Article
Polymer Science
Yanyao Zhang, Yusheng Tang, Junliang Zhang, Simon Harrisson
Summary: The fluorescence properties of the copolymer can be adjusted by rationally designing the copolymer structure. The asymmetric diblock copolymer shows a gradual increase in fluorescent intensity as the environmental pH decreases, in contrast to the limited and stepwise change of its symmetric block counterpart.
Article
Biochemistry & Molecular Biology
Jianyang Zhao, Yi-Yang Peng, Jinquan Wang, Diana Diaz-Dussan, Wendy Tian, Wei Duan, Lingxue Kong, Xiaojuan Hao, Ravin Narain
Summary: In this study, a temperature-responsive aldehyde hydrogel with dual physical-cross-linked networks and injectable and self-healing properties was developed. The gelation temperature and mechanical properties of the hydrogel could be tuned by adjusting the content of aldehyde groups in the triblock copolymer. The hydrogel demonstrated excellent biocompatibility, injectability, and self-healing properties, making it a promising candidate for tissue engineering applications.
Article
Polymer Science
Albert Prause, Michelle Hechenbichler, Robert F. Schmidt, Miriam Simon, Sylvain Prevost, Leide P. Cavalcanti, Yeshayahu Talmon, Andre Laschewsky, Michael Gradzielski
Summary: Temperature control of rheological properties of aqueous solutions can be achieved by the addition of temperature-responsive amphiphilic polymers. In this study, three sets of acrylamide-based block copolymers with different architectures were explored, and their viscosities showed a substantial increase with increasing temperature. The changes in rheological properties were correlated with the mesoscopic organization of the systems.
Article
Polymer Science
Anton A. A. Smith, Caitlin L. Maikawa, Hector Lopez Hernandez, Eric A. Appel
Summary: The properties of thermogelling tri-block copolymers can be tuned by altering the random terpolymer compositions, allowing for controlled modulation of thermogel properties. By controlling the lower critical solution temperature (LCST) of the pendant blocks, the heterogeneity of the pendant terpolymer blocks can be reflected in the concentration dependence of their critical solution behavior.
Article
Chemistry, Multidisciplinary
Maria Tomara, Dimitrios Selianitis, Stergios Pispas
Summary: This study reports the synthesis and self-assembly of a new series of dual-responsive polymers in aqueous solutions. These polymers respond to changes in pH, temperature, and ionic strength, can encapsulate hydrophobic drugs, and show potential applications as nanocarriers for drug delivery.
Review
Polymer Science
Guangran Shao, Yuan Liu, Rong Cao, Guang Han, Bing Yuan, Wangqing Zhang
Summary: Thermo-responsive block copolymers have attracted a lot of attention due to their mature synthesis technology, well-defined structure, controllable molecular weight, and easy implementation of their nano-assemblies in water through temperature regulation. Previous reviews have mainly focused on their biomedical applications, but these polymers also show promising potential in temperature-regulated adsorption and/or separation, nanoreactors for green organic synthesis, etc. This review summarizes the recent progress in thermo-responsive assembly in water and highlights the applications of five different thermo-responsive block copolymers beyond the biomedical field.
Article
Polymer Science
Qianyu Lin, Chen Chuan Lim, Cally Owh, Joey Hui Min Wong, Valerie Ow, Belynn Sim, Yi Jian Boo, Michelle P. Y. Yew, Yi Hao Leow, Liangfeng Guo, Jason Y. C. Lim, Xian Jun Loh
Summary: Thermogels are a type of supramolecular hydrogels that undergo reversible sol-gel phase transitions and their unique properties depend on the hydrophilic-hydrophobic balance of the constituent polymers. Most thermogelling polymers use polyethylene glycol (PEG) as the hydrophilic segment, but this study introduces PEG-free amphiphilic polymers comprising only polyethylenimine (PEI) and polypropylene glycol (PPG) as the hydrophilic and hydrophobic segments, respectively. These polymers can self-assemble into micelles and supramolecular gel matrices. By modifying the PEI-PPG copolymers with benzyl groups, the resulting thermogel properties can be conveniently modulated. The hydrophobic-hydrophilic balance of the copolymers can also be adjusted to tune the critical gelation concentrations, gelation temperatures, and gel viscoelastic properties. In addition, the PEI segment exhibits pH-responsiveness, allowing for further alteration of thermogel viscoelasticity through pH adjustment. The convenience of postsynthetic functionalization, new material properties, and dual stimuli-responsiveness of these polycationic PEI-PPG thermogels can potentially offer a vast material design space for many unique applications.
