Silver, Gold, and Iron Oxide Nanoparticles Alter miRNA Expression but Do Not Affect DNA Methylation in HepG2 Cells

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

(2019) Lu Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Silver nanoparticles impair zebrafish skeletal and cardiac myofibrillogenesis and sarcomere formation

(2018) Qin-Han Xu et al.   AQUATIC TOXICOLOGY

MicroRNA-499a decelerates glioma cell proliferation while accelerating apoptosis through the suppression of Notch1 and the MAPK signaling pathway

(2018) Bang-Qing Wang et al.   BRAIN RESEARCH BULLETIN

Gold nanoparticles induce serum amyloid A 1–Toll-like receptor 2 mediated NF- k B signaling in lung cells in vitro

(2018) Cheng Teng Ng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

miR-15b-5p facilitates the tumorigenicity by targeting RECK and predicts tumour recurrence in prostate cancer

(2018) Ran Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

(2018) Deniz Öner et al.   Particle and Fibre Toxicology

Long non‑coding RNA TUG1 promotes osteosarcoma cell proliferation and invasion through inhibition of microRNA‑212‑3p expression

(2018) Heng Li et al.   Experimental and Therapeutic Medicine

RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells

(2018) Anda R. Gliga et al.   Scientific Reports

Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity

(2018) Agnieszka Grzelak et al.   Redox Biology

The miR-15b-5p/PDK4 axis regulates osteosarcoma proliferation through modulation of the Warburg effect

(2018) Yiping Weng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-122-5p Inhibits the Proliferation, Invasion and Growth of Bile Duct Carcinoma Cells by Targeting ALDOA

(2018) Zhuo Xu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Short- and long-term gene expression profiles induced by inhaled TiO2 nanostructured aerosol in rat lung

(2018) Laëtitia Chézeau et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Impact of silver, gold, and iron oxide nanoparticles on cellular response to tumor necrosis factor

(2018) Kamil Brzóska et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Gold nanoparticles-induced cytotoxicity in triple negative breast cancer involves different epigenetic alterations depending upon the surface charge

(2018) Sunil Kumar Surapaneni et al.   Scientific Reports

Epigenetic modulations in nanoparticle-mediated toxicity

(2017) Belinda Shu Ee Wong et al.   FOOD AND CHEMICAL TOXICOLOGY

DNA methylation alterations induced by transient exposure of MCF-7 cells to maghemite nanoparticles

(2017) Raphael S Bonadio et al.   Nanomedicine

Identification of Four Oxidative Stress-Responsive MicroRNAs, miR-34a-5p, miR-1915-3p, miR-638, and miR-150-3p, in Hepatocellular Carcinoma

(2017) Yong Wan et al.   Oxidative Medicine and Cellular Longevity

Titanium dioxide aggregating nanoparticles induce autophagy and under-expression of microRNA 21 and 30a in A549 cell line: A comparative study with cobalt(II, III) oxide nanoparticles

(2017) Rossella Alinovi et al.   TOXICOLOGY IN VITRO

Silver nanoparticle-induced phosphorylation of histone H3 at serine 10 is due to dynamic changes in actin filaments and the activation of Aurora kinases

(2017) Xiaoxu Zhao et al.   TOXICOLOGY LETTERS

Changes in DNA Methylation in Mouse Lungs after a Single Intra-Tracheal Administration of Nanomaterials

(2017) Ali M. Tabish et al.   PLoS One

Polyvinyl pyrrolidone-coated silver nanoparticles in a human lung cancer cells: time- and dose-dependent influence over p53 and caspase-3 protein expression and epigenetic effects

(2016) Jordi Blanco et al.   ARCHIVES OF TOXICOLOGY

Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation

(2016) Deepti Dileep Deobagkar et al.   International Journal of Nanomedicine

The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome

(2016) Marta I. Sierra et al.   International Journal of Nanomedicine

Coexposure to silver nanoparticles and ultraviolet A synergistically enhances the phosphorylation of histone H2AX

(2016) Xiaoxu Zhao et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Prolonged Effects of Silver Nanoparticles on p53/p21 Pathway-Mediated Proliferation, DNA Damage Response, and Methylation Parameters in HT22 Hippocampal Neuronal Cells

