Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

(2017) Suhas V Vasaikar et al.   NUCLEIC ACIDS RESEARCH

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors

(2016) Ming Liu et al.   HEPATOLOGY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes

(2015) Han-Jin Park et al.   PLoS One

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

(2014) F. Nakahara et al.   BLOOD

Wnt–Notch signalling crosstalk in development and disease

(2014) Giovanna M. Collu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hepatic Notch Signaling Correlates With Insulin Resistance and Nonalcoholic Fatty Liver Disease

(2013) L. Valenti et al.   DIABETES

Lef1 Contributes to the Differentiation of Bulge Stem Cells by Nuclear Translocation and Cross-Talk with the Notch Signaling Pathway

(2013) Yi Zhang et al.   International Journal of Medical Sciences

Cancer Stem Cells: Current Status and Evolving Complexities

(2012) Jane E. Visvader et al.   Cell Stem Cell

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

(2012) Sayaka Sekiya et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Implications of Cancer Stem Cell Biology in Hepatocellular Carcinoma

(2012) Junfang Ji et al.   SEMINARS IN ONCOLOGY

The Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells

(2011) Jonas Ungerbäck et al.   PLoS One

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion

(2010) L. Chen et al.   GUT

Survival in Asian Americans After Treatments for Hepatocellular Carcinoma

(2010) Myron J. Tong et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients

(2010) Leilei Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute  -Secretase Inhibition of Nonhuman Primate CNS Shifts Amyloid Precursor Protein (APP) Metabolism from Amyloid-  Production to Alternative APP Fragments without Amyloid-  Rebound

(2010) J. J. Cook et al.   JOURNAL OF NEUROSCIENCE

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival

(2009) Leilei Chen et al.   HEPATOLOGY

Liver stem cells and hepatocellular carcinoma

(2008) Lopa Mishra et al.   HEPATOLOGY

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

(2008) Konstantin Petropoulos et al.   JOURNAL OF EXPERIMENTAL MEDICINE