Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast

CRISPR/Cas9 advances engineering of microbial cell factories

(2016) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

Genetically encoded sensors enable real-time observation of metabolite production

(2016) Jameson K. Rogers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Synthetic Erectile Optogenetic Stimulator Enabling Blue-Light-Inducible Penile Erection

(2015) Taeuk Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and engineering of intracellular-metabolite-sensing/regulation gene circuits inSaccharomyces cerevisiae

(2015) Meng Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Amplification of small molecule-inducible gene expression via tuning of intracellular receptor densities

(2015) Baojun Wang et al.   NUCLEIC ACIDS RESEARCH

Bacterial XylRs and synthetic promoters function as genetically encoded xylose biosensors inSaccharomyces cerevisiae

(2014) Wei Suong Teo et al.   Biotechnology Journal

Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance

(2014) Kanchana R. Kildegaard et al.   METABOLIC ENGINEERING

Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae

(2014) R. Scott McIsaac et al.   NUCLEIC ACIDS RESEARCH

Evolution-guided optimization of biosynthetic pathways

(2014) Srivatsan Raman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomically encoded analog memory with precise in vivo DNA writing in living cell populations

(2014) F. Farzadfard et al.   SCIENCE

Rational Design of a Fusion Protein to Exhibit Disulfide-Mediated Logic Gate Behavior

(2014) Jay H. Choi et al.   ACS Synthetic Biology

Systematic Transfer of Prokaryotic Sensors and Circuits to Mammalian Cells

(2014) Brynne C. Stanton et al.   ACS Synthetic Biology

“Malonate Uptake and Metabolism in Saccharomyces cerevisiae”

(2013) Wei Ning Chen et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

EasyClone: method for iterative chromosomal integration of multiple genes inSaccharomyces cerevisiae

(2013) Niels B. Jensen et al.   FEMS YEAST RESEARCH

Novel biosensors based on flavonoid-responsive transcriptional regulators introduced into Escherichia coli

(2013) Solvej Siedler et al.   METABOLIC ENGINEERING

Genome-scale engineering for systems and synthetic biology

(2013) K. M. Esvelt et al.   Molecular Systems Biology

Genomic mining of prokaryotic repressors for orthogonal logic gates

(2013) Brynne C Stanton et al.   Nature Chemical Biology

Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay

(2013) Michael E. Lee et al.   NUCLEIC ACIDS RESEARCH

Synthetic mammalian trigger-controlled bipartite transcription factors

(2013) Marc Folcher et al.   NUCLEIC ACIDS RESEARCH

Dynamically Reshaping Signaling Networks to Program Cell Fate via Genetic Controllers

(2013) K. E. Galloway et al.   SCIENCE

Activating Transcription in Bacteria

(2012) David J. Lee et al.   Annual Review of Microbiology

A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions

(2012) Ahmad S. Khalil et al.   CELL

High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch

(2012) Joshua K. Michener et al.   METABOLIC ENGINEERING

Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform

(2012) Michael Dalgaard Mikkelsen et al.   METABOLIC ENGINEERING

Metabolic engineering of muconic acid production in Saccharomyces cerevisiae

(2012) Kathleen A. Curran et al.   METABOLIC ENGINEERING

De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae

(2012) Frank Koopman et al.   Microbial Cell Factories

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Optimization of ordered plasmid assembly by gap repair in Saccharomyces cerevisiae

(2012) Nadine Eckert-Boulet et al.   YEAST

The LysR-type PcaQ protein regulates expression of a protocatechuate-inducible ABC-type transport system in Sinorhizobium meliloti

(2011) A. M. MacLean et al.   MICROBIOLOGY-SGM

Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae

(2009) Michael Naesby et al.   Microbial Cell Factories

Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins

(2008) S. E. Maddocks et al.   MICROBIOLOGY-SGM