Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

(2016) Linda S. Steelman et al.   Aging-US

CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling

(2015) Tao Wang et al.   Oncotarget

The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer

(2015) Tao Wang et al.   Oncotarget

Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21Cip1/WAF1pathways

(2013) Maria Zamkova et al.   CELL CYCLE

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

(2013) X. Deschenes-Simard et al.   GENES & DEVELOPMENT

Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN

(2013) X.-R. Wang et al.   NEURO-ONCOLOGY

Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition

(2013) L Guo et al.   ONCOGENE

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity

(2012) Appalaraju Jaggupilli et al.   Clinical & Developmental Immunology

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis

(2012) Upal K. Basu Roy et al.   INTERNATIONAL JOURNAL OF CANCER

ErbB receptor tyrosine kinase/NF- B signaling controls mammosphere formation in human breast cancer

(2012) K. Hinohara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miRNAs regulate stem cell self-renewal and differentiation

(2012) Zuoren Yu et al.   Frontiers in Genetics

The Role of Breast Cancer Stem Cells in Metastasis and Therapeutic Implications

(2011) Marco A. Velasco-Velázquez et al.   AMERICAN JOURNAL OF PATHOLOGY

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells

(2011) L. Lin et al.   CANCER RESEARCH

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation

(2011) Xavier C. Ding et al.   CELL CYCLE

Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype

(2011) S. Ricardo et al.   JOURNAL OF CLINICAL PATHOLOGY

Nuclear Factor  B-Dependent Neurite Remodeling Is Mediated by Notch Pathway

(2011) S. A. Bonini et al.   JOURNAL OF NEUROSCIENCE

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(2011) Yingchun Zhao et al.   MOLECULAR MEDICINE

Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b

(2010) Osong Kwon et al.   CARCINOGENESIS

Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

(2010) Salvatore Pece et al.   CELL

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Identification of CD44v6+/CD24− breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies

(2009) Eric L Snyder et al.   LABORATORY INVESTIGATION

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Breast cancer chemoresistance: Emerging importance of cancer stem cells

(2009) Suebwong Chuthapisith et al.   SURGICAL ONCOLOGY-OXFORD

Tissue-Specific Promoters Active in CD44+CD24-/low Breast Cancer Cells

(2008) G. J. Bauerschmitz et al.   CANCER RESEARCH

Cancer Stem Cells in Breast: Current Opinion and Future Challenges

(2008) Emmanuelle Charafe-Jauffret et al.   PATHOBIOLOGY

MicroRNA Expression and Identification of Putative miRNA Targets in Ovarian Cancer

(2008) Neetu Dahiya et al.   PLoS One

Cancer stem cell markers in common cancers – therapeutic implications

(2008) Thomas Klonisch et al.   TRENDS IN MOLECULAR MEDICINE