Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-03-21
DOI
10.1038/s41467-019-09179-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
- (2018) Milica Momcilovic et al. CANCER CELL
- Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells
- (2018) Victoria J. Gennaro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell-Cycle Therapeutics Come of Age
- (2017) Matthew Ingham et al. JOURNAL OF CLINICAL ONCOLOGY
- MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2− Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy
- (2017) George W. Sledge et al. JOURNAL OF CLINICAL ONCOLOGY
- De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition
- (2017) Míriam Tarrado‐Castellarnau et al. Molecular Systems Biology
- Genomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole-exome sequencing
- (2017) Xi-Xi Chen et al. Nature Communications
- Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma
- (2017) Shuo Qie et al. Nature Communications
- Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors
- (2016) Shom Goel et al. CANCER CELL
- Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6
- (2016) A. Yoshida et al. CANCER RESEARCH
- Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma
- (2016) Julien Bollard et al. GUT
- Cyclin D1, cancer progression, and opportunities in cancer treatment
- (2016) Shuo Qie et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
- (2016) Robert A. Saxton et al. NATURE
- Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
- (2016) Amira Elgogary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A gene expression signature of retinoblastoma loss-of-function is a predictive biomarker of resistance to palbociclib in breast cancer cell lines and is prognostic in patients with ER positive early breast cancer
- (2016) Luca Malorni et al. Oncotarget
- FBXO4 loss facilitates carcinogen induced papilloma development in mice
- (2015) Zhaorui Lian et al. CANCER BIOLOGY & THERAPY
- Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies
- (2015) Young Joo Jeon et al. CANCER CELL
- Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs
- (2015) Y. D. Bhutia et al. CANCER RESEARCH
- Palbociclib: First Global Approval
- (2015) Sohita Dhillon DRUGS
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- PRMT5 Is Required for Lymphomagenesis Triggered by Multiple Oncogenic Drivers
- (2015) Y. Li et al. Cancer Discovery
- Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression
- (2014) Yoonjin Lee et al. NATURE
- Esophageal Carcinoma
- (2014) Anil K. Rustgi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism
- (2013) S.-M. Fendt et al. CANCER RESEARCH
- Stress eating and tuning out: Cancer cells re-wire metabolism to counter stress
- (2013) Zachary E. Stine et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Loss of RBF1 changes glutamine catabolism
- (2013) B. N. Nicolay et al. GENES & DEVELOPMENT
- ErbB2 Activation Upregulates Glutaminase 1 Expression Which Promotes Breast Cancer Cell Proliferation
- (2013) Shuo Qie et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Oesophageal carcinoma
- (2013) Arjun Pennathur et al. LANCET
- The FBXO4 Tumor Suppressor Functions as a Barrier to BrafV600E-Dependent Metastatic Melanoma
- (2013) Eric K. Lee et al. MOLECULAR AND CELLULAR BIOLOGY
- The Requirement for Cyclin D Function in Tumor Maintenance
- (2012) Yoon Jong Choi et al. CANCER CELL
- ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation
- (2012) Guoliang Qing et al. CANCER CELL
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Glutamine depletion and glucose depletion trigger growth inhibition via distinctive gene expression reprogramming
- (2012) Shuo Qie et al. CELL CYCLE
- Carbon Source Metabolism and Its Regulation in Cancer Cells
- (2012) Chengqian Yin et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism
- (2012) K. Thangavelu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Early G1 Cyclin-Dependent Kinases as Prognostic Markers and Potential Therapeutic Targets in Esophageal Adenocarcinoma
- (2011) A. Ismail et al. CLINICAL CANCER RESEARCH
- Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma
- (2010) Nan Hu et al. BMC GENOMICS
- Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase
- (2010) Priya Aggarwal et al. CANCER CELL
- Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
- (2010) Jian-Bin Wang et al. CANCER CELL
- Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply
- (2010) Andrew Y. Choo et al. MOLECULAR CELL
- Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure
- (2010) J L Dean et al. ONCOGENE
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Mutations in Fbx4 Inhibit Dimerization of the SCFFbx4 Ligase and Contribute to Cyclin D1 Overexpression in Human Cancer
- (2008) Olena Barbash et al. CANCER CELL
- Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis Are Required for Genomic Stability
- (2008) L. L. Pontano et al. MOLECULAR AND CELLULAR BIOLOGY
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now