Eicosapentaenoic Acid Improves Hepatic Metabolism and Reduces Inflammation Independent of Obesity in High-Fat-Fed Mice and in HepG2 Cells

Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases

(2018) Varman T. Samuel et al.   Cell Metabolism

Roux-en-Y gastric bypass surgery alters serum metabolites and fatty acids in patients with morbid obesity- A prospective exploratory pilot study

(2018) Nadeeja N. Wijayatunga et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Omega-3 Polyunsaturated Fatty Acids Time-Dependently Reduce Cell Viability and Oncogenic MicroRNA-21 Expression in Estrogen Receptor-Positive Breast Cancer Cells (MCF-7)

(2018) Lauren LeMay-Nedjelski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypertension, diabetes, atherosclerosis and NASH: Cause or consequence?

(2018) Amedeo Lonardo et al.   JOURNAL OF HEPATOLOGY

Omega-3 fatty acids in obesity and metabolic syndrome: a mechanistic update

(2018) Kembra Albracht-Schulte et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients

(2018) Dan Ye et al.   LIFE SCIENCES

Integrated analysis of hepatic mRNA and miRNA profiles identified molecular networks and potential biomarkers of NAFLD

(2018) Mingzhe Zhu et al.   Scientific Reports

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

(2018) Ryan M. Esquejo et al.   EBioMedicine

MiR-19a Affects Hepatocyte Autophagy via Regulating lncRNA NBR2 and AMPK/PPARα in D-GalN/Lipopolysaccharide-Stimulated Hepatocytes

(2017) Yan-Min Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Treatment options for alcoholic and non-alcoholic fatty liver disease: A review

(2017) Sukhpreet Singh et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

(2017) Angela Woods et al.   Cell Reports

Stress-activatedmiR-21/miR-21*in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption

(2016) Nicolas Calo et al.   GUT

EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

(2016)   JOURNAL OF HEPATOLOGY

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells

(2015) J. Zhang et al.   CANCER RESEARCH

Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells

(2015) Chongwen Xu et al.   CELL CYCLE

miR-21 regulates triglyceride and cholesterol metabolism in non-alcoholic fatty liver disease by targeting HMGCR

(2015) CHUANZHENG SUN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Circulating profiling reveals the effect of a polyunsaturated fatty acid-enriched diet on common microRNAs

(2015) Francisco J. Ortega et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

PUFA diets alter the microRNA expression profiles in an inflammation rat model

(2015) ZHENG ZHENG et al.   Molecular Medicine Reports

Performance of Serum microRNAs -122, -192 and -21 as Biomarkers in Patients with Non-Alcoholic Steatohepatitis

(2015) Philip P. Becker et al.   PLoS One

Does Fish Oil Have an Anti-Obesity Effect in Overweight/Obese Adults? A Meta-Analysis of Randomized Controlled Trials

(2015) Shichun Du et al.   PLoS One

Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver

(2013) Hiroya Yamada et al.   CLINICA CHIMICA ACTA

NAFLD—the next global epidemic

(2013) Katrina Ray   Nature Reviews Gastroenterology & Hepatology

Chronic Administration of Proanthocyanidins or Docosahexaenoic Acid Reversess the Increase of miR-33a and miR-122 in Dyslipidemic Obese Rats

(2013) Laura Baselga-Escudero et al.   PLoS One

miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression

(2012) Chandi Charan Mandal et al.   CARCINOGENESIS

(n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights

(2012) Nishan S. Kalupahana et al.   Advances in Nutrition

n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet

(2011) Fatima Kasbi Chadli et al.   BRITISH JOURNAL OF NUTRITION

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Immunity as a link between obesity and insulin resistance

(2011) Nishan S. Kalupahana et al.   MOLECULAR ASPECTS OF MEDICINE

PPARα Is Regulated by miR-21 and miR-27b in Human Liver

(2011) Katsuhiko Kida et al.   PHARMACEUTICAL RESEARCH

Eicosapentaenoic Acid Prevents and Reverses Insulin Resistance in High-Fat Diet-Induced Obese Mice via Modulation of Adipose Tissue Inflammation

(2010) Nishan S. Kalupahana et al.   JOURNAL OF NUTRITION

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty liver and lipotoxicity

(2009) Michael Trauner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Expression profiling of microRNAs by deep sequencing

(2009) C. J. Creighton et al.   BRIEFINGS IN BIOINFORMATICS

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Dietary Blueberry Attenuates Whole-Body Insulin Resistance in High Fat-Fed Mice by Reducing Adipocyte Death and Its Inflammatory Sequelae

(2009) Jason DeFuria et al.   JOURNAL OF NUTRITION

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL