Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1–3 family
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Title
Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1–3 family
Authors
Keywords
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Journal
GENES & DEVELOPMENT
Volume 31, Issue 7, Pages 674-687
Publisher
Cold Spring Harbor Laboratory
Online
2017-04-27
DOI
10.1101/gad.296301.117
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Note: Only part of the references are listed.- SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b
- (2016) Sita Kugel et al. CELL
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- (2016) Thales Papagiannakopoulos et al. Cell Metabolism
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- (2016) S Manier et al. LEUKEMIA
- Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma
- (2016) John T. Powers et al. NATURE
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- (2016) Bianca Busch et al. NUCLEIC ACIDS RESEARCH
- The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing
- (2016) Nils Degrauwe et al. Cell Reports
- IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC
- (2016) Hanane Ennajdaoui et al. Cell Reports
- Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival
- (2016) Anne E. Conway et al. Cell Reports
- Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements
- (2016) Sara J.C. Gosline et al. Cell Reports
- Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors
- (2015) Amy L. Walz et al. CANCER CELL
- Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors
- (2015) Jenny Wegert et al. CANCER CELL
- Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis
- (2015) Carman Man-Chung Li et al. GENES & DEVELOPMENT
- IMP-3 Promotes Migration and Invasion of Melanoma Cells by Modulating the Expression of HMGA2 and Predicts Poor Prognosis in Melanoma
- (2015) Yi-Shuan Sheen et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- RecurrentDICER1hotspot mutations in endometrial tumours and their impact on microRNA biogenesis
- (2015) Jiamin Chen et al. JOURNAL OF PATHOLOGY
- Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation
- (2015) Asaf Rotem et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development
- (2015) N. Dimitrova et al. Cancer Discovery
- IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer
- (2015) Keisuke Taniuchi et al. Oncotarget
- Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations
- (2014) Leanne de Kock et al. ACTA NEUROPATHOLOGICA
- Lin28b Is Sufficient to Drive Liver Cancer and Necessary for Its Maintenance in Murine Models
- (2014) Liem H. Nguyen et al. CANCER CELL
- Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition
- (2014) Andrew D. Bosson et al. MOLECULAR CELL
- Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours
- (2014) Dinesh Rakheja et al. Nature Communications
- IMP3 RNP Safe Houses Prevent miRNA-Directed HMGA2 mRNA Decay in Cancer and Development
- (2014) Lars Jønson et al. Cell Reports
- LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7
- (2013) B. B. Madison et al. GENES & DEVELOPMENT
- Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts
- (2013) A. M. Gurtan et al. GENES & DEVELOPMENT
- IMP3 Protein Promotes Chemoresistance in Breast Cancer Cells by Regulating Breast Cancer Resistance Protein (ABCG2) Expression
- (2013) Sanjoy Samanta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition
- (2013) M. Hafner et al. RNA
- A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties
- (2013) Jinsuke Nishino et al. eLife
- Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1
- (2012) Arvind Ravi et al. CANCER CELL
- Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?
- (2012) Jessica L. Bell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails
- (2012) J. E. Wilusz et al. GENES & DEVELOPMENT
- IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling
- (2012) N. Stohr et al. GENES & DEVELOPMENT
- Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
- (2012) M. Janiszewska et al. GENES & DEVELOPMENT
- LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
- (2012) Jan J Molenaar et al. NATURE GENETICS
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Molecular signatures database (MSigDB) 3.0
- (2011) A. Liberzon et al. BIOINFORMATICS
- The Lin28/let-7 Axis Regulates Glucose Metabolism
- (2011) Hao Zhu et al. CELL
- Extending the phenotypes associated withDICER1mutations
- (2011) William D. Foulkes et al. HUMAN MUTATION
- MicroRNAs can generate thresholds in target gene expression
- (2011) Shankar Mukherji et al. NATURE GENETICS
- Recurrent SomaticDICER1Mutations in Nonepithelial Ovarian Cancers
- (2011) Alireza Heravi-Moussavi et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells
- (2010) Sonia A. Melo et al. CANCER CELL
- Germline DICER1 mutations and familial cystic nephroma
- (2010) A. Bahubeshi et al. JOURNAL OF MEDICAL GENETICS
- MicroRNA Functions in Stress Responses
- (2010) Anthony K.L. Leung et al. MOLECULAR CELL
- Differential expression analysis for sequence count data
- (2010) Simon Anders et al. GENOME BIOLOGY
- An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
- (2009) Dimitrios Iliopoulos et al. CELL
- MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells
- (2009) Na Xu et al. CELL
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- MicroRNAs and Cancer: Short RNAs Go a Long Way
- (2009) Andrea Ventura et al. CELL
- Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
- (2009) Christine Mayr et al. CELL
- The role of let-7 in cell differentiation and cancer
- (2009) Benjamin Boyerinas et al. ENDOCRINE-RELATED CANCER
- Dicer1 functions as a haploinsufficient tumor suppressor
- (2009) M. S. Kumar et al. GENES & DEVELOPMENT
- Lin28 promotes transformation and is associated with advanced human malignancies
- (2009) Srinivas R Viswanathan et al. NATURE GENETICS
- A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
- (2009) Sonia A Melo et al. NATURE GENETICS
- Small silencing RNAs: an expanding universe
- (2009) Megha Ghildiyal et al. NATURE REVIEWS GENETICS
- DICER1 Mutations in Familial Pleuropulmonary Blastoma
- (2009) D. A. Hill et al. SCIENCE
- Identification of Let-7-Regulated Oncofetal Genes
- (2008) B. Boyerinas et al. CANCER RESEARCH
- The impact of microRNAs on protein output
- (2008) Daehyun Baek et al. NATURE
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- Selective Blockade of MicroRNA Processing by Lin28
- (2008) S. R. Viswanathan et al. SCIENCE
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