Chitohexaose Activates Macrophages by Alternate Pathway through TLR4 and Blocks Endotoxemia

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells

(2011) O. M. Pena et al.   JOURNAL OF IMMUNOLOGY

Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis

(2010) X. Wittebole et al.   MEDIATORS OF INFLAMMATION

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

SphK1 Regulates Proinflammatory Responses Associated with Endotoxin and Polymicrobial Sepsis

(2010) P. Puneet et al.   SCIENCE

Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase–dependent manner

(2009) Anje Cauwels et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recombinant Ov-ASP-1, a Th1-Biased Protein Adjuvant Derived from the Helminth Onchocerca volvulus, Can Directly Bind and Activate Antigen-Presenting Cells

(2009) Y. He et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated and Immunoregulatory Monocytes in Human Filarial Infections

(2009) Subash Babu et al.   JOURNAL OF INFECTIOUS DISEASES

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

The Novel Role of Platelet-Activating Factor in Protecting Mice against Lipopolysaccharide-Induced Endotoxic Shock

(2009) Young-Il Jeong et al.   PLoS One

Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4

(2009) T. Roger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

Development of a real-time polymerase chain reaction assay for the quantification of Leishmania species and the monitoring of systemic distribution of the pathogen

(2008) Nitin Tupperwar et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophagesin vivo

(2008) Olga Atochina et al.   IMMUNOLOGY

TLR4-induced IFN-γ production increases TLR2 sensitivity and drives Gram-negative sepsis in mice

(2008) Stephan Spiller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other Diseases

(2008) Carlos G. Leon et al.   PHARMACEUTICAL RESEARCH