Article
Polymer Science
Deniz Coban, Olga Gridina, Matthias Karg, Andre H. Groeschel
Summary: This study describes design rules for controlling the morphology of multicompartment micelles (MCMs) in water and proposes a method to predict the final MCM shape based on the molar ratio of PEO to PMA.
Article
Nanoscience & Nanotechnology
Chunchun Liang, Mengwei Li, Yulan Chen
Summary: This study reports a series of amphiphilic diazapyrenes that exhibit switchable fluorescence under mechanical force or water vapor stimulation. Through comprehensive studies of their photophysical properties, a stimuli-induced excimer-based sensing mechanism was revealed, and the relationship between molecular structures and optical responsive properties was illustrated. The unique fluorescent, stimuli-responsive behaviors of these compounds in the solid state were used to create sensory films for sensing mechanical force and water vapor, showing potential applications in biocompatible force sensors, data storage, and humidity sensors.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Polymer Science
Lauren E. E. Ball, Gabriela Garbonova, Rueben Pfukwa, Bert Klumperman
Summary: Responsive triblock copolymers were synthesized and studied for their potential use in drug delivery systems in biomedical research.
Article
Chemistry, Multidisciplinary
Joanna M. White, Ally Garza, James J. Griebler, Frank S. Bates, Michelle A. Calabrese
Summary: Commercially available and nontoxic poloxamer 407 (P407), a triblock polymer, undergoes a solution-to-gel transition with increasing temperature and is a potential candidate for injectable therapeutics. Addition of highly soluble reverse poloxamers (RPs) dramatically affects the gelation temperature, modulus, and morphology of P407-based hydrogels. This tunability allows for the design of thermoresponsive materials with specific properties.
Article
Polymer Science
Akihide Sugawara, Taka-Aki Asoh, Yoshinori Takashima, Akira Harada, Hiroshi Uyama
Summary: A mechano-responsive hydrogel was developed using the dissociation of a host-guest complex to induce phase transition of a thermoresponsive polymer, demonstrating a decrease in transmittance when mechanical stress was applied. This strategy provides a new approach for applications requiring controlled functions through applied stress.
Article
Chemistry, Physical
Margarita A. Dyakonova, Yanan Li, Ioanna N. Besiri, Zhenyu Di, Isabelle Grillo, Constantinos Tsitsilianis, Christine M. Papadakis
Summary: By investigating a triblock copolymer in a mixture of water and acetone, it is found that the addition of acetone leads to a transition in the rheological properties of the polymer solution from a solid to a liquid state, as well as significant changes in the micellar structure. These changes are attributed to the reduction of dielectric constant by acetone, enhancing the flexibility of the middle blocks and their backfolding tendency, as well as the decrease in solvent selectivity inducing significant exchange rate enhancement of the core-forming PMMA blocks.
COLLOID AND POLYMER SCIENCE
(2021)
Article
Polymer Science
Pei Huang, Meiwei Qi, Chuanshuang Chen, Fugui Xu, Shanlong Li, Qingsong Xu, Hui Pan, Yuling Wang, Chunyang Yu, Shaodong Zhang, Yongfeng Zhou
Summary: The asymmetric distribution of lipids on the inner and outer membranes of a cell is crucial for physiological and immunological activities. Synthetic asymmetric vesicles are prepared using amphiphilic block copolymers, or self-assembled by two hydrophilic segments. Effective fluorescence titration methods can be developed to determine the uneven distribution of segments in the vesicles. This work demonstrates the potential of sequence-controlled polymers for creating challenging self-assembled structures with important functions and properties.
