MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia

(2017) P Steullet et al.   MOLECULAR PSYCHIATRY

Inflammation, Stress Response, and Redox Dysregulation Biomarkers: Clinical Outcomes and Pharmacological Implications for Psychosis

(2017) Stefania Schiavone et al.   Frontiers in Psychiatry

Relationship between matrix metalloproteinase-9 and oxidative stress in drug-free male schizophrenia: a case control study

(2016) Sivasankar Devanarayanan et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis

(2016) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Adolescence as a period of vulnerability and intervention in schizophrenia: Insights from the MAM model

(2016) Felipe V. Gomes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis

(2016) Lijing Xin et al.   SCHIZOPHRENIA BULLETIN

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

(2016) P. Steullet et al.   SCHIZOPHRENIA RESEARCH

GABAergic Function as a Limiting Factor for Prefrontal Maturation during Adolescence

(2016) Adriana Caballero et al.   TRENDS IN NEUROSCIENCES

Serum S100B Protein is Specifically Related to White Matter Changes in Schizophrenia

(2016) Berko Milleit et al.   Frontiers in Cellular Neuroscience

Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons

(2015) Hirofumi Morishita et al.   BIOLOGICAL PSYCHIATRY

Progressive Reduction in Cortical Thickness as Psychosis Develops: A Multisite Longitudinal Neuroimaging Study of Youth at Elevated Clinical Risk

(2015) Tyrone D. Cannon et al.   BIOLOGICAL PSYCHIATRY

Common or distinct pathways to psychosis? A systematic review of evidence from prospective studies for developmental risk factors and antecedents of the schizophrenia spectrum disorders and affective psychoses

(2015) Kristin R. Laurens et al.   BMC Psychiatry

Microglia function during brain development: New insights from animal models

(2015) Parizad M. Bilimoria et al.   BRAIN RESEARCH

Glutathione Deficit Affects the Integrity and Function of the Fimbria/Fornix and Anterior Commissure in Mice: Relevance for Schizophrenia

(2015) Alberto Corcoba et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Altered serum glyceraldehyde-derived advanced glycation end product (AGE) and soluble AGE receptor levels indicate carbonyl stress in patients with schizophrenia

(2015) Mayu Takeda et al.   NEUROSCIENCE LETTERS

The Promise of Biological Markers for Treatment Response in First-Episode Psychosis: A Systematic Review

(2015) G. Fond et al.   SCHIZOPHRENIA BULLETIN

Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia

(2015) Kim Q. Do et al.   SCHIZOPHRENIA BULLETIN

Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin

(2014) J Rossier et al.   MOLECULAR PSYCHIATRY

Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients

(2014) A Monin et al.   MOLECULAR PSYCHIATRY

Synapse elimination and learning rules co-regulated by MHC class I H2-Db

(2014) Hanmi Lee et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis

(2014) Emily Pollock et al.   NEUROBIOLOGY OF DISEASE

Towards a Psychosis Risk Blood Diagnostic for Persons Experiencing High-Risk Symptoms: Preliminary Results From the NAPLS Project

(2014) Diana O. Perkins et al.   SCHIZOPHRENIA BULLETIN

Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function

(2014) H. Hu et al.   SCIENCE

Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouse

(2014) Daniel J. Schuster et al.   Frontiers in Neuroanatomy

Matrix metalloproteinase-9 involvement in the structural plasticity of dendritic spines

(2014) Michal Stawarski et al.   Frontiers in Neuroanatomy

Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment

(2014) Olivier Bockstael et al.   Frontiers in Molecular Neuroscience

Inflammatory Cytokines and Neurological and Neurocognitive Alterations in the Course of Schizophrenia

(2013) Anna M. Fineberg et al.   BIOLOGICAL PSYCHIATRY

Meta-Analysis of Oxidative Stress in Schizophrenia

(2013) Joshua Flatow et al.   BIOLOGICAL PSYCHIATRY

Developmental Pattern of Perineuronal Nets in the Human Prefrontal Cortex and Their Deficit in Schizophrenia

(2013) Sarah A. Mauney et al.   BIOLOGICAL PSYCHIATRY

The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas

(2013) Helen Könnecke et al.   Clinical & Developmental Immunology

Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne): implementation of an early intervention programme for psychosis in Switzerland

(2013) Philipp Sebastian Baumann et al.   Early Intervention in Psychiatry

ADAMTS proteoglycanases in the physiological and pathological central nervous system

(2013) Sighild Lemarchant et al.   Journal of Neuroinflammation

Plasma levels of mature brain-derived neurotrophic factor (BDNF) and matrix metalloproteinase-9 (MMP-9) in treatment-resistant schizophrenia treated with clozapine

(2013) Hidenaga Yamamori et al.   NEUROSCIENCE LETTERS

An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-κB Activation for Disease-Inducible Gene Transfer

(2013) Abdelwahed Chtarto et al.   PLoS One

Perineuronal nets protect fast-spiking interneurons against oxidative stress

(2013) J.-H. Cabungcal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Gelatinase Inhibitor Neuroprotective Agents Cross the Blood-Brain Barrier

(2012) Major Gooyit et al.   ACS Chemical Neuroscience

Early-Life Insults Impair Parvalbumin Interneurons via Oxidative Stress: Reversal by N-Acetylcysteine

(2012) Jan-Harry Cabungcal et al.   BIOLOGICAL PSYCHIATRY

Is the Gly82Ser polymorphism in the RAGE gene relevant to schizophrenia and the personality trait psychoticism?

