Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives

Modeling transcriptional factor cross-talk to understand parabolic kinetics, bimodal gene expression and retroactivity in biosensor design

(2019) Hannah Aris et al.   BIOCHEMICAL ENGINEERING JOURNAL

Production of chemicals using dynamic control of metabolic fluxes

(2018) Peng Xu   CURRENT OPINION IN BIOTECHNOLOGY

Optogenetic regulation of engineered cellular metabolism for microbial chemical production

(2018) Evan M. Zhao et al.   NATURE

A Highly Specific Substrate for NanoLUC Luciferase Furimazine Is Toxic in vitro and in vivo

(2018) V. O. Shipunova et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

A Transcription Factor-Based Biosensor for Detection of Itaconic Acid

(2018) Erik K. R. Hanko et al.   ACS Synthetic Biology

Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis

(2018) Yaping Yang et al.   Nature Communications

Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors

(2018) Adam J. Meyer et al.   Nature Chemical Biology

Harnessing a previously unidentified capability of bacterial allosteric transcription factors for sensing diverse small molecules in vitro

(2018) Jiaqian Cao et al.   Science Advances

Synthetic Biology Tools to Engineer Microbial Communities for Biotechnology

(2018) Nicholas S. McCarty et al.   TRENDS IN BIOTECHNOLOGY

Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories

(2017) Abayomi Oluwanbe Johnson et al.   METABOLIC ENGINEERING

Engineering RGB color vision into Escherichia coli

(2017) Jesus Fernandez-Rodriguez et al.   Nature Chemical Biology

Fiber optic biosensor for transdermal glucose based on the glucose binding protein

(2017) Cristina Tiangco et al.   SENSORS AND ACTUATORS B-CHEMICAL

Development of Artificial Riboswitches for Monitoring of Naringenin In Vivo

(2017) Sungho Jang et al.   ACS Synthetic Biology

NanoLuc: A Small Luciferase Is Brightening Up the Field of Bioluminescence

(2016) Christopher G. England et al.   BIOCONJUGATE CHEMISTRY

A Synthetic Hybrid Promoter for Xylose-Regulated Control of Gene Expression in Saccharomyces Yeasts

(2016) Ronald E. Hector et al.   MOLECULAR BIOTECHNOLOGY

Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast

(2016) Mette L Skjoedt et al.   Nature Chemical Biology

Opportunities in the design and application of RNA for gene expression control

(2016) Maureen McKeague et al.   NUCLEIC ACIDS RESEARCH

Luciferase NanoLuc as a reporter for gene expression and protein levels inSaccharomyces cerevisiae

(2016) Anna E. Masser et al.   YEAST

Engineering an NADPH/NADP+ Redox Biosensor in Yeast

(2016) Jie Zhang et al.   ACS Synthetic Biology

Engineering Modular Biosensors to Confer Metabolite-Responsive Regulation of Transcription

(2016) Andrew K. D. Younger et al.   ACS Synthetic Biology

Flux Control at the Malonyl-CoA Node through Hierarchical Dynamic Pathway Regulation in Saccharomyces cerevisiae

(2016) Florian David et al.   ACS Synthetic Biology

Design and engineering of intracellular-metabolite-sensing/regulation gene circuits inSaccharomyces cerevisiae

(2015) Meng Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Engineering metabolism through dynamic control

(2015) Naveen Venayak et al.   CURRENT OPINION IN BIOTECHNOLOGY

Applications and advances of metabolite biosensors for metabolic engineering

(2015) Di Liu et al.   METABOLIC ENGINEERING

The New State of the Art: Cas9 for Gene Activation and Repression

(2015) Marie F. La Russa et al.   MOLECULAR AND CELLULAR BIOLOGY

An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose

(2015) William C DeLoache et al.   Nature Chemical Biology

Development of a Synthetic Malonyl-CoA Sensor in Saccharomyces cerevisiae for Intracellular Metabolite Monitoring and Genetic Screening

(2015) Sijin Li et al.   ACS Synthetic Biology

GPCR-Based Chemical Biosensors for Medium-Chain Fatty Acids

(2015) Kuntal Mukherjee et al.   ACS Synthetic Biology

A general strategy to construct small molecule biosensors in eukaryotes

(2015) Justin Feng et al.   eLife

Transcription factor-based biosensors enlightened by the analyte

(2015) Raul Fernandez-López et al.   Frontiers in Microbiology

Bacterial XylRs and synthetic promoters function as genetically encoded xylose biosensors inSaccharomyces cerevisiae

(2014) Wei Suong Teo et al.   Biotechnology Journal

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

(2014) Alexander A. Green et al.   CELL

Programmable bacteria detect and record an environmental signal in the mammalian gut

(2014) Jonathan W. Kotula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving fatty acids production by engineering dynamic pathway regulation and metabolic control

(2014) P. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Transfer of Prokaryotic Sensors and Circuits to Mammalian Cells

(2014) Brynne C. Stanton et al.   ACS Synthetic Biology

Design and Kinetic Analysis of a Hybrid Promoter–Regulator System for Malonyl-CoA Sensing in Escherichia coli

(2013) Peng Xu et al.   ACS Chemical Biology

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Bacterial FadR and synthetic promoters function as modular fatty acid sensor- regulators inSaccharomyces cerevisiae

(2013) Wei Suong Teo et al.   ENGINEERING IN LIFE SCIENCES

Modular optimization of multi-gene pathways for fatty acids production in E. coli

(2013) Peng Xu et al.   Nature Communications

Synthetic Gene Circuit-Mediated Monitoring of Endogenous Metabolites: Identification of GAL11 as a Novel Multicopy Enhancer of S-Adenosylmethionine Level in Yeast

(2013) Taichi Umeyama et al.   ACS Synthetic Biology

Genetic Sensor for Strong Methylating Compounds

(2013) Felix Moser et al.   ACS Synthetic Biology

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

(2012) Mary P. Hall et al.   ACS Chemical Biology

A Genetically Encoded Metabolite Sensor for Malonyl-CoA

(2012) Jessica M. Ellis et al.   CHEMISTRY & BIOLOGY

Engineering plant metabolism into microbes: from systems biology to synthetic biology

(2012) Peng Xu et al.   CURRENT OPINION IN BIOTECHNOLOGY

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids

(2012) Fuzhong Zhang et al.   NATURE BIOTECHNOLOGY

ePathBrick: A Synthetic Biology Platform for Engineering Metabolic Pathways in E. coli

(2012) Peng Xu et al.   ACS Synthetic Biology

Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways

(2011) Joshua K. Michener et al.   METABOLIC ENGINEERING

Engineering Biological Systems with Synthetic RNA Molecules

(2011) Joe C. Liang et al.   MOLECULAR CELL

Engineering Yarrowia lipolytica to express secretory invertase with strong FBA1IN promoter

(2011) Seung-Pyo Hong et al.   YEAST

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Tracking, tuning, and terminating microbial physiology using synthetic riboregulators

(2010) J. M. Callura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Structural basis for leucine-rich nuclear export signal recognition by CRM1

(2009) Xiuhua Dong et al.   NATURE