(2016) Jennifer Mytych et al.   MOLECULAR NEUROBIOLOGY

Integrative analysis of genes and miRNA alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles

(2016) Jung-Hwa Oh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

DNA Hypermethylation of CREB3L1 and Bcl-2 Associated with the Mitochondrial-Mediated Apoptosis via PI3K/Akt Pathway in Human BEAS-2B Cells Exposure to Silica Nanoparticles

(2016) Yang Zou et al.   PLoS One

Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation

(2016) Junyi Li et al.   Scientific Reports

MicroRNA sequencing and molecular mechanisms analysis of the effects of gold nanoparticles on human dermal fibroblasts

(2015) Yan Huang et al.   BIOMATERIALS

Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status

(2015) Yi Qian et al.   BIOMATERIALS

Evaluating the Toxicity of Silver Nanoparticles by Detecting Phosphorylation of Histone H3 in Combination with Flow Cytometry Side-Scattered Light

(2015) Xiaoxu Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Adaptation of HepG2 cells to silver nanoparticles-induced stress is based on the pro-proliferative and anti-apoptotic changes in gene expression

(2015) Kamil Brzóska et al.   MUTAGENESIS

Short-term exposure to engineered nanomaterials affects cellular epigenome

(2015) Xiaoyan Lu et al.   Nanotoxicology

In vivoepigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles

(2015) Xiaoyan Lu et al.   Nanotoxicology

Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond

(2015) Achim Breiling et al.   Epigenetics & Chromatin

miR-656 inhibits glioma tumorigenesis through repression of BMPR1A

(2014) M. Guo et al.   CARCINOGENESIS

Toxicity of Silver Nanoparticles to Human Dermal Fibroblasts on MicroRNA Level

(2014) Yan Huang et al.   Journal of Biomedical Nanotechnology

Silver nanoparticles induced changes in the expression of NF-κB related genes are cell type specific and related to the basal activity of NF-κB

(2014) T.M. Stępkowski et al.   TOXICOLOGY IN VITRO

Integrated mRNA and micro RNA profiling reveals epigenetic mechanism of differential sensitivity of Jurkat T cells to AgNPs and Ag ions

(2014) Hyun-Jeong Eom et al.   TOXICOLOGY LETTERS

miR-1285-3p acts as a potential tumor suppressor miRNA via downregulating JUN expression in hepatocellular carcinoma

(2014) Jibing Liu et al.   TUMOR BIOLOGY

Transplacental clastogenic and epigenetic effects of gold nanoparticles in mice

(2013) Roumen Balansky et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Liver-specific microRNAs as biomarkers of nanomaterial-induced liver damage

(2013) Takashi Nagano et al.   NANOTECHNOLOGY

Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF- 

(2013) B. Guennewig et al.   RNA

Oxidative DNA damage corresponds to the long term survival of human cells treated with silver nanoparticles

(2013) Marcin Kruszewski et al.   TOXICOLOGY LETTERS

MicroRNA miR-491-5p Targeting both TP53 and Bcl-XL Induces Cell Apoptosis in SW1990 Pancreatic Cancer Cells through Mitochondria Mediated Pathway

(2012) Rong Guo et al.   MOLECULES

Epigenetics and the environment: emerging patterns and implications

(2012) Robert Feil et al.   NATURE REVIEWS GENETICS

Methylation of PARP-1 promoter involved in the regulation of nano-SiO2-induced decrease of PARP-1 mRNA expression

(2012) Chunmei Gong et al.   TOXICOLOGY LETTERS

Assessment of nanomaterial cytotoxicity with SOLiD sequencing-based microRNA expression profiling

(2011) Shuchun Li et al.   BIOMATERIALS

The induction of epigenetic regulation of PROS1 gene in lung fibroblasts by gold nanoparticles and implications for potential lung injury

(2011) Cheng-Teng Ng et al.   BIOMATERIALS

Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study

(2011) Sabina Halappanavar et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells

(2011) Anna Lankoff et al.   TOXICOLOGY LETTERS

Role of epigenetic events in chemical carcinogenesis—a justification for incorporating epigenetic evaluations in cancer risk assessment

(2011) Igor Koturbash et al.   TOXICOLOGY MECHANISMS AND METHODS

SiO2 nanoparticles induce global genomic hypomethylation in HaCaT cells

(2010) Chunmei Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL