Probiotics: How Effective Are They in the Fight against Obesity?

The gut microbiota and its potential role in obesity

(2018) Shabana et al.   Future Microbiology

Human gut microbiome: hopes, threats and promises

(2018) Patrice D Cani   GUT

Major microbiota dysbiosis in severe obesity: fate after bariatric surgery

(2018) Judith Aron-Wisnewsky et al.   GUT

The development of probiotics therapy to obesity: a therapy that has gained considerable momentum

(2018) Yongbo Kang et al.   Hormones-International Journal of Endocrinology and Metabolism

Lactobacillus paracasei HII01, xylooligosaccharides, and synbiotics reduce gut disturbance in obese rats

(2018) Parameth Thiennimitr et al.   NUTRITION

Beneficial effects of a selected probiotic mixture administered to high fat-fed mice before and after the development of obesity

(2018) Marianna Roselli et al.   Journal of Functional Foods

Lactobacillus plantarum Strain Ln4 Attenuates Diet-Induced Obesity, Insulin Resistance, and Changes in Hepatic mRNA Levels Associated with Glucose and Lipid Metabolism

(2018) Eunjung Lee et al.   Nutrients

Dose-Dependent Effects of Multispecies Probiotic Supplementation on the Lipopolysaccharide (LPS) Level and Cardiometabolic Profile in Obese Postmenopausal Women: A 12-Week Randomized Clinical Trial

(2018) Monika Szulińska et al.   Nutrients

Probiotic Species in the Modulation of Gut Microbiota: An Overview

(2018) Md. Abul Kalam Azad et al.   Biomed Research International

Interplay of Gut Microbiota, Probiotics in Obesity: A Review

(2018) Ramesh Pothuraju et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Energy intake is associated with endotoxemia in apparently healthy men

(2018) Jacques Amar et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation

(2018) Kaisa Hiippala et al.   Nutrients

Single-species versus dual-species probiotic supplementation as an emerging therapeutic strategy for obesity

(2017) G. Karimi et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Lactobacillus rhamnosus NCDC17 ameliorates type-2 diabetes by improving gut function, oxidative stress and inflammation in high-fat-diet fed and streptozotocintreated rats

(2017) S. Singh et al.   Beneficial Microbes

The effects of the Lactobacillus casei strain on obesity in children: a pilot study

(2017) S. Nagata et al.   Beneficial Microbes

Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics

(2017) Mingqian He et al.   Cell and Bioscience

Gut Microbiota Modulation and Its Relationship with Obesity Using Prebiotic Fibers and Probiotics: A Review

(2017) Dinesh K. Dahiya et al.   Frontiers in Microbiology

Correlation between body mass index and faecal microbiota from children

(2016) A. Ignacio et al.   CLINICAL MICROBIOLOGY AND INFECTION

Beneficial metabolic effects of selected probiotics on diet-induced obesity and insulin resistance in mice are associated with improvement of dysbiotic gut microbiota

(2016) Jeanne Alard et al.   ENVIRONMENTAL MICROBIOLOGY

Antiobesity effect of Pediococcus pentosaceus LP28 on overweight subjects: a randomized, double-blind, placebo-controlled clinical trial

(2016) F Higashikawa et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Anti-obesity Effect of Yogurt Fermented by Lactobacillus plantarum Q180 in Diet-induced Obese Rats

(2016) Sun-Young Park et al.   Korean Journal for Food Science of Animal Resources

Beneficial effects of Bifidobacterium lactis on lipid profile and cytokines in patients with metabolic syndrome: A randomized trial. Effects of probiotics on metabolic syndrome

(2016) Luciana Jesus Bernini et al.   NUTRITION

The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial

(2016) Aline Corado Gomes et al.   Obesity

Long-term safety and efficacy of perinatal probiotic intervention: Evidence from a follow-up study of four randomized, double-blind, placebo-controlled trials

(2016) Krista Lundelin et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Anti-obesity effect of milk fermented by Lactobacillus plantarum NCDC 625 alone and in combination with herbs on high fat diet fed C57BL/6J mice

