Fanconi anemia protein FANCI functions in ribosome biogenesis

A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination

(2017) Winnie Tan et al.   EXPERIMENTAL HEMATOLOGY

Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia

(2017) Kerstin Knies et al.   JOURNAL OF CLINICAL INVESTIGATION

Crosstalk between the nucleolus and the DNA damage response

(2017) L. M. Ogawa et al.   Molecular BioSystems

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

(2017) Sylvie van Twest et al.   MOLECULAR CELL

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response

(2017) Elizabeth L. Thompson et al.   NUCLEIC ACIDS RESEARCH

The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner

(2017) Swaathi Jayaraman et al.   NUCLEIC ACIDS RESEARCH

SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner

(2017) Deokjae Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomopathies: There’s strength in numbers

(2017) Eric W. Mills et al.   SCIENCE

Fanconi Anemia Proteins Function in Mitophagy and Immunity

(2016) Rhea Sumpter et al.   CELL

Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway

(2016) David Lopez-Martinez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nucleolar organizer regions: genomic ‘dark matter’ requiring illumination

(2016) Brian McStay   GENES & DEVELOPMENT

Biallelic inactivation of REV7 is associated with Fanconi anemia

(2016) Dominique Bluteau et al.   JOURNAL OF CLINICAL INVESTIGATION

The Fanconi anaemia pathway: new players and new functions

(2016) Raphael Ceccaldi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

(2016) Emilien Nicolas et al.   Nature Communications

The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription

(2016) Rebecca Johnston et al.   Oncotarget

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair

(2016) Elizabeth A. Vuono et al.   Scientific Reports

Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets

(2016) Eric W. Mills et al.   Cell Reports

SnapShot: Fanconi Anemia and Associated Proteins

(2015) Anderson T. Wang et al.   CELL

Determinants of mammalian nucleolar architecture

(2015) Katherine I. Farley et al.   CHROMOSOMA

Lentiviral-Mediated Gene Therapy in Fanconi Anemia-A Mice Reveals Long-Term Engraftment and Continuous Turnover of Corrected HSCs

(2015) F. Molina-Estevez et al.   CURRENT GENE THERAPY

Ribosomopathies: how a common root can cause a tree of pathologies

(2015) Nadia Danilova et al.   Disease Models & Mechanisms

Functional divergence of eukaryotic RNA polymerases: Unique properties of RNA polymerase I suit its cellular role

(2015) Olga V. Viktorovskaya et al.   GENE

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

(2015) Rebekka A. Schwab et al.   MOLECULAR CELL

A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage

(2015) X Chen et al.   ONCOGENE

Fanconi anemia (FA) and crosslinker sensitivity: Re-appraising the origins of FA definition

(2015) Giovanni Pagano et al.   PEDIATRIC BLOOD & CANCER

Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells

(2015) Lukas Badertscher et al.   Cell Reports

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2

(2015) Maria Castella et al.   PLoS Genetics

Nucleolar stress in Diamond Blackfan anemia pathophysiology

(2014) Steven R. Ellis   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Stress and DNA repair biology of the Fanconi anemia pathway

(2014) S. Longerich et al.   BLOOD

Marrow failure: a window into ribosome biology

(2014) D. Ruggero et al.   BLOOD

Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth

(2014) Sylvia Koch et al.   CELL CYCLE

Variable Clinical Presentation of Shwachman–Diamond Syndrome: Update from the North American Shwachman–Diamond Syndrome Registry

(2014) Kasiani C. Myers et al.   JOURNAL OF PEDIATRICS

Hypoxic Stress Facilitates Acute Activation and Chronic Downregulation of Fanconi Anemia Proteins

(2014) Susan E. Scanlon et al.   MOLECULAR CANCER RESEARCH

Two orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesis

(2014) Minshi Wang et al.   NUCLEIC ACIDS RESEARCH

Biallelic Mutations in BRCA1 Cause a New Fanconi Anemia Subtype

(2014) Sarah L. Sawyer et al.   Cancer Discovery

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

The nucleolus—guardian of cellular homeostasis and genome integrity

(2013) Ingrid Grummt   CHROMOSOMA

Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing

(2013) Katherine E. Sloan et al.   JOURNAL OF CELL BIOLOGY

The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders

(2013) David M. Raiser et al.   LEUKEMIA & LYMPHOMA

The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

(2013) Lionel Tafforeau et al.   MOLECULAR CELL

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

(2013) Molly C. Kottemann et al.   NATURE

The Inherited Bone Marrow Failure Syndromes

(2013) S. Deborah Chirnomas et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal

(2013) Rebecca A. Boisvert et al.   PLoS One

Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein

(2012) M. A. Rego et al.   BLOOD

Recent insights into inherited bone marrow failure syndromes

(2012) Shefali Parikh et al.   CURRENT OPINION IN PEDIATRICS

Bleach gel: A simple agarose gel for analyzing RNA quality

(2012) Patrick S. Aranda et al.   ELECTROPHORESIS

Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions

(2012) Sylvie Urbé et al.   MOLECULAR BIOLOGY OF THE CELL

The Human Base Excision Repair Enzyme SMUG1 Directly Interacts with DKC1 and Contributes to RNA Quality Control

(2012) Laure Jobert et al.   MOLECULAR CELL

The genetics of dyskeratosis congenita

(2012) Philip J. Mason et al.   Cancer Genetics

NOL11, Implicated in the Pathogenesis of North American Indian Childhood Cirrhosis, Is Required for Pre-rRNA Transcription and Processing

(2012) Emily F. Freed et al.   PLoS Genetics

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

(2011) S. A. Williams et al.   BLOOD

Nuclear ErbB2 Enhances Translation and Cell Growth by Activating Transcription of Ribosomal RNA Genes

(2011) L.-Y. Li et al.   CANCER RESEARCH

Ubiquitylation and the Fanconi anemia pathway

(2011) Elizabeth Garner et al.   FEBS LETTERS

Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome

(2011) A. J. Finch et al.   GENES & DEVELOPMENT

BLM helicase facilitates RNA polymerase I-mediated ribosomal RNA transcription

(2011) Patrick M. Grierson et al.   HUMAN MOLECULAR GENETICS

Proteomic profiling of the human T-cell nucleolus

(2011) Mohamed Ali Jarboui et al.   MOLECULAR IMMUNOLOGY

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor

(2011) M A Rego et al.   ONCOGENE

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

(2011) Woo Joo et al.   SCIENCE

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair

(2010) L. Colnaghi et al.   BLOOD

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies

(2010) P. Sharma et al.   JOURNAL OF CELL SCIENCE

Efficient extraction of nucleolar proteins for interactome analyses

(2010) Delphine Chamousset et al.   PROTEOMICS

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

Identification and analysis of new proteins involved in the DNA damage response network of Fanconi anemia and Bloom syndrome

(2009) Rong Guo et al.   METHODS

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

(2009) C. Vascotto et al.   MOLECULAR AND CELLULAR BIOLOGY

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

(2008) Masamichi Ishiai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NOPdb: Nucleolar Proteome Database--2008 update

(2008) Y. Ahmad et al.   NUCLEIC ACIDS RESEARCH