Non-Anticoagulant Heparin Prodrug Loaded Biodegradable and Injectable Thermoresponsive Hydrogels for Enhanced Anti-Metastasis Therapy

Bioinspired, Manganese-Chelated Alginate–Polydopamine Nanomaterials for Efficient in Vivo T1-Weighted Magnetic Resonance Imaging

(2018) Kefyalew Dagnew Addisu et al.   ACS Applied Materials & Interfaces

Biodegradable copolypeptide hydrogel prodrug accelerates dermal wound regeneration by enhanced angiogenesis and epithelialization

(2018) Anqi Chen et al.   RSC Advances

Injectable hydrogels for sustained release of therapeutic agents

(2017) Thavasyappan Thambi et al.   JOURNAL OF CONTROLLED RELEASE

Structural and Rheological Properties of Temperature-Responsive Amphiphilic Triblock Copolymers in Aqueous Media

(2017) Josefine Eilsø Nielsen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Synthesis and characterization of redox-sensitive heparin-β-sitosterol micelles: Their application as carriers for the pharmaceutical agent, doxorubicin, and investigation of their antimetastatic activities in vitro

(2017) Tilahun Ayane Debele et al.   Materials Science & Engineering C-Materials for Biological Applications

Temperature and pH-sensitive injectable hydrogels based on poly(sulfamethazine carbonate urethane) for sustained delivery of cationic proteins

(2017) V.H. Giang Phan et al.   POLYMER

Antitumor and Antimetastasis Activities of Heparin-based Micelle Served As Both Carrier and Drug

(2016) Ling Mei et al.   ACS Applied Materials & Interfaces

Injectable and Thermosensitive Hydrogel Containing Liraglutide as a Long-Acting Antidiabetic System

(2016) Yipei Chen et al.   ACS Applied Materials & Interfaces

Comparative Study of Heparin-Poloxamer Hydrogel Modified bFGF and aFGF for in Vivo Wound Healing Efficiency

(2016) Jiang Wu et al.   ACS Applied Materials & Interfaces

Injectable hydrogel-based drug delivery systems for local cancer therapy

(2016) Mohammad Norouzi et al.   DRUG DISCOVERY TODAY

Anti-metastatic activity of fangchinoline in human gastric cancer AGS cells

(2016) Zhengrong Chen et al.   Oncology Letters

Biomedical Applications of Biodegradable Polyesters

(2016) Iman Manavitehrani et al.   Polymers

Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FRα

(2016) Yuhan Yang et al.   Scientific Reports

Localized Co-delivery of Doxorubicin, Cisplatin, and Methotrexate by Thermosensitive Hydrogels for Enhanced Osteosarcoma Treatment

(2015) Hecheng Ma et al.   ACS Applied Materials & Interfaces

Cytocompatible in situ forming chitosan/hyaluronan hydrogels via a metal-free click chemistry for soft tissue engineering

(2015) Ming Fan et al.   Acta Biomaterialia

Effect of Selective Heparin Desulfation on Preservation of Bone Morphogenetic Protein-2 Bioactivity after Thermal Stress

(2015) Song P. Seto et al.   BIOCONJUGATE CHEMISTRY

Sustained intra-articular release of celecoxib from in situ forming gels made of acetyl-capped PCLA-PEG-PCLA triblock copolymers in horses

(2015) Audrey Petit et al.   BIOMATERIALS

Development of individualized anti-metastasis strategies by engineering nanomedicines

(2015) Qianjun He et al.   CHEMICAL SOCIETY REVIEWS

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

(2015) Uwe Freudenberg et al.   JOURNAL OF CONTROLLED RELEASE

Stimulus-responsive hydrogels: Theory, modern advances, and applications

(2015) Michael C. Koetting et al.   MATERIALS SCIENCE & ENGINEERING R-REPORTS

Nanostructure controlled sustained delivery of human growth hormone using injectable, biodegradable, pH/temperature responsive nanobiohybrid hydrogel

(2015) Narendra K. Singh et al.   Nanoscale

Heparin-based temperature-sensitive injectable hydrogels for protein delivery

(2015) Hye Jin Sim et al.   Journal of Materials Chemistry B

Release behavior and intra-articular biocompatibility of celecoxib-loaded acetyl-capped PCLA-PEG-PCLA thermogels

