CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

(2014) Supriya K. Saha et al.   NATURE

Hepatic stem cell niches

(2013) Claus Kordes et al.   JOURNAL OF CLINICAL INVESTIGATION

Poly(ADP-ribose) polymerase 1 regulates nuclear reprogramming and promotes iPSC generation without c-Myc

(2013) Shih-Hwa Chiou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chromatin modifiers and remodellers: regulators of cellular differentiation

(2013) Taiping Chen et al.   NATURE REVIEWS GENETICS

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

(2012) Graziano Martello et al.   Cell Stem Cell

Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma

(2012) Xiaodong Guo et al.   Diagnostic Pathology

SPOCK1 Is Regulated by CHD1L and Blocks Apoptosis and Promotes HCC Cell Invasiveness and Metastasis in Mice

(2012) Yan Li et al.   GASTROENTEROLOGY

The chromatin remodeling factor Chd1l is required in the preimplantation embryo

(2012) A. C. Snider et al.   Biology Open

Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development

(2011) Tim Hon Man Chan et al.   HEPATOLOGY

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion

(2010) L. Chen et al.   GUT

CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients

(2010) Leilei Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

The Incidence and Epidemiology of Hepatocellular Carcinoma: A Global and Regional Perspective

(2010) A. P. Venook et al.   ONCOLOGIST

CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

(2010) Michael P. Schnetz et al.   PLoS Genetics

Hijacking the Chromatin Remodeling Machinery: Impact of SWI/SNF Perturbations in Cancer

(2009) B. Weissman et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival

(2009) Leilei Chen et al.   HEPATOLOGY

Transgenic CHD1L Expression in Mouse Induces Spontaneous Tumors

(2009) Muhan Chen et al.   PLoS One

Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1

(2009) D. Ahel et al.   SCIENCE

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

Global Transcription in Pluripotent Embryonic Stem Cells

(2008) Sol Efroni et al.   Cell Stem Cell

Liver stem cells and hepatocellular carcinoma

(2008) Lopa Mishra et al.   HEPATOLOGY