Incretin hormones and the satiation signal

Liraglutide: short-lived effect on gastric emptying-long lasting effects on body weight

(2012) J. Jelsing et al.   DIABETES OBESITY & METABOLISM

The Glucagon-Like Peptide 1 (GLP-1) Analogue, Exendin-4, Decreases the Rewarding Value of Food: A New Role for Mesolimbic GLP-1 Receptors

(2012) S. L. Dickson et al.   JOURNAL OF NEUROSCIENCE

The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1

(2011) Matthew R. Hayes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Short-term effects of liraglutide on visceral fat adiposity, appetite, and food preference: a pilot study of obese Japanese patients with type 2 diabetes

(2011) Kana Inoue et al.   Cardiovascular Diabetology

Gastric Bypass Surgery Enhances Glucagon-Like Peptide 1-Stimulated Postprandial Insulin Secretion in Humans

(2011) M. Salehi et al.   DIABETES

Gastric bypass surgery, but not caloric restriction, decreases dipeptidyl peptidase-4 activity in obese patients with type 2 diabetes

(2011) M. L. Alam et al.   DIABETES OBESITY & METABOLISM

Peripheral and Central GLP-1 Receptor Populations Mediate the Anorectic Effects of Peripherally Administered GLP-1 Receptor Agonists, Liraglutide and Exendin-4

(2011) Scott E. Kanoski et al.   ENDOCRINOLOGY

GLP-1 Neurons in the Nucleus of the Solitary Tract Project Directly to the Ventral Tegmental Area and Nucleus Accumbens to Control for Food Intake

(2011) Amber L. Alhadeff et al.   ENDOCRINOLOGY

Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide

(2011) A Astrup et al.   INTERNATIONAL JOURNAL OF OBESITY

Transgenic Rescue of Adipocyte Glucose-dependent Insulinotropic Polypeptide Receptor Expression Restores High Fat Diet-induced Body Weight Gain

(2011) Randi Ugleholdt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides

(2011) Y. Falkén et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hyperphagia and Increased Fat Accumulation in Two Models of Chronic CNS Glucagon-Like Peptide-1 Loss of Function

(2011) J. G. Barrera et al.   JOURNAL OF NEUROSCIENCE

Glucagon-Like Peptide 1 Receptors in Nucleus Accumbens Affect Food Intake

(2011) A. M. Dossat et al.   JOURNAL OF NEUROSCIENCE

Exenatide as a Weight-Loss Therapy in Extreme Pediatric Obesity: A Randomized, Controlled Pilot Study

(2011) Aaron S. Kelly et al.   Obesity

Nutrient detection by incretin hormone secreting cells

(2011) Eleftheria Diakogiannaki et al.   PHYSIOLOGY & BEHAVIOR

A Novel Human-Based Receptor Antagonist of Sustained Action Reveals Body Weight Control by Endogenous GLP-1

(2010) James T. Patterson et al.   ACS Chemical Biology

Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist

(2010) Elena-Dana Baraboi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effects of glucagon-like peptide 1 and oxyntomodulin on neuronal activity of ghrelin-sensitive neurons in the hypothalamic arcuate nucleus

(2010) Thomas Riediger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Remission of Type 2 Diabetes After Gastric Bypass and Banding

(2010) Dimitrios J. Pournaras et al.   ANNALS OF SURGERY

Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius

(2010) Kazunari Hisadome et al.   DIABETES

Bariatric surgery in patients with Type 2 diabetes: benefits, risks, indications and perspectives

(2010) A.-J. Scheen et al.   DIABETES & METABOLISM

Effects of Exenatide and Lifestyle Modification on Body Weight and Glucose Tolerance in Obese Subjects With and Without Pre-Diabetes

(2010) J. Rosenstock et al.   DIABETES CARE

Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes

(2010) A. Garber et al.   DIABETES OBESITY & METABOLISM

Effects of pre-meal versus post-meal administration of miglitol on plasma glucagon-like peptide-1 and glucosedependent insulinotropic polypeptide levels in healthy men

(2010) Kazutaka Aoki et al.   ENDOCRINE JOURNAL

The role of gut hormones and the hypothalamus in appetite regulation

(2010) Keisuke Suzuki et al.   ENDOCRINE JOURNAL

Effects of Fat Supplementation on Postprandial GIP, GLP-1, Ghrelin and IGFBP-1 Levels: A Pilot Study on Adolescents with Type 1 Diabetes

(2010) M. Lodefalk et al.   Hormone Research in Paediatrics

Effect of Administration Time of Exenatide on Satiety Responses, Blood Glucose, and Adverse Events in Healthy Volunteers