(2014) Audrey Petit et al.   BIOMATERIALS

Anti-metastasis efficacy and safety of non-anticoagulant heparin derivative versus low molecular weight heparin in surgical pancreatic cancer models

(2014) REEM ALYAHYA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Mechanisms of lymphatic metastasis

(2014) Sinem Karaman et al.   JOURNAL OF CLINICAL INVESTIGATION

Smart hydrogels as functional biomimetic systems

(2014) Han L. Lim et al.   Biomaterials Science

In situ forming acyl-capped PCLA–PEG–PCLA triblock copolymer based hydrogels

(2013) Maria J. Sandker et al.   BIOMATERIALS

Injectable and Thermoresponsive Self-Assembled Nanocomposite Hydrogel for Long-Term Anticancer Drug Delivery

(2013) Ying-Yu Chen et al.   LANGMUIR

Modulating rheological and degradation properties of temperature-responsive gelling systems composed of blends of PCLA–PEG–PCLA triblock copolymers and their fully hexanoyl-capped derivatives

(2012) Audrey Petit et al.   Acta Biomaterialia

Thermosensitive sol–gel reversible hydrogels

(2012) Byeongmoon Jeong et al.   ADVANCED DRUG DELIVERY REVIEWS

Why does cancer therapy lack effective anti-metastasis drugs?

(2012) Georg F. Weber   CANCER LETTERS

Dually cationic and anionic pH/temperature-sensitive injectable hydrogels and potential application as a protein carrier

(2012) Cong Truc Huynh et al.   CHEMICAL COMMUNICATIONS

Temperature-responsive compounds as in situ gelling biomedical materials

(2012) Hyo Jung Moon et al.   CHEMICAL SOCIETY REVIEWS

Inhibitory effect of non-anticoagulant heparin (S-NACH) on pancreatic cancer cell adhesion and metastasis in human umbilical cord vessel segment and in mouse model

(2012) Thangirala Sudha et al.   CLINICAL & EXPERIMENTAL METASTASIS

Biodegradable and thermoreversible PCLA–PEG–PCLA hydrogel as a barrier for prevention of post-operative adhesion

(2011) Zheng Zhang et al.   BIOMATERIALS

Synergistic effects of Akt1 shRNA and paclitaxel-incorporated conjugated linoleic acid-coupled poloxamer thermosensitive hydrogel on breast cancer

(2011) Ding-Ding Guo et al.   BIOMATERIALS

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Initial steps of metastasis: Cell invasion and endothelial transmigration

(2011) Franziska van Zijl et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Study on anti-metastasis of heparin derivatives as ligand antagonist of p-selectin

(2010) Y. Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-κB activity and downregulation of PI3K/AKT/small GTPase signals

(2010) Hsieh-Hsun Ho et al.   FOOD AND CHEMICAL TOXICOLOGY

Encapsulation and Controlled Release of Heparin from Electrospun Poly(L-Lactide-co-ε-Caprolactone) Nanofibers

(2010) Yan Su et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Anticoagulation Management

(2010) Blaze Cook   SEMINARS IN INTERVENTIONAL RADIOLOGY

Hydrogels in Regenerative Medicine

(2009) Brandon V. Slaughter et al.   ADVANCED MATERIALS

A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy

(2009) Hang T. Ta et al.   BIOMATERIALS

Metastatic Cancer Cell

(2008) Marina Bacac et al.   Annual Review of Pathology-Mechanisms of Disease

In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery

(2008) Chaoliang He et al.   JOURNAL OF CONTROLLED RELEASE

Temperature-Sensitive Poly(caprolactone-co-trimethylene carbonate)−Poly(ethylene glycol)−Poly(caprolactone-co-trimethylene carbonate) as in Situ Gel-Forming Biomaterial

(2008) So Hyun Park et al.   MACROMOLECULES

Controlled release of heparin from blended polyurethane and silk fibroin film

(2008) Xiu-Ying Liu et al.   MATERIALS LETTERS