Functional Proteins from Short Peptides: Dayhoff's Hypothesis Turns 50

Allosterically Regulated Phosphatase Activity from Peptide-PNA Conjugates Folded Through Hybridization

(2016) Takuya Machida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Short Self-Assembling Peptides Are Able to Bind to Copper and Activate Oxygen

(2016) Olga V. Makhlynets et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints

(2016) Robert G. Smock et al.   CELL

An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors

(2016) Paola Laurino et al.   PLOS BIOLOGY

Internal symmetry in protein structures: prevalence, functional relevance and evolution

(2015) Santhanam Balaji   CURRENT OPINION IN STRUCTURAL BIOLOGY

Exploring the repeat protein universe through computational protein design

(2015) TJ Brunette et al.   NATURE

RNA quaternary structure and global symmetry

(2015) Christopher P. Jones et al.   TRENDS IN BIOCHEMICAL SCIENCES

A vocabulary of ancient peptides at the origin of folded proteins

(2015) Vikram Alva et al.   eLife

The robustness and innovability of protein folds

(2014) Ágnes Tóth-Petróczy et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Short peptides self-assemble to produce catalytic amyloids

(2014) Caroline M. Rufo et al.   Nature Chemistry

Computational design of a self-assembling symmetrical β-propeller protein

(2014) Arnout R. D. Voet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An artificial PPR scaffold for programmable RNA recognition

(2014) Sandrine Coquille et al.   Nature Communications

On the Immortality of Television Sets: "Function" in the Human Genome According to the Evolution-Free Gospel of ENCODE

(2013) D. Graur et al.   Genome Biology and Evolution

New genes as drivers of phenotypic evolution

(2013) Sidi Chen et al.   NATURE REVIEWS GENETICS

β-Propeller Blades as Ancestral Peptides in Protein Evolution

(2013) Klaus O. Kopec et al.   PLoS One

Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein

(2013) L. M. Longo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designing proteins from simple motifs: opportunities in Top-Down Symmetric Deconstruction

(2012) Michael Blaber et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Modular Evolution and the Origins of Symmetry: Reconstruction of a Three-Fold Symmetric Globular Protein

(2011) Aron Broom et al.   STRUCTURE

Prototypes of elementary functional loops unravel evolutionary connections between protein functions

(2010) Alexander Goncearenco et al.   BIOINFORMATICS

The Proto-Ribosome: An Ancient Nano-machine for Peptide Bond Formation

(2010) Chen Davidovich et al.   ISRAEL JOURNAL OF CHEMISTRY

Experimental support for the evolution of symmetric protein architecture from a simple peptide motif

(2010) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The origin, evolution and structure of the protein world

(2009) Gustavo Caetano-Anollés et al.   BIOCHEMICAL JOURNAL

Synthesis and characterization of de novo designed peptides modelling the binding sites of [4Fe–4S] clusters in photosystem I

(2009) Mikhail L. Antonkine et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Big science, little science

(2009) Gregory A. Petsko   EMBO REPORTS

Self-Assembly and Evolution of Homomeric Protein Complexes

(2009) Gabriel Villar et al.   PHYSICAL REVIEW LETTERS

From the first protein structures to our current knowledge of protein folding: delights and scepticisms

(2008) Alan R. Fersht   NATURE REVIEWS MOLECULAR CELL BIOLOGY