DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity

Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors

(2012) Susanne H. Sheehy et al.   PLoS One

Protective CD8+ T lymphocytes in Primates Immunized with Malaria Sporozoites

(2012) Walter R. Weiss et al.   PLoS One

Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites

(2011) Noah S. Butler et al.   Cell Host & Microbe

New Japanese encephalitis vaccines: alternatives to production in mouse brain

(2011) Scott B Halstead et al.   Expert Review of Vaccines

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host

(2011) Alida Coppi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

(2011) Meta Roestenberg et al.   LANCET

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Adenovirus 5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part A: Safety and Immunogenicity in Seronegative Adults

(2011) Martha Sedegah et al.   PLoS One

Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component

(2011) Cindy Tamminga et al.   PLoS One

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity

(2011) J. E. Epstein et al.   SCIENCE

Current strategies for subunit and genetic viral veterinary vaccine development

(2011) Alejandro Brun et al.   VIRUS RESEARCH

The Th1 Immune Response to Plasmodium falciparum Circumsporozoite Protein Is Boosted by Adenovirus Vectors 35 and 26 with a Homologous Insert

(2010) K. Radosevic et al.   Clinical and Vaccine Immunology

Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses

(2010) Richard A. Koup et al.   PLoS One

Regulatory T Cells Suppress Natural Killer Cells during Plasmid DNA Vaccination in Mice, Blunting the CD8+ T Cell Immune Response by the Cytokine TGFβ

(2010) Kwesi Frimpong-Boateng et al.   PLoS One

Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa

(2010) Walter Jaoko et al.   PLoS One

Safety and Immunogenicity of a Replication-Defective Adenovirus Type 5 HIV Vaccine in Ad5-Seronegative Persons: A Randomized Clinical Trial (HVTN 054)

(2010) Laurence Peiperl et al.   PLoS One

DNA vaccines in veterinary use

(2009) Laurel Redding et al.   Expert Review of Vaccines

Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8+ T-Cell Responses

(2009) A. Reyes-Sandoval et al.   INFECTION AND IMMUNITY

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

(2009) Kent E. Kester et al.   JOURNAL OF INFECTIOUS DISEASES

Comparative Cell‐Mediated Immunogenicity of DNA/DNA, DNA/Adenovirus Type 5 (Ad5), or Ad5/Ad5 HIV‐1 Clade BgagVaccine Prime‐Boost Regimens

(2009) David M. Asmuth et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data

(2009) Vasee S Moorthy et al.   MALARIA JOURNAL

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

(2009) George Jiang et al.   PLoS One

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES

Protective CD8+T cells againstPlasmodiumliver stages: immunobiology of an ‘unnatural’ immune response

(2008) Michael Glen Overstreet et al.   IMMUNOLOGICAL REVIEWS

Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort

(2008) Thomas A Gaziano et al.   LANCET

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research

(2008) Kent E. Kester et al.   VACCINE