attenuates Tumor Growth Whereas MSC2-Treatment Promotes Tumor Growth and Metastasis

(2012) Ruth S. Waterman et al.   PLoS One

Application of fractional factorial designs to study drug combinations

(2012) Jessica Jaynes et al.   STATISTICS IN MEDICINE

IL1β Induces Mesenchymal Stem Cells Migration and Leucocyte Chemotaxis Through NF-κB

(2012) Rubén Carrero et al.   Stem Cell Reviews and Reports

Human Mesenchymal Stem/Stromal Cells Cultured as Spheroids are Self-activated to Produce Prostaglandin E2 that Directs Stimulated Macrophages into an Anti-inflammatory Phenotype

(2012) Joni H. YlÖstalo et al.   STEM CELLS

How mesenchymal stem cells interact with tissue immune responses

(2012) Yufang Shi et al.   TRENDS IN IMMUNOLOGY

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

Encapsulated mesenchymal stromal cells for in vivo transplantation

(2011) Jeffrey Barminko et al.   BIOTECHNOLOGY AND BIOENGINEERING

Clinical trials for stem cell therapies

(2011) Alan Trounson et al.   BMC Medicine

Ligation of TLR2 and TLR4 on murine bone marrow-derived mesenchymal stem cells triggers differential effects on their immunosuppressive activity

(2011) Junxia Lei et al.   CELLULAR IMMUNOLOGY

Mesenchymal stromal cell ‘licensing’: a multistep process

(2011) M Krampera   LEUKEMIA

IL-6 and TGF-α Costimulate Mesenchymal Stem Cell Vascular Endothelial Growth Factor Production by ERK-, JNK-, and PI3K-Mediated Mechanisms

(2011) Jeremy L. Herrmann et al.   SHOCK

Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis

(2011) Marjolijn Duijvestein et al.   STEM CELLS

Pretreating mesenchymal stem cells with interleukin-1β and transforming growth factor-β synergistically increases vascular endothelial growth factor production and improves mesenchymal stem cell–mediated myocardial protection after acute ischemia

(2011) Yong Luo et al.   SURGERY

Microcapsules and microcarriers for in situ cell delivery☆

(2010) Rosa Ma Hernández et al.   ADVANCED DRUG DELIVERY REVIEWS

Cell encapsulation using biopolymer gels for regenerative medicine

(2010) Nicola C. Hunt et al.   BIOTECHNOLOGY LETTERS

Secretion profile of human bone marrow stromal cells: Donor variability and response to inflammatory stimuli

(2010) Victoria Zhukareva et al.   CYTOKINE

Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

(2010) Julian Maggini et al.   PLoS One

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

IL-6-Dependent PGE2 Secretion by Mesenchymal Stem Cells Inhibits Local Inflammation in Experimental Arthritis

(2010) Carine Bouffi et al.   PLoS One

Mesenchymal Stem Cell Homing: The Devil Is in the Details

(2009) Jeffrey M. Karp et al.   Cell Stem Cell

Mechanisms involved in the therapeutic properties of mesenchymal stem cells

(2009) Lindolfo da Silva Meirelles et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Chemical, physical and biological properties of alginates and their biomedical implications

(2009) Kurt I. Draget et al.   FOOD HYDROCOLLOIDS

Cytokine Modulation of TLR Expression and Activation in Mesenchymal Stromal Cells Leads to a Proinflammatory Phenotype

(2009) R. Romieu-Mourez et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem cells respond to TNF but do not produce TNF

(2009) Lieke C. J. van den Berk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cerebral transplantation of encapsulated mesenchymal stem cells improves cellular pathology after experimental traumatic brain injury

(2009) Anna M.B. Heile et al.   NEUROSCIENCE LETTERS

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Human mesenchymal stem cells stimulated by TNF-α, LPS, or hypoxia produce growth factors by an NFκB- but not JNK-dependent mechanism

(2008) Paul R. Crisostomo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Bioprocess optimization using design-of-experiments methodology

(2008) Carl-Fredrik Mandenius et al.   BIOTECHNOLOGY PROGRESS

Cell Delivery Mechanisms for Tissue Repair

(2008) David J. Mooney et al.   Cell Stem Cell

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

Evaluation and optimization of hepatocyte culture media factors by design of experiments (DoE) methodology

(2008) Jia Dong et al.   CYTOTECHNOLOGY

Effect of alginate on innate immune activation of macrophages

(2008) Dong Yang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses

(2008) H. Ohtaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-Like Receptors on Human Mesenchymal Stem Cells Drive Their Migration and Immunomodulating Responses

(2007) Suzanne L. Tomchuck et al.   STEM CELLS