Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus

Inflammasomes in stroke: a triggering role for acid-sensing ion channels

(2018) Kanchan Vats et al.   Annals of the New York Academy of Sciences

Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway

(2018) Rui Lan et al.   BRAIN RESEARCH BULLETIN

Mitochondrial dynamics: overview of molecular mechanisms

(2018) Lisa Tilokani et al.   Essays in Biochemistry

Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway

(2018) Pan Tang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice

(2018) Tian Wang et al.   Journal of Neuroinflammation

Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment

(2018) Zhi Wang et al.   Journal of Neuroinflammation

Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats

(2018) Ya-Lin Wang et al.   Journal of Neuroinflammation

Supplementation of lycopene attenuates lipopolysaccharide-induced amyloidogenesis and cognitive impairments via mediating neuroinflammation and oxidative stress

(2018) Jia Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Honokiol ameliorates cognitive impairment by attenuating amyloidosis and neuroinflammation in a transgenic mouse model of Alzheimer's disease

(2018) DONGMEI WANG et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mitophagy and the release of inflammatory cytokines

(2018) James Harris et al.   MITOCHONDRION

Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases

(2018) Charleen T. Chu   NEUROBIOLOGY OF DISEASE

Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury

(2018) Xin Xu et al.   NEUROBIOLOGY OF DISEASE

Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1-Nrf2 Signaling Pathway

(2018) Bin Zhang et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial bioenergetics, redox state, dynamics and turnover alterations in renal mass reduction models of chronic kidney diseases and their possible implications in the progression of this illness

(2018) Omar Emiliano Aparicio-Trejo et al.   PHARMACOLOGICAL RESEARCH

Sirt3 Ameliorates Oxidative Stress and Mitochondrial Dysfunction After Intracerebral Hemorrhage in Diabetic Rats

(2018) Jingwei Zheng et al.   Frontiers in Neuroscience

Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis

(2018) Qingling Guo et al.   Frontiers in Immunology

SIRT3 activator honokiol ameliorates surgery/anesthesia-induced cognitive decline in mice through anti-oxidative stress and anti-inflammatory in hippocampus

(2018) Ji-Shi Ye et al.   CNS Neuroscience & Therapeutics

Cognitive decline after major oncological surgery in the elderly

(2017) M. Plas et al.   EUROPEAN JOURNAL OF CANCER

Cognitive Impairment and Overall Survival in Frail Surgical Patients

(2017) Salima S. Makhani et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation

(2017) Tiantian Tang et al.   Nature Communications

Critical role of matrix metallopeptidase 9 in postoperative cognitive dysfunction and age-dependent cognitive decline

(2017) Jiangjiang Bi et al.   Oncotarget

Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation

(2017) Shenglong Cao et al.   Scientific Reports

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

(2016) Min-Ji Kim et al.   Autophagy

Mitophagy: a balance regulator of NLRP3 inflammasome activation

(2016) Min-Ji Kim et al.   BMB Reports

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

(2016) Zhenyu Zhong et al.   CELL

Rapamycin Protects Sepsis-Induced Cognitive Impairment in Mouse Hippocampus by Enhancing Autophagy

(2016) Wenyu Liu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice

(2016) Ashok Jangra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy

(2016) Chao Lin et al.   JOURNAL OF PINEAL RESEARCH

Caspase-1 Deficiency Alleviates Dopaminergic Neuronal Death via Inhibiting Caspase-7/AIF Pathway in MPTP/p Mouse Model of Parkinson’s Disease

(2016) Chen Qiao et al.   MOLECULAR NEUROBIOLOGY

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

(2016) Yuan He et al.   NATURE

Surgery-Induced Hippocampal Angiotensin II Elevation Causes Blood-Brain Barrier Disruption via MMP/TIMP in Aged Rats

(2016) Zhengqian Li et al.   Frontiers in Cellular Neuroscience

Honokiol improves learning and memory impairments induced by scopolamine in mice

(2015) Yan-Fang Xian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Sustained increase in α5GABAA receptor function impairs memory after anesthesia

(2014) Agnieszka A. Zurek et al.   JOURNAL OF CLINICAL INVESTIGATION