Cell wall integrity signalling in human pathogenic fungi

Analysis of the essentiality ofROM2genes in the pathogenic yeastsCandida glabrataandCandida albicansusing temperature-sensitive mutants

(2015) T. Kanno et al.   JOURNAL OF APPLIED MICROBIOLOGY

Identification of Dck1 and Lmo1 as upstream regulators of the small GTPase Rho5 inSaccharomyces cerevisiae

(2015) Hans-Peter Schmitz et al.   MOLECULAR MICROBIOLOGY

The Aspergillus fumigatus pkcAG579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model

(2015) Marina Campos Rocha et al.   PLoS One

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

Disruption of the Transcriptional Regulator Cas5 Results in Enhanced Killing of Candida albicans by Fluconazole

(2014) Erin M. Vasicek et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Up against the Wall: Is Yeast Cell Wall Integrity Ensured by Mechanosensing in Plasma Membrane Microdomains?

(2014) Christian Kock et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Calcineurin-Crz1 Signaling in Lower Eukaryotes

(2014) S. Thewes   EUKARYOTIC CELL

Aspergillus fumigatusdevoid of cell wall β-1,3-glucan is viable, massively sheds galactomannan and is killed by septum formation inhibitors

(2014) Karl Dichtl et al.   MOLECULAR MICROBIOLOGY

Participation of Candida albicans Transcription Factor RLM1 in Cell Wall Biogenesis and Virulence

(2014) Yolanda Delgado-Silva et al.   PLoS One

Protein Kinase C Overexpression Suppresses Calcineurin-Associated Defects in Aspergillus nidulans and Is Involved in Mitochondrial Function

(2014) Ana Cristina Colabardini et al.   PLoS One

Cross Talk between the Cell Wall Integrity and Cyclic AMP/Protein Kinase A Pathways in Cryptococcus neoformans

(2014) M. J. Donlin et al.   mBio

Immune Evasion, Stress Resistance, and Efficient Nutrient Acquisition Are Crucial for Intracellular Survival of Candida glabrata within Macrophages

(2013) Katja Seider et al.   EUKARYOTIC CELL

Spatiotemporal regulation of Rho1 and Cdc42 activity duringCandida albicansfilamentous growth

(2013) Vincent Corvest et al.   MOLECULAR MICROBIOLOGY

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression

(2012) Sebastian Müller et al.   BMC GENOMICS

Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 Signaling Pathway in Response to Thermal Stress

(2012) Woei C. Lam et al.   EUKARYOTIC CELL

Role of the Guanine Nucleotide Exchange Factor Rom2 in Cell Wall Integrity Maintenance of Aspergillus fumigatus

(2012) Sweta Samantaray et al.   EUKARYOTIC CELL

Surface Stress Induces a Conserved Cell Wall Stress Response in the Pathogenic Fungus Candida albicans

(2012) Clemens J. Heilmann et al.   EUKARYOTIC CELL

RHO1 and RHO2 share partially overlapping functions in the regulation of cell wall integrity and hyphal polarity in Neurospora crassa

(2012) Corinna Richthammer et al.   MOLECULAR MICROBIOLOGY

Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans

(2012) Hyeseung Lee et al.   MOLECULAR MICROBIOLOGY

Deciphering cell wall integrity signalling in Aspergillus fumigatus: identification and functional characterization of cell wall stress sensors and relevant Rho GTPases

(2012) Karl Dichtl et al.   MOLECULAR MICROBIOLOGY

The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall Integrity

(2012) Sophie Lev et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Effects of Fluconazole on the Secretome, the Wall Proteome, and Wall Integrity of the Clinical Fungus Candida albicans

(2011) Alice G. Sorgo et al.   EUKARYOTIC CELL

Regulation of Cell Wall Biogenesis inSaccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway

(2011) David E. Levin   GENETICS

A Novel Specificity Protein 1 (SP1)-like Gene Regulating Protein Kinase C-1 (Pkc1)-dependent Cell Wall Integrity and Virulence Factors inCryptococcus neoformans

(2011) Amos Adler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rho1 GTPase-activating Protein CgBem2 Is Required for Survival of Azole Stress inCandida glabrata

(2011) Sapan Borah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

(2011) Radhika Jain et al.   MOLECULAR MICROBIOLOGY

Cdc42/Rho GTPases in fungi: variations on a common theme

(2011) Steven D. Harris   MOLECULAR MICROBIOLOGY

Role of the Slt2 mitogen-activated protein kinase pathway in cell wall integrity and virulence in Candida glabrata

(2010) Taiga Miyazaki et al.   FEMS YEAST RESEARCH

AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus

(2010) Franziska Dirr et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus

(2010) Karl Dichtl et al.   MOLECULAR MICROBIOLOGY

A Candida albicans cell wall-linked protein promotes invasive filamentation into semi-solid medium

(2010) Paola C. Zucchi et al.   MOLECULAR MICROBIOLOGY

Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi

(2010) Min Jin Kwon et al.   MOLECULAR MICROBIOLOGY

Characterization of Sensor-Specific Stress Response by Transcriptional Profiling of wsc1 and mid2 Deletion Strains and Chimeric Sensors in Saccharomyces cerevisiae

(2010) Clara Bermejo et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

(2010) J. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The high-osmolarity glycerol (HOG) and cell wall integrity (CWI) signalling pathways interplay: a yeast dialogue between MAPK routes

(2010) Jose Manuel Rodríguez-Peña et al.   YEAST

An Extensive Circuitry for Cell Wall Regulation in Candida albicans

(2010) Jill R. Blankenship et al.   PLoS Pathogens

PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

(2010) Shantelle L. LaFayette et al.   PLoS Pathogens

Galactofuranose attenuates cellular adhesion ofAspergillus fumigatus

(2009) Claude Lamarre et al.   CELLULAR MICROBIOLOGY

Our Paths Might Cross: the Role of the Fungal Cell Wall Integrity Pathway in Stress Response and Cross Talk with Other Stress Response Pathways

(2009) Beth Burgwyn Fuchs et al.   EUKARYOTIC CELL

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus

(2009) Vito Valiante et al.   FUNGAL GENETICS AND BIOLOGY

Candida albicansCas5, a Regulator of Cell Wall Integrity, Is Required for Virulence in Murine andTollMutant Fly Models

(2009) Georgios Chamilos et al.   JOURNAL OF INFECTIOUS DISEASES

PKC1Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic FungusCryptococcus neoformans

(2008) Kimberly J. Gerik et al.   EUKARYOTIC CELL

A small G protein Rhb1 and a GTPase-activating protein Tsc2 involved in nitrogen starvation-induced morphogenesis and cell wall integrity of Candida albicans

(2008) Chang-Chih Tsao et al.   FUNGAL GENETICS AND BIOLOGY

Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

(2008) Louise A. Walker et al.   PLoS Pathogens

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response

(2007) Vito Valiante et al.   FUNGAL GENETICS AND BIOLOGY