Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers

Stereodivergent Direct Catalytic Asymmetric Mannich-Type Reactions of α-Isothiocyanato Ester with Ketimines

(2011) Gang Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biology-Oriented Synthesis

(2011) Stefan Wetzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides

(2011) Ji-Rong Huang et al.   CHEMICAL COMMUNICATIONS

Enantioselective synthesis of all-carbon quaternary stereogenic centers in acyclic systems

(2011) Jaya Prakash Das et al.   CHEMICAL COMMUNICATIONS

Highly Enantio- and Diastereoselective Synthesis of β-Methyl-γ-monofluoromethyl-Substituted Alcohols

(2011) Wenguo Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Enantioselective Amination of Morita-Baylis-Hillman Carbonates with Masked Ammonia: A Facile Method for the Synthesis of Unprotected α-Methylene-β-Amino Esters

(2011) Aijun Lin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxazaborolidinium Ion-Catalyzed Cyclopropanation of α-Substituted Acroleins: Enantioselective Synthesis of Cyclopropanes Bearing Two Chiral Quaternary Centers

(2011) Lizhu Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Catalytic Asymmetric Vinylogous Mannich-type (AVM) Reaction of Nonactivated α-Angelica Lactone

(2011) Lin Zhou et al.   ORGANIC LETTERS

Tertiary Amine-Catalyzed Chemoselective and Asymmetric [3 + 2] Annulation of Morita–Baylis–Hillman Carbonates of Isatins with Propargyl Sulfones

(2011) Jing Peng et al.   ORGANIC LETTERS

Highly Enantioselective Direct Vinylogous Michael Addition of γ-Butenolide to Enals

(2011) Adrien Quintard et al.   ORGANIC LETTERS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-catalyzed asymmetric conjugate addition reaction: formation of quaternary stereocenters

(2010) Christine Hawner et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Tandem Reaction to Construct Six-Membered Spirocyclic Oxindoles with Multiple Chiral Centres through a Formal [2+2+2] Annulation

(2010) Kun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Organocatalytic [3+2] Cyclisation Strategy for the Highly Enantioselective Synthesis of Spirooxindoles

(2010) Arnaud Voituriez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enhancements of screening collections to address areas of unmet medical need: an industry perspective

(2010) David H Drewry et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Dimeric Quinidine-Catalyzed Enantioselective Aminooxygenation of Oxindoles: An Organocatalytic Approach to 3-Hydroxyoxindole Derivatives

(2010) Tommy Bui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue

(2010) Xianxing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

Asymmetric Quadruple Aminocatalytic Domino Reactions to Fused Carbocycles Incorporating a Spirooxindole Motif

(2010) Kun Jiang et al.   ORGANIC LETTERS

Base-Accelerated Enantioselective Substitution of Morita−Baylis−Hillman Carbonates with Dialkyl Phosphine Oxides

(2010) Wangsheng Sun et al.   ORGANIC LETTERS

Organocatalytic and Electrophilic Approach to Oxindoles with C3-Quaternary Stereocenters

(2010) Jing Peng et al.   ORGANIC LETTERS

Direct Asymmetric Allylic Alkylation of Butenolides with Morita−Baylis−Hillman Carbonates

(2010) Hai-Lei Cui et al.   ORGANIC LETTERS

Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine

(2010) Wen-Bing Chen et al.   ORGANIC LETTERS

Construction of Two Vicinal Quaternary Carbons by Asymmetric Allylic Alkylation: Total Synthesis of Hyperolactone C and (−)-Biyouyanagin A

(2009) Chao Du et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Stereoablative Alkylation of 3-Halooxindoles: Facile Access to Oxindoles with C3 All-Carbon Quaternary Stereocenters

(2009) Sandy Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Natural Product Inspired Compound Collections

(2009) Kamal Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective Asymmetric N-Allylic Alkylation of Indoles with Morita-Baylis-Hillman Carbonates

(2009) Hai-Lei Cui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters

(2009) Giorgio Bencivenni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic asymmetric allylic alkylation of oxindoles with Morita–Baylis–Hillman carbonates

(2009) Kun Jiang et al.   CHEMICAL COMMUNICATIONS

Advances in Solution- and Solid-Phase Synthesis toward the Generation of Natural Product-like Libraries

(2009) Jyoti P. Nandy et al.   CHEMICAL REVIEWS

Dual Organocatalysis: Asymmetric Allylic-Allylic Alkylation of α,α-Dicyanoalkenes and Morita-Baylis-Hillman Carbonates

(2009) Hai-Lei Cui et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Iminium Ion Catalysis with a Novel Bifunctional Primary Amine Thiourea: Controlling Adjacent Quaternary and Tertiary Stereocenters

(2009) Patrizia Galzerano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Base-Free Phase-Transfer Reaction in Water-Rich Solvent

(2009) Rongjun He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Homodinuclear Mn(III)2−Schiff Base Complex for Catalytic Asymmetric 1,4-Additions of Oxindoles to Nitroalkenes

(2009) Yuko Kato et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Formation of Quaternary Stereocenters

(2009) Marco Bella et al.   SYNTHESIS-STUTTGART

Chiral phosphine-catalyzed regio- and enantioselective allylic amination of Morita–Baylis–Hillman acetates

(2009) Guang-Ning Ma et al.   TETRAHEDRON-ASYMMETRY

Enantioselective Synthesis of Spirocyclic Benzopyranones by Rhodium‐Catalyzed Intermolecular [4+2] Annulation

(2008) Daiki Hojo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Natural Product Inspired Tricyclic Benzopyrones by an Organocatalyzed Annulation Reaction

(2008) Herbert Waldmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A diastereo- and enantioselective synthesis of α-substituted anti-α,β-diaminophosphonic acid derivatives

(2008) Jeremy C. Wilt et al.   CHEMICAL COMMUNICATIONS

Discovery of Bifunctional Thiourea/Secondary-Amine Organocatalysts for the Highly Stereoselective Nitro-Mannich Reaction of α-Substituted Nitroacetates

(2008) Bo Han et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Phosphine-Catalyzed Enantioselective Construction of γ-Butenolides Through Substitution of Morita−Baylis−Hillman Acetates with 2-Trimethylsilyloxy Furan

(2008) Ying-Qing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Bench-Stable Homodinuclear Ni2−Schiff Base Complex for Catalytic Asymmetric Synthesis of α-Tetrasubstitutedanti-α,β-Diamino Acid Surrogates

(2008) Zhihua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolution of a Synthetic Strategy:  Total Synthesis of (±)-Welwitindolinone A Isonitrile

(2008) Sarah E. Reisman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY