Immune mechanisms of salt-sensitive hypertension and renal end-organ damage

Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-β1a subunit (CACNB1)

(2018) Claudio F. Perez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide

(2018) Roxana Loperena et al.   CARDIOVASCULAR RESEARCH

Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association

(2018) Emelia J. Benjamin et al.   CIRCULATION

Under Pressure

(2018) Sabine Kossmann et al.   HYPERTENSION

Myeloid CD11c+Antigen-Presenting Cells Ablation Prevents Hypertension in Response to Angiotensin II Plus High-Salt DietNovelty and Significance

(2018) Daniel Hevia et al.   HYPERTENSION

Increased Perfusion Pressure Drives Renal T-Cell Infiltration in the Dahl Salt-Sensitive RatNovelty and Significance

(2017) Louise C. Evans et al.   HYPERTENSION

The immunology of hypertension

(2017) Allison E. Norlander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension

(2017) Natalia R. Barbaro et al.   Cell Reports

Potential US Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline

(2017) Paul Muntner et al.   CIRCULATION

Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron

(2016) Jiandong Zhang et al.   Cell Metabolism

Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular DysfunctionClinical Perspective

(2016) Lei Wang et al.   CIRCULATION

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive StimuliNovelty and Significance

(2016) Hana A. Itani et al.   CIRCULATION RESEARCH

Activation of Human T Cells in HypertensionNovelty and Significance

(2016) Hana A. Itani et al.   HYPERTENSION

Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II–Induced HypertensionNovelty and Significance

(2016) Allison E. Norlander et al.   HYPERTENSION

Salt Sensitivity of Blood Pressure

(2016) Fernando Elijovich et al.   HYPERTENSION

Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses

(2016) Muhammad Oneeb Rehman Mian et al.   JOURNAL OF HYPERTENSION

Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus

(2016) Michaela Finsterbusch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Interleukin-1 beta to Suppress Sympathoexcitation in Hypothalamic Paraventricular Nucleus in Dahl Salt-Sensitive Hypertensive Rats

(2015) Jie Qi et al.   Cardiovascular Toxicology

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

(2015) Jonathan Jantsch et al.   Cell Metabolism

Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in HypertensionNovelty and Significance

(2015) Kandarp H. Shah et al.   CIRCULATION RESEARCH

Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia

(2015) J. H. Southcombe et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Associations of Soluble CD14 and Endotoxin with Mortality, Cardiovascular Disease, and Progression of Kidney Disease among Patients with CKD

(2015) R. Poesen et al.   Clinical Journal of the American Society of Nephrology

Renal Transporter Activation During Angiotensin-II Hypertension is Blunted in Interferon-γ−/−and Interleukin-17A−/−MiceNovelty and Significance

(2015) Nikhil V. Kamat et al.   HYPERTENSION

Obligatory Role for B Cells in the Development of Angiotensin II–Dependent HypertensionNovelty and Significance

(2015) Christopher T. Chan et al.   HYPERTENSION

Mutation of SH2B3 (LNK), a Genome-Wide Association Study Candidate for Hypertension, Attenuates Dahl Salt-Sensitive Hypertension via Inflammatory Modulation

(2015) N. P. Rudemiller et al.   HYPERTENSION

Decreased proportion of Foxp3+CD4+ regulatory T cells contributes to the development of hypertension in genetically hypertensive rats

(2015) Masato Katsuki et al.   JOURNAL OF HYPERTENSION

Hypertension

(2015) Neil R Poulter et al.   LANCET

Effects of dietary salt levels on monocytic cells and immune responses in healthy human subjects: a longitudinal study

(2015) Buqing Yi et al.   Translational Research

Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart

(2014) Toan Pham et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sodium balance is not just a renal affair

(2014) Jens Titze   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Molecular Mechanisms of Renal Blood Flow Autoregulation

(2014) Marilyn Burke et al.   Current Vascular Pharmacology

Oligoclonal CD8 + T Cells Play a Critical Role in the Development of Hypertension

(2014) Daniel W. Trott et al.   HYPERTENSION

Tumor Necrosis Factor-α Produced in the Kidney Contributes to Angiotensin II–dependent Hypertension

(2014) Jiandong Zhang et al.   HYPERTENSION

The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

(2014) Daniela Carnevale et al.   IMMUNITY

DC isoketal-modified proteins activate T cells and promote hypertension

(2014) Annet Kirabo et al.   JOURNAL OF CLINICAL INVESTIGATION

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

(2014) Eleni Rapsomaniki et al.   LANCET

Sodium chloride, SGK1, and Th17 activation

(2014) Katrina J. Binger et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Reactive Oxygen Species, Vascular Noxs, and Hypertension: Focus on Translational and Clinical Research

(2013) Augusto C. Montezano et al.   ANTIOXIDANTS & REDOX SIGNALING

An Update on Immune System Activation in the Pathogenesis of Hypertension

(2013) Michael J. Ryan   HYPERTENSION

Immunosenescent CD8 + T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension

(2013) Jong-Chan Youn et al.   HYPERTENSION

CD247 Modulates Blood Pressure by Altering T-Lymphocyte Infiltration in the Kidney

(2013) Nathan Rudemiller et al.   HYPERTENSION

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Autoimmunity in the pathogenesis of hypertension

(2013) Bernardo Rodríguez-Iturbe et al.   Nature Reviews Nephrology

Toll-like receptor 4 signaling regulates the acute local inflammatory response to injury and the fibrosis/neovascularization of sterile wounds

(2013) Samielle K. Brancato et al.   WOUND REPAIR AND REGENERATION

A novel in vitro model system for smooth muscle differentiation from human embryonic stem cell-derived mesenchymal cells

(2012) Xia Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Synapses, Signals, CDs, and Cytokines

(2012) Meena S. Madhur et al.   CIRCULATION RESEARCH

Neural reflexes in inflammation and immunity

(2012) Ulf Andersson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

(2012) Sapna Devi et al.   NATURE MEDICINE

Natural Regulatory T Cells Control Coronary Arteriolar Endothelial Dysfunction in Hypertensive Mice

(2011) Khalid Matrougui et al.   AMERICAN JOURNAL OF PATHOLOGY

The adaptor Lnk (SH2B3): An emerging regulator in vascular cells and a link between immune and inflammatory signaling

(2011) Julie Devallière et al.   BIOCHEMICAL PHARMACOLOGY

Gene polymorphisms contributing to hypertension in immunoglobulin A nephropathy

(2011) Maki Shinzawa et al.   Clinical and Experimental Nephrology

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

(2011) Ervin R. Fox et al.   HUMAN MOLECULAR GENETICS

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension

(2010) Antony Vinh et al.   CIRCULATION

Central and Peripheral Mechanisms of T-Lymphocyte Activation and Vascular Inflammation Produced by Angiotensin II–Induced Hypertension

(2010) Paul J. Marvar et al.   CIRCULATION RESEARCH

Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension

(2010) Bernardo Rodriguez-Iturbe   Clinical and Experimental Nephrology

T lymphocytes: a role in hypertension?

(2010) Ernesto L Schiffrin   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Ribonucleic Acid Interference Knockdown of Interleukin 6 Attenuates Cold-Induced Hypertension

(2010) Patrick Crosswhite et al.   HYPERTENSION

Tumor Necrosis Factor-α Antagonist Etanercept Decreases Blood Pressure and Protects the Kidney in a Mouse Model of Systemic Lupus Erythematosus

(2010) Marcia Venegas-Pont et al.   HYPERTENSION

High Dietary Protein Exacerbates Hypertension and Renal Damage in Dahl SS Rats by Increasing Infiltrating Immune Cells in the Kidney

(2010) Carmen De Miguel et al.   HYPERTENSION

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study

(2009) Georg B Ehret et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Protective Importance of the Myogenic Response in the Renal Circulation

(2009) Anil K. Bidani et al.   HYPERTENSION

Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure

(2009) Amanda J. Rickard et al.   HYPERTENSION

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

A Role for Angiotensin II Type 1 Receptors on Bone Marrow-Derived Cells in the Pathogenesis of Angiotensin II–Dependent Hypertension

(2009) Steven D. Crowley et al.   HYPERTENSION

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

(2009) Aron M. Geurts et al.   SCIENCE

Associations of Glomerular Number and Birth Weight With Clinicopathological Features of African Americans and Whites

(2008) Michael D. Hughson et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Thrombin-induced endothelial barrier disruption in intact microvessels: role of RhoA/Rho kinase-myosin phosphatase axis

(2008) G. P. van Nieuw Amerongen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Gender difference in blood pressure responses to dietary sodium intervention in the GenSalt study

(2008) Jiang He et al.   JOURNAL OF HYPERTENSION

High Perfusion Pressure Accelerates Renal Injury in Salt-Sensitive Hypertension

(2008) T. Mori et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteasomal Processing of Albumin by Renal Dendritic Cells Generates Antigenic Peptides

(2008) D. Macconi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY