Stimulated hepatic stellate cell promotes progression of hepatocellular carcinoma due to protein kinase R activation
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Stimulated hepatic stellate cell promotes progression of hepatocellular carcinoma due to protein kinase R activation
Authors
Keywords
Hepatocellular carcinoma, Small interfering RNAs, Cytokines, Reverse transcriptase-polymerase chain reaction, Inflammation, Cytotoxicity assay, Nonalcoholic steatohepatitis, Phosphorylation
Journal
PLoS One
Volume 14, Issue 2, Pages e0212589
Publisher
Public Library of Science (PLoS)
Online
2019-02-23
DOI
10.1371/journal.pone.0212589
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Roles of protein kinase R in cancer: Potential as a therapeutic target
- (2018) Takao Watanabe et al. CANCER SCIENCE
- MicroRNA-146a-5p attenuates irradiation-induced and LPS-induced hepatic stellate cell activation and hepatocyte apoptosis through inhibition of TLR4 pathway
- (2018) Yuhan Chen et al. Cell Death & Disease
- Upregulated absorption of dietary palmitic acids with changes in intestinal transporters in non-alcoholic steatohepatitis (NASH)
- (2017) Hiroki Utsunomiya et al. JOURNAL OF GASTROENTEROLOGY
- Hepatic stellate cell activation and pro-fibrogenic signals
- (2017) Chandrashekhar R. Gandhi JOURNAL OF HEPATOLOGY
- Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial
- (2017) Paul M Ridker et al. LANCET
- Palmitic acid elicits hepatic stellate cell activation through inflammasomes and hedgehog signaling
- (2017) Na-Na Duan et al. LIFE SCIENCES
- Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β
- (2017) Dequina A. Nicholas et al. PLoS One
- DSS colitis promotes tumorigenesis and fibrogenesis in a choline-deficient high-fat diet-induced NASH mouse model
- (2016) Koichi Achiwa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Role of Interleukin-1 in Inflammatory and Malignant Human Skin Diseases and the Rationale for Targeting Interleukin-1 Alpha
- (2016) Mayassa J. Bou-Dargham et al. MEDICINAL RESEARCH REVIEWS
- p58IPK suppresses NLRP3 inflammasome activation and IL-1β production via inhibition of PKR in macrophages
- (2016) Evgenii Boriushkin et al. Scientific Reports
- Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells
- (2016) Sacha Robert et al. PLoS One
- Interleukin-1β/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis
- (2015) Bo Su et al. HEPATOLOGY
- MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR Activator PACT in Human Hepatic Stellate Cells
- (2015) Masato Nakamura et al. PLoS One
- Clinical characteristics, treatment, and prognosis of non-B, non-C hepatocellular carcinoma: a large retrospective multicenter cohort study
- (2014) Ryosuke Tateishi et al. JOURNAL OF GASTROENTEROLOGY
- Stellate cells and the development of liver cancer: Therapeutic potential of targeting the stroma
- (2014) Cédric Coulouarn et al. JOURNAL OF HEPATOLOGY
- Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation
- (2014) Wen Liang et al. LABORATORY INVESTIGATION
- Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever
- (2014) Vinicio Carloni et al. LIVER INTERNATIONAL
- Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma
- (2013) Virginia Hernandez–Gea et al. GASTROENTEROLOGY
- Protein Kinase R Modulates c-Fos and c-Jun Signaling to Promote Proliferation of Hepatocellular Carcinoma with Hepatitis C Virus Infection
- (2013) Takao Watanabe et al. PLoS One
- IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease
- (2013) Amina A. Negash et al. PLoS Pathogens
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
- (2011) G. Vernon et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma
- (2011) Qiang Gao et al. CANCER SCIENCE
- Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
- (2011) Timea Csak et al. HEPATOLOGY
- DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH
- (2011) Erwin Gäbele et al. JOURNAL OF HEPATOLOGY
- Sorafenib: Where do we go from here?
- (2010) Abby B. Siegel et al. HEPATOLOGY
- Toll-like Receptor 4 and Hepatic Fibrogenesis
- (2010) Jean-Philippe Pradere et al. SEMINARS IN LIVER DISEASE
- Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
- (2008) Scott L. Friedman PHYSIOLOGICAL REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More