High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components
Authors
Keywords
FGF21, <em class="EmphasisTypeItalic ">Bacillus subtilis</em>, Heterologous protein expression, Mini-cistron, Chaperone, Signal peptide
Journal
Microbial Cell Factories
Volume 18, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-01-28
DOI
10.1186/s12934-019-1066-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Enhanced extracellular pullulanase production in Bacillus subtilis using protease-deficient strains and optimal feeding
- (2018) Kang Zhang et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- High-Efficiency Secretion of β-Mannanase in Bacillus subtilis through Protein Synthesis and Secretion Optimization
- (2017) Yafeng Song et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Recombinant production of the antibody fragment D1.3 scFv with different Bacillus strains
- (2017) Antonia Lakowitz et al. Microbial Cell Factories
- High-level extracellular protein production in Bacillus subtilis using an optimized dual-promoter expression system
- (2017) Kang Zhang et al. Microbial Cell Factories
- Multimer recognition and secretion by the non-classical secretion pathway in Bacillus subtilis
- (2017) Liuqun Zhao et al. Scientific Reports
- Characterization of transcription factor response kinetics in parallel
- (2016) Betul Bilgin et al. BMC BIOTECHNOLOGY
- High-level intra- and extra-cellular production of d-psicose 3-epimerase via a modified xylose-inducible expression system in Bacillus subtilis
- (2016) Jingqi Chen et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis
- (2016) Jingqi Chen et al. Microbial Cell Factories
- Cultivation strategies to enhance productivity of Pichia pastoris: A review
- (2015) V. Looser et al. BIOTECHNOLOGY ADVANCES
- Improving Protein Production on the Level of Regulation of both Expression and Secretion Pathways in Bacillus subtilis
- (2015) Yafeng Song et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production
- (2014) Mudassar Ahmad et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Optimisation of the mRNA secondary structure to improve the expression of interleukin-24 (IL-24) in Escherichia coli
- (2014) Chaogang Bai et al. BIOTECHNOLOGY LETTERS
- Twin-Arginine Signal Peptide of Bacillus subtilis YwbN Can Direct Tat-Dependent Secretion of Methyl Parathion Hydrolase
- (2014) Ruihua Liu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Current development in genetic engineering strategies of Bacillus species
- (2014) Huina Dong et al. Microbial Cell Factories
- Inventing new medicines: The FGF21 story
- (2014) Alexei Kharitonenkov et al. Molecular Metabolism
- An updated metabolic view of the Bacillus subtilis 168 genome
- (2013) E. Belda et al. MICROBIOLOGY-SGM
- Precise and reliable gene expression via standard transcription and translation initiation elements
- (2013) Vivek K Mutalik et al. NATURE METHODS
- Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319
- (2013) Alexei Kharitonenkov et al. PLoS One
- Construction of an artificial secYEG operon allowing high level secretion of α-amylase
- (2013) Kelly C.L. Mulder et al. PROTEIN EXPRESSION AND PURIFICATION
- Production of α-Cyclodextrin Glycosyltransferase in Bacillus megaterium MS941 by Systematic Codon Usage Optimization
- (2012) Jingwen Zhou et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Large-scale expression, purification, and glucose uptake activity of recombinant human FGF21 in Escherichia coli
- (2011) Minjing Zhang et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21)in Vivo
- (2011) ffolliott M. Fisher et al. ENDOCRINOLOGY
- Bioprocess engineering aspects of heterologous protein production in Pichia pastoris: A review
- (2010) Gabriel Potvin et al. BIOCHEMICAL ENGINEERING JOURNAL
- High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli
- (2010) Huiyan Wang et al. BMC BIOTECHNOLOGY
- FGF21 reloaded: challenges of a rapidly growing field
- (2010) Alexei Kharitonenkov et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Expression system for recombinant human growth hormone production fromBacillus subtilis
- (2009) Tunçer H. Özdamar et al. BIOTECHNOLOGY PROGRESS
- Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity
- (2009) Eric D. Berglund et al. ENDOCRINOLOGY
- Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes
- (2009) Katsumi Iizuka et al. FEBS LETTERS
- Towards the development of Bacillus subtilis as a cell factory for membrane proteins and protein complexes
- (2008) Jessica C Zweers et al. Microbial Cell Factories
- A novel bicistronic vector for overexpressing Mycobacterium tuberculosis proteins in Escherichia coli
- (2008) Yin Guo et al. PROTEIN EXPRESSION AND PURIFICATION
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started