(2012) Petra Suchankova et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2012) S G Fillman et al.   MOLECULAR PSYCHIATRY

Behavioral phenotyping of glutathione-deficient mice: Relevance to schizophrenia and bipolar disorder

(2011) Anita Kulak et al.   BEHAVIOURAL BRAIN RESEARCH

N-Acetylcysteine Normalizes Neurochemical Changes in the Glutathione-Deficient Schizophrenia Mouse Model During Development

(2011) Joao Miguel das Neves Duarte et al.   BIOLOGICAL PSYCHIATRY

S100B alters neuronal survival and dendrite extension via RAGE-mediated NF-κB signaling

(2011) Alejandro Villarreal et al.   JOURNAL OF NEUROCHEMISTRY

Psychosocial stress is associated with in vivo dopamine release in human ventromedial prefrontal cortex: A positron emission tomography study using [18F]fallypride

(2011) Johan Lataster et al.   NEUROIMAGE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

(2011) David A. Lewis et al.   TRENDS IN NEUROSCIENCES

Extracellular Matrix-Glial Abnormalities in the Amygdala and Entorhinal Cortex of Subjects Diagnosed With Schizophrenia

(2010) Harry Pantazopoulos et al.   ARCHIVES OF GENERAL PSYCHIATRY

Redox Dysregulation Affects the Ventral But Not Dorsal Hippocampus: Impairment of Parvalbumin Neurons, Gamma Oscillations, and Related Behaviors

(2010) P. Steullet et al.   JOURNAL OF NEUROSCIENCE

Abnormal neural oscillations and synchrony in schizophrenia

(2010) Peter J. Uhlhaas et al.   NATURE REVIEWS NEUROSCIENCE

Serum levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with different psychiatric disorders

(2010) Enzo Emanuele et al.   NEUROSCIENCE LETTERS

Adolescent Maturation of Cortical Dopamine

(2010) Patricio O’Donnell   NEUROTOXICITY RESEARCH

Prenatal Exposure to Maternal Infection and Executive Dysfunction in Adult Schizophrenia

(2009) Alan S. Brown et al.   AMERICAN JOURNAL OF PSYCHIATRY

MR spectroscopy of the human brain with enhanced signal intensity at ultrashort echo times on a clinical platform at 3T and 7T

(2009) Ralf Mekle et al.   MAGNETIC RESONANCE IN MEDICINE

Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia

(2009) B Rodríguez-Santiago et al.   MOLECULAR PSYCHIATRY

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE

DFT Studies of the Ring-Opening Mechanism of SB-3CT, a Potent Inhibitor of Matrix Metalloproteinase 2

(2009) Peng Tao et al.   ORGANIC LETTERS

Soluble receptor for advanced glycation end products: a new biomarker in diagnosis and prognosis of chronic inflammatory diseases

(2009) H. Maillard-Lefebvre et al.   RHEUMATOLOGY

Functional polymorphism of the matrix metalloproteinase-9 (MMP-9) gene in schizophrenia

(2009) Janusz K. Rybakowski et al.   SCHIZOPHRENIA RESEARCH

Calcium-regulated intramembrane proteolysis of the RAGE receptor

(2008) Arnaud Galichet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A New Pathophysiological Aspect of S100B in Schizophrenia: Potential Regulation of S100B by Its Scavenger Soluble RAGE

(2008) Johann Steiner et al.   BIOLOGICAL PSYCHIATRY

Critical period revisited: impact on vision

(2008) Hirofumi Morishita et al.   CURRENT OPINION IN NEUROBIOLOGY

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

(2008) Angela Raucci et al.   FASEB JOURNAL

Receptor for Advanced Glycation End Products Is Subjected to Protein Ectodomain Shedding by Metalloproteinases

(2008) Ling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia

(2008) M. M. Behrens et al.   JOURNAL OF NEUROSCIENCE

S100B/RAGE-dependent activation of microglia via NF-κB and AP-1

(2008) Roberta Bianchi et al.   NEUROBIOLOGY OF AGING

Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice

(2007) Urs Meyer et al.   BRAIN BEHAVIOR AND IMMUNITY