Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology - a systematic review

(2013) Robert Klopfleisch   BMC Veterinary Research

Marine Compounds with Therapeutic Potential in Gram-Negative Sepsis

(2013) Tamara Solov'eva et al.   Marine Drugs

Gender differences in sepsis

(2013) Martin K Angele et al.   Virulence

TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis

(2012) Angela Castoldi et al.   PLoS One

Preclinical Sepsis Models

(2012) Tom van der Poll   Surgical Infections

Scavenger Receptor Class A Plays a Central Role in Mediating Mortality and the Development of the Pro-Inflammatory Phenotype in Polymicrobial Sepsis

(2012) Tammy R. Ozment et al.   PLoS Pathogens

Chitohexaose Activates Macrophages by Alternate Pathway through TLR4 and Blocks Endotoxemia

(2012) Santosh K. Panda et al.   PLoS Pathogens

Biological activities of chitosan and chitooligosaccharides

(2010) Wenshui Xia et al.   FOOD HYDROCOLLOIDS

Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress

(2010) Ying Qiao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis

(2010) X. Wittebole et al.   MEDIATORS OF INFLAMMATION

Peritoneal Negative Pressure Therapy Prevents Multiple Organ Injury in a Chronic Porcine Sepsis and Ischemia/Reperfusion Model

(2010) Brian D. Kubiak et al.   SHOCK

Combination of Imipenem and TAK-242, a Toll-Like Receptor 4 Signal Transduction Inhibitor, Improves Survival in a Murine Model of Polymicrobial Sepsis

(2010) Takukyu Sha et al.   SHOCK

Non-antibiotic strategies for sepsis

(2009) J. Cohen   CLINICAL MICROBIOLOGY AND INFECTION

Toll-Like Receptors 2 and 4 Contribute to Sepsis-Induced Depletion of Spleen Dendritic Cells

(2009) F. Pene et al.   INFECTION AND IMMUNITY

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4

(2009) T. Roger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other Diseases

(2008) Carlos G. Leon et al.   PHARMACEUTICAL RESEARCH