CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

Mapping of Adenovirus of serotype 3 fibre interaction to desmoglein 2 revealed a novel ‘non-classical’ mechanism of viral receptor engagement

(2018) Emilie Vassal-Stermann et al.   Scientific Reports

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

Preclinical Safety Studies of Enadenotucirev, a Chimeric Group B Human-Specific Oncolytic Adenovirus

(2017) Sam Illingworth et al.   Molecular Therapy-Oncolytics

Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection

(2017) Rocio Garcia-Carbonero et al.   Journal for ImmunoTherapy of Cancer

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis of adhesive binding by desmocollins and desmogleins

(2016) Oliver J. Harrison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

(2016) Ray Yu-Ruei Wang et al.   eLife

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Preclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin

(2015) Maximilian Richter et al.   Molecular Therapy-Methods & Clinical Development

Structural and Functional Studies on the Interaction of Adenovirus Fiber Knobs and Desmoglein 2

(2013) H. Wang et al.   JOURNAL OF VIROLOGY

Penton-Dodecahedral Particles Trigger Opening of Intercellular Junctions and Facilitate Viral Spread during Adenovirus Serotype 3 Infection of Epithelial Cells

(2013) Zhuo-Zhuang Lu et al.   PLoS Pathogens

Impact of Human Adenovirus Type 3 Dodecahedron on Host Cells and Its Potential Role in Viral Infection

(2012) P. Fender et al.   JOURNAL OF VIROLOGY

Epithelial Junction Opener JO-1 Improves Monoclonal Antibody Therapy of Cancer

(2011) I. Beyer et al.   CANCER RESEARCH

Multimerization of Adenovirus Serotype 3 Fiber Knob Domains Is Required for Efficient Binding of Virus to Desmoglein 2 and Subsequent Opening of Epithelial Junctions

(2011) H. Wang et al.   JOURNAL OF VIROLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Oncolytic adenovirus based on serotype 3

(2010) O Hemminki et al.   CANCER GENE THERAPY

Outbreak of Acute Respiratory Infection among Infants in Lisbon, Portugal, Caused by Human Adenovirus Serotype 3 and a New 7/3 Recombinant Strain

(2010) H. Rebelo-de-Andrade et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Structure of Adenovirus Type 21 Knob in Complex with CD46 Reveals Key Differences in Receptor Contacts among Species B Adenoviruses

(2010) K. Cupelli et al.   JOURNAL OF VIROLOGY

Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14

(2010) Hongjie Wang et al.   NATURE MEDICINE

The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis

(2010) Emma C Nilsson et al.   NATURE MEDICINE

Characterization of culture-positive adenovirus serotypes from respiratory specimens in Toronto, Ontario, Canada: September 2007-June 2008.

(2009) Rani Yeung et al.   Virology Journal