Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP

Retrospective on Cholesterol Homeostasis: The Central Role of Scap

(2018) Michael S. Brown et al.   Annual Review of Biochemistry

dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene‐induced senescence

(2018) Giulia Santinon et al.   EMBO JOURNAL

Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts

(2018) Chao-Kai Hsu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate

(2018) Terytty Yang Li et al.   Nature Communications

Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK

(2017) Jennifer L. Bays et al.   NATURE CELL BIOLOGY

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells

(2016) Jonathan L. Coloff et al.   Cell Metabolism

Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

(2016) Sirio Dupont   EXPERIMENTAL CELL RESEARCH

The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation

(2016) Yael Aylon et al.   GENES & DEVELOPMENT

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Mapping intracellular mechanics on micropatterned substrates

(2016) Kalpana Mandal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation

(2016) Lorissa J. Smulan et al.   Cell Reports

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

(2015) Fei Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

(2015) E. Enzo et al.   EMBO JOURNAL

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions

(2015) K. Takashima et al.   JOURNAL OF CELL SCIENCE

Scap is required for sterol synthesis and crypt growth in intestinal mucosa

(2015) Matthew R. McFarlane et al.   JOURNAL OF LIPID RESEARCH

Mechanical Forces and Growth in Animal Tissues

(2015) Loïc LeGoff et al.   Cold Spring Harbor Perspectives in Biology

Acetate Dependence of Tumors

(2014) Sarah A. Comerford et al.   CELL

Mechanical Role of Actin Dynamics in the Rheology of the Golgi Complex and in Golgi-Associated Trafficking Events

(2014) David Guet et al.   CURRENT BIOLOGY

Connecting the Cytoskeleton to the Endoplasmic Reticulum and Golgi

(2014) Pinar S. Gurel et al.   CURRENT BIOLOGY

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Assembly of High Molecular Weight Complexes of Lipin on a Supported Lipid Bilayer Observed by Atomic Force Microscopy

(2013) Carl E. Creutz et al.   BIOCHEMISTRY

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

From tissue mechanics to transcription factors

(2013) Paul A. Janmey et al.   DIFFERENTIATION

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

(2012) B. Zhao et al.   GENES & DEVELOPMENT

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

(2011) Amy K. Walker et al.   CELL

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Mechanobiology of scarring

(2011) Rei Ogawa   WOUND REPAIR AND REGENERATION

Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

(2010) Masatoshi Ohgushi et al.   Cell Stem Cell

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Insulin-stimulated Interaction with 14-3-3 Promotes Cytoplasmic Localization of Lipin-1 in Adipocytes

(2009) Miklós Péterfy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sumoylation Regulates Nuclear Localization of Lipin-1α in Neuronal Cells

(2009) Guang-Hui Liu et al.   PLoS One

Sphingomyelin synthases regulate production of diacylglycerol at the Golgi

(2008) Maristella Villani et al.   BIOCHEMICAL JOURNAL

Early Stages of Golgi Vesicle and Tubule Formation Require Diacylglycerol

(2008) Lennart Asp et al.   MOLECULAR BIOLOGY OF THE CELL

Mass spectrometric characterization of cholesterol esters and wax esters in epidermis of fetal, adult and keloidal human skin

(2007) Masahiro Tachi et al.   EXPERIMENTAL DERMATOLOGY