(2016) R. Pothuraju et al.   Beneficial Microbes

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

(2016) Claire L. Boulangé et al.   Genome Medicine

Intestinal removal of free fatty acids from hosts byLactobacillifor the treatment of obesity

(2016) Hea-Jong Chung et al.   FEBS Open Bio

Intestinal Microbiota Is Influenced by Gender and Body Mass Index

(2016) Carmen Haro et al.   PLoS One

Short Chain Fatty Acids Prevent High-fat-diet-induced Obesity in Mice by Regulating G Protein-coupled Receptors and Gut Microbiota

(2016) Yuanyuan Lu et al.   Scientific Reports

Comparison of the effect of daily consumption of probiotic compared with low-fat conventional yogurt on weight loss in healthy obese women following an energy-restricted diet: a randomized controlled trial1

(2015) Ameneh Madjd et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing

(2015) Chika Kasai et al.   BMC GASTROENTEROLOGY

Dietary modulation of the gut microbiota – a randomised controlled trial in obese postmenopausal women

(2015) Lena K. Brahe et al.   BRITISH JOURNAL OF NUTRITION

Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota

(2015) Paige V. Bauer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Novel opportunities for next-generation probiotics targeting metabolic syndrome

(2015) Patrice D Cani et al.   CURRENT OPINION IN BIOTECHNOLOGY

Probiotics for experimental obesity prevention: focus on strain dependence and viability of composition

(2015) Nazarii Kobyliak et al.   Endokrynologia Polska

Lactobacillus gasseriKS-13,Bifidobacterium bifidumG9-1, andBifidobacterium longumMM-2 Ingestion Induces a Less Inflammatory Cytokine Profile and a Potentially Beneficial Shift in Gut Microbiota in Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

(2015) Samuel J. Spaiser et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Anti-obesity Effect of Fermented Whey Beverage using Lactic Acid Bacteria in Diet-induced Obese Rats

(2015) Sung-Moon Hong et al.   Korean Journal for Food Science of Animal Resources

Pathophysiological role of host microbiota in the development of obesity

(2015) Nazarii Kobyliak et al.   Nutrition Journal

Probiotic yogurt improves body mass index and fasting insulin levels without affecting serum leptin and adiponectin levels in non-alcoholic fatty liver disease (NAFLD)

(2015) Safoora Nabavi et al.   Journal of Functional Foods

Influence of milk fermented with Lactobacillus rhamnosus NCDC 17 alone and in combination with herbal ingredients on diet induced adiposity and related gene expression in C57BL/6J mice

(2015) Ramesh Pothuraju et al.   Food & Function

The anti-obesity effects ofLactobacillus caseistrain Shirota versus Orlistat on high fat diet-induced obese rats

(2015) Golgis Karimi et al.   Food & Nutrition Research

Long Term Development of Gut Microbiota Composition in Atopic Children: Impact of Probiotics

(2015) N. B. M. M. Rutten et al.   PLoS One

Obesity Alters the Microbial Community Profile in Korean Adolescents

(2015) Hae-Jin Hu et al.   PLoS One

Co-Administration of Cholesterol-Lowering Probiotics and Anthraquinone from Cassia obtusifolia L. Ameliorate Non-Alcoholic Fatty Liver

(2015) Lu Mei et al.   PLoS One

Lactobacillus casei Shirota Supplementation Does Not Restore Gut Microbiota Composition and Gut Barrier in Metabolic Syndrome: A Randomized Pilot Study

(2015) Vanessa Stadlbauer et al.   PLoS One

Short-term periodic consumption of multiprobiotic from childhood improves insulin sensitivity, prevents development of non-alcoholic fatty liver disease and adiposity in adult rats with glutamate-induced obesity

(2014) Oleksandr Savcheniuk et al.   BMC Complementary and Alternative Medicine

Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice

(2014) Jingjing Wang et al.   ISME Journal

Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes

(2014) Alessandra Puddu et al.   MEDIATORS OF INFLAMMATION

Saccharomyces boulardii Administration Changes Gut Microbiota and Reduces Hepatic Steatosis, Low-Grade Inflammation, and Fat Mass in Obese and Type 2 Diabetic db/db Mice

(2014) A. Everard et al.   mBio

Probiotic Potential ofLactobacillusStrains with Antimicrobial Activity against Some Human Pathogenic Strains

(2014) Parisa Shokryazdan et al.   Biomed Research International

Contributions of Colonic Short-Chain Fatty Acid Receptors in Energy Homeostasis

(2014) Atsukazu Kuwahara   Frontiers in Endocrinology

The SCFA Receptor GPR43 and Energy Metabolism

(2014) Ikuo Kimura et al.   Frontiers in Endocrinology

Lactobacillus plantarum TN8 exhibits protective effects on lipid, hepatic and renal profiles in obese rat

(2013) Riadh Ben Salah et al.   ANAEROBE

Lactobacillus rhamnosus GG improves insulin sensitivity and reduces adiposity in high-fat diet-fed mice through enhancement of adiponectin production

(2013) Sun-Woo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of Lactobacillus salivarius Ls-33 on fecal microbiota in obese adolescents

(2013) Nadja Larsen et al.   CLINICAL NUTRITION

The Gut Microbiota Reduces Leptin Sensitivity and the Expression of the Obesity-Suppressing Neuropeptides Proglucagon (Gcg) and Brain-Derived Neurotrophic Factor (Bdnf) in the Central Nervous System

(2013) Erik Schéle et al.   ENDOCRINOLOGY

Anti-obesity effect of Lactobacillus gasseri SBT2055 accompanied by inhibition of pro-inflammatory gene expression in the visceral adipose tissue in diet-induced obese mice

(2013) Masaya Miyoshi et al.   EUROPEAN JOURNAL OF NUTRITION

Incretin hormones and the satiation signal

(2013) J J Holst   INTERNATIONAL JOURNAL OF OBESITY

Lactobacillus plantarumLG42 isolated from gajami sik-hae decreases body and fat pad weights in diet-induced obese mice

(2013) J.-E. Park et al.   JOURNAL OF APPLIED MICROBIOLOGY

Bifidobacterium adolescentis protects from the development of nonalcoholic steatohepatitis in a mouse model

(2013) Astrid Reichold et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients - a randomized double-blind placebo-controlled pilot study

(2013) Khaider K Sharafedtinov et al.   Nutrition Journal

ProbioticsL. plantarumandL. curvatusin Combination Alter Hepatic Lipid Metabolism and Suppress Diet-Induced Obesity

(2013) Sae-Rom Yoo et al.   Obesity

Anti-Obesity Effect of Lactobacillus gasseri BNR17 in High-Sucrose Diet-Induced Obese Mice

(2013) Ji-Hee Kang et al.   PLoS One

Gut Microbiota Composition in Male Rat Models under Different Nutritional Status and Physical Activity and Its Association with Serum Leptin and Ghrelin Levels

(2013) María Isabel Queipo-Ortuño et al.   PLoS One

Microbial Reprogramming Inhibits Western Diet-Associated Obesity

(2013) Theofilos Poutahidis et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of intestinal homeostasis and immunity with probiotic lactobacilli

(2013) Peter van Baarlen et al.   TRENDS IN IMMUNOLOGY

Effect of Lactobacillus acidophilus NCDC 13 supplementation on the progression of obesity in diet-induced obese mice

(2012) Tulika Arora et al.   BRITISH JOURNAL OF NUTRITION

Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity

(2012) Eileen F Murphy et al.   GUT

Probiotics to Adolescents With Obesity

(2012) Rikke Juul Gøbel et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The Obesity and Fatty Liver Are Reduced by Plant-Derived Pediococcus pentosaceus LP28 in High Fat Diet-Induced Obese Mice

(2012) Xingrong Zhao et al.   PLoS One

Bacteroides uniformis CECT 7771 Ameliorates Metabolic and Immunological Dysfunction in Mice with High-Fat-Diet Induced Obesity

(2012) Paola Gauffin Cano et al.   PLoS One

Evaluation of clinical safety and tolerance of a Lactobacillus reuteri NCIMB 30242 supplement capsule: A randomized control trial

(2012) Mitchell L. Jones et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Modulation of the murine microbiome with a concomitant anti-obesity effect by Lactobacillus rhamnosus GG and Lactobacillus sakei NR28

(2012) Y. Ji et al.   Beneficial Microbes

Differential Targeting of the E-Cadherin/β-Catenin Complex by Gram-Positive Probiotic Lactobacilli Improves Epithelial Barrier Function

(2011) Stephanie Hummel et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bifidobacterium adolescentis supplementation ameliorates visceral fat accumulation and insulin sensitivity in an experimental model of the metabolic syndrome

(2011) Jinjin Chen et al.   BRITISH JOURNAL OF NUTRITION

Probiotics and immune health

(2011) Fang Yan et al.   CURRENT OPINION IN GASTROENTEROLOGY

Effect of functional yogurt NY-YP901 in improving the trait of metabolic syndrome

(2011) B J Chang et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Lactobacillus plantarum strain No. 14 reduces adipocyte size in mice fed high-fat diet

(2011) Naoki Takemura et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: Bacteriocins and conjugated linoleic acid

(2011) Eileen F. O'Shea et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii

(2011) M Million et al.   INTERNATIONAL JOURNAL OF OBESITY

Gut microbiome, obesity, and metabolic dysfunction

(2011) Herbert Tilg et al.   JOURNAL OF CLINICAL INVESTIGATION

Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes

(2011) Thomas Obsen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats

(2011) Hyang An et al.   Lipids in Health and Disease

Immunomodulatory mechanisms of lactobacilli

(2011) Jerry M Wells   Microbial Cell Factories

Probiotic bacteria and intestinal epithelial barrier function

(2010) Christina L. Ohland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Novel ProbioticBifidobacterium bifidumCECT 7366 Strain Active against the Pathogenic BacteriumHelicobacter pylori

(2010) E. Chenoll et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The bile acid sensor FXR regulates insulin transcription and secretion

(2010) Barbara Renga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation

(2010) Rachel C Anderson et al.   BMC MICROBIOLOGY

Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women

(2010) A. Santacruz et al.   BRITISH JOURNAL OF NUTRITION

Absence of intestinal microbiota does not protect mice from diet-induced obesity

(2010) Christine K. Fleissner et al.   BRITISH JOURNAL OF NUTRITION

Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial

(2010) Y Kadooka et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

The effect of bacteriocin-producing Lactobacillus plantarum strains on the intracellular pH of sessile and planktonic Listeria monocytogenes single cells

(2010) Dennis S. Nielsen et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The impact of perinatal probiotic intervention on the development of overweight and obesity: follow-up study from birth to 10 years

(2010) R Luoto et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats

(2010) Ji-Hee Kang et al.   JOURNAL OF MICROBIOLOGY

Effects of fourBifidobacteriaon obesity in high-fat diet induced rats

(2010) Ya-Ni Yin   WORLD JOURNAL OF GASTROENTEROLOGY

Quantitative differences in intestinal Faecalibacterium prausnitzii in obese Indian children

(2009) Ramadass Balamurugan et al.   BRITISH JOURNAL OF NUTRITION

Antiobesity mechanisms of action of conjugated linoleic acid

(2009) Arion Kennedy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

Milk fermented by Lactobacillus gasseri SBT2055 influences adipocyte size via inhibition of dietary fat absorption in Zucker rats

(2008) Essam M. Hamad et al.   BRITISH JOURNAL OF NUTRITION

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

(2008) Harry J. Flint et al.   NATURE REVIEWS MICROBIOLOGY

High-fat diet-induced obesity is attenuated by probiotic strain Lactobacillus paracasei ST11 (NCC2461) in rats

(2008) Mamoru Tanida et al.   Obesity Research & Clinical Practice

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probiotics, prebiotics and competitive exclusion for prophylaxis against bacterial disease

(2008) T. R. Callaway et al.   ANIMAL HEALTH RESEARCH REVIEWS