(2010) Nicole R. Pinelli et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Hepatic-Portal Vein Infusions of Glucagon-Like Peptide-1 Reduce Meal Size and Increase c-Fos Expression in the Nucleus Tractus Solitarii, Area Postrema and Central Nucleus of the Amygdala in Rats

(2010) I. Baumgartner et al.   JOURNAL OF NEUROENDOCRINOLOGY

Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

(2010) T. Edholm et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: Role of peripherally secreted and centrally produced peptides

(2010) Niels Vrang et al.   PROGRESS IN NEUROBIOLOGY

Unraveling the Science of Incretin Biology

(2009) Michael A. Nauck   AMERICAN JOURNAL OF MEDICINE

On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

(2009) Meena Asmar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Postprandial Diabetic Glucose Tolerance Is Normalized by Gastric Bypass Feeding as Opposed to Gastric Feeding and Is Associated With Exaggerated GLP-1 Secretion: A case report

(2009) C. Dirksen et al.   DIABETES CARE

The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: an overview of the LEAD 1-5 studies

(2009) L. Blonde et al.   DIABETES OBESITY & METABOLISM

Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue

(2009) J. Jendle et al.   DIABETES OBESITY & METABOLISM

Exenatide efficacy and safety: a systematic review

(2009) S. L. Norris et al.   DIABETIC MEDICINE

Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial

(2009) D. Russell-Jones et al.   DIABETOLOGIA

Resolution of type 2 diabetes following gastric bypass surgery: involvement of gut-derived glucagon and glucagonotropic signalling?

(2009) F. K. Knop   DIABETOLOGIA

Minireview: Finding the Sweet Spot: PeripheralVersusCentral Glucagon-Like Peptide 1 Action in Feeding and Glucose Homeostasis

(2009) Diana L. Williams   ENDOCRINOLOGY

Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials

(2009) Matteo Monami et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake

(2009) H J Grill et al.   INTERNATIONAL JOURNAL OF OBESITY

Secretion and Dipeptidyl Peptidase-4-Mediated Metabolism of Incretin Hormones after a Mixed Meal or Glucose Ingestion in Obese Compared to Lean, Nondiabetic Men

(2009) Richard D. Carr et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Comparable effects of moderate intensity exercise on changes in anorectic gut hormone levels and energy intake to high intensity exercise

(2009) Shin-ya Ueda et al.   JOURNAL OF ENDOCRINOLOGY

Vagally mediated effects of glucagon-like peptide 1:in vitroandin vivogastric actions

(2009) Gregory M. Holmes et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

(2009) Arne Astrup et al.   LANCET

Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)

(2009) John B Buse et al.   LANCET

Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat

(2009) v. bucinskaite et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Adding Liraglutide to Oral Antidiabetic Drug Monotherapy: Efficacy and Weight Benefits

(2009) Michael Nauck et al.   POSTGRADUATE MEDICINE

Impact of Incretin Therapy on Islet Dysfunction: An Underlying Defect in the Pathophysiology of Type 2 Diabetes

(2009) Janet B. McGill   POSTGRADUATE MEDICINE

Arcuate Glucagon-Like Peptide 1 Receptors Regulate Glucose Homeostasis but Not Food Intake

(2008) D. A. Sandoval et al.   DIABETES

Efficacy and Safety Comparison of Liraglutide, Glimepiride, and Placebo, All in Combination With Metformin, in Type 2 Diabetes: The LEAD (Liraglutide Effect and Action in Diabetes)-2 study

(2008) M. Nauck et al.   DIABETES CARE

Insulin Regulates Glucagon-Like Peptide-1 Secretion from the Enteroendocrine L Cell

(2008) Gareth E. Lim et al.   ENDOCRINOLOGY

Intrameal Hepatic Portal and Intraperitoneal Infusions of Glucagon-Like Peptide-1 Reduce Spontaneous Meal Size in the Rat via Different Mechanisms

(2008) Elisabeth B. Rüttimann et al.   ENDOCRINOLOGY

Evidence that Intestinal Glucagon-Like Peptide-1 Plays a Physiological Role in Satiety

(2008) Diana L. Williams et al.   ENDOCRINOLOGY

GLP-1 and Appetite Responses to a Meal in Lean and Overweight Adolescents Following Exercise

(2008) Jean-Pierre Chanoine et al.   Obesity

Mechanisms of action of CCK to activate central vagal afferent terminals

(2008) Richard C. Rogers et al.   PEPTIDES

Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes

(2008) Helle Linnebjerg et al.   REGULATORY PEPTIDES

Glucagon-like peptide-1, glucose homeostasis and diabetes

(2008) Jens J. Holst et al.   TRENDS IN MOLECULAR MEDICINE

The entero-insular axis: implications for human metabolism

(2007) Lakshminarayan R. Ranganath   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

(2007) Carolyn et al.   Frontiers in Bioscience-Landmark