DNA nanodevices map enzymatic activity in organelles

Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule

(2018) Aneesh T. Veetil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A DNA-based fluorescent reporter maps HOCl production in the maturing phagosome

(2018) Shareefa Thekkan et al.   Nature Chemical Biology

A pH-correctable, DNA-based fluorescent reporter for organellar calcium

(2018) Nagarjun Narayanaswamy et al.   NATURE METHODS

A DNA nanomachine chemically resolves lysosomes in live cells

(2018) KaHo Leung et al.   Nature Nanotechnology

Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules

(2017) Aneesh T. Veetil et al.   Nature Nanotechnology

High lumenal chloride in the lysosome is critical for lysosome function

(2017) Kasturi Chakraborty et al.   eLife

Nucleic Acid–Based Nanodevices in Biological Imaging

(2016) Kasturi Chakraborty et al.   Annual Review of Biochemistry

An ERp57-mediated disulphide exchange promotes the interaction between Burkholderia cenocepacia and epithelial respiratory cells

(2016) Francesca Pacello et al.   Scientific Reports

Nutrient-sensing mechanisms and pathways

(2015) Alejo Efeyan et al.   NATURE

A pH-independent DNA nanodevice for quantifying chloride transport in organelles of living cells

(2015) Sonali Saha et al.   Nature Nanotechnology

A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red

(2014) Efthymia Prifti et al.   ACS Chemical Biology

An Activatable Theranostic for Targeted Cancer Therapy and Imaging

(2014) Sankarprasad Bhuniya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Nairovirus Nairobi Sheep Disease Virus/Ganjam Virus Induces the Translocation of Protein Disulphide Isomerase-Like Oxidoreductases from the Endoplasmic Reticulum to the Cell Surface and the Extracellular Space

(2014) Lidia Lasecka et al.   PLoS One

Regulated spatial organization and sensitivity of cytosolic protein oxidation in Caenorhabditis elegans

(2014) Catalina Romero-Aristizabal et al.   Nature Communications

Epidermal Growth Factor Receptor-Containing Exosomes Induce Tumor-Specific Regulatory T Cells

(2013) Shao-hong Huang et al.   CANCER INVESTIGATION

Secretion of ERP57 is important for extracellular matrix accumulation and progression of renal fibrosis, and is an early sign of disease onset

(2013) H. Dihazi et al.   JOURNAL OF CELL SCIENCE

Gemcitabine–Coumarin–Biotin Conjugates: A Target Specific Theranostic Anticancer Prodrug

(2013) Sukhendu Maiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell

(2013) Souvik Modi et al.   Nature Nanotechnology

C. elegans Detects Pathogen-Induced Translational Inhibition to Activate Immune Signaling

(2012) Tiffany L. Dunbar et al.   Cell Host & Microbe

Evaluation of invertebrate infection models for pathogenic corynebacteria

(2012) Lisa Ott et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

Thioredoxin 1-Mediated Post-Translational Modifications: Reduction, Transnitrosylation, Denitrosylation, and Related Proteomics Methodologies

(2011) Changgong Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Hepatocyte-Targeting Single Galactose-Appended Naphthalimide: A Tool for Intracellular Thiol Imaging in Vivo

(2011) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Disulfide Isomerase and Host-Pathogen Interaction

(2011) Beatriz S. Stolf et al.   TheScientificWorldJOURNAL

Imaging proteins inside cells with fluorescent tags

(2011) Georgeta Crivat et al.   TRENDS IN BIOTECHNOLOGY

A synthetic icosahedral DNA-based host–cargo complex for functional in vivo imaging

(2011) Dhiraj Bhatia et al.   Nature Communications

An autonomous DNA nanomachine maps spatiotemporal pH changes in a multicellular living organism

(2011) Sunaina Surana et al.   Nature Communications

Fluorescent Protein-Based Redox Probes

(2010) Andreas J. Meyer et al.   ANTIOXIDANTS & REDOX SIGNALING

Scavenger Receptors Mediate Cellular Uptake of Polyvalent Oligonucleotide-Functionalized Gold Nanoparticles

(2010) Pinal C. Patel et al.   BIOCONJUGATE CHEMISTRY

Knockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis

(2009) Dong Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Icosahedral DNA Nanocapsules by Modular Assembly

(2009) Dhiraj Bhatia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional Nucleic Acid Sensors

(2009) Juewen Liu et al.   CHEMICAL REVIEWS

Modulation of an Active-Site Cysteine pKa Allows PDI to Act as a Catalyst of both Disulfide Bond Formation and Isomerization

(2009) Anna-Riikka Karala et al.   JOURNAL OF MOLECULAR BIOLOGY

The  -Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

(2009) R. Vassar et al.   JOURNAL OF NEUROSCIENCE

A DNA nanomachine that maps spatial and temporal pH changes inside living cells

(2009) Souvik Modi et al.   Nature Nanotechnology

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Real-time imaging of the intracellular glutathione redox potential

(2008) Marcus Gutscher et al.   NATURE METHODS