Article
Multidisciplinary Sciences
Farzaneh Ghazizadeh Ahsaie, Gholamreza Pazuki
Summary: The study utilized polymer-salt aqueous two-phase systems (ATPSs) for the separation of 6-aminopenicillanic acid (6-APA) and phenyl acetic acid (PAA), with Na2SO4 selected as the most appropriate salt and 10R5-Na2SO4 ATPS chosen as the optimal separation system. Molecular interactions between these two molecules were investigated, and the results showed a selectivity of approximately 53 with smaller selectivity observed in a mixture system of 6-APA and PAA.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Physical
Erfan Dashtimoghadam, Hamed Salimi-Kenari, Rasool Nasseri, Kenneth D. Knudsen, Hamid Mirzadeh, Bo Nystrom
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2020)
Article
Energy & Fuels
Kenneth D. Knudsen, Sebastien Simon, Thomas Geue, Joshaniel F. K. Cooper, Johan Sjoblom
Article
Chemistry, Multidisciplinary
Jiri Trousil, Oto Pavlis, Pavla Kubickova, Misa Skoric, Vera Maresova, Ewa Pavlova, Kenneth D. Knudsen, You-Shan Dai, Matthew Zimmerman, Veronique Dartois, Jia-You Fang, Martin Hruby
JOURNAL OF CONTROLLED RELEASE
(2020)
Article
Chemistry, Multidisciplinary
Synne Myhre, Matthias Amann, Lutz Willner, Kenneth D. Knudsen, Reidar Lund
Article
Chemistry, Physical
Kristoffer W. Bo Hunvik, Patrick Loch, Leide P. Cavalcanti, Konstanse Kvalem Seljelid, Paul Monceyron Roren, Svemir Rudic, Dirk Wallacher, Alexsandro Kirch, Kenneth Dahl Knudsen, Caetano Rodrigues Miranda, Josef Breu, Heloisa N. Bordallo, Jon Otto Possum
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Article
Chemistry, Multidisciplinary
Paulo H. Michels-Brito, Antonio Malfatti-Gasperini, Lina Mayr, Ximena Puentes-Martinez, Romulo P. Tenorio, Daniel R. Wagner, Kenneth D. Knudsen, Koiti Araki, Rafael G. Oliveira, Josef Breu, Leide P. Cavalcanti, Jon Otto Fossum
Summary: In this study, unmodified clay nanosheets were found to be able to localize at air-deionized-water interfaces, offering new possibilities for research on novel clay interface materials. By combining different experimental methods, the dynamic equilibrium of clay nanosheet organization at the interface was revealed.
Article
Polymer Science
Nico Koenig, Lutz Willner, Goran Carlstrom, Thomas Zinn, Kenneth D. Knudsen, Frode Rise, Daniel Topgaard, Reidar Lund
Article
Nanoscience & Nanotechnology
Anastasiia Karabanova, Kenneth Dahl Knudsen, Perizat Berdiyeva, Leide P. Cavalcanti, Yun Liu, Michel van der Pal, Stefano Deledda, Didier Blanchard
Summary: This study utilized SANS, X-ray diffraction, and sorption measurements to investigate the structural evolution of a SrCl2-expanded natural graphite composite during ammonia absorption and desorption. Structural changes were found to affect absorption rate, while having no significant impact on desorption rate. Furthermore, the formation of nanopores significantly enhanced absorption kinetics.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Kristoffer W. Bo Hunvik, Patrick Loch, Dirk Wallacher, Alexsandro Kirch, Leide P. Cavalcanti, Martin Riess, Matthias Daab, Vegard Josvanger, Sven Graetz, Fabiano Yokaichiya, Kenneth Dahl Knudsen, Caetano Rodrigues Miranda, Josef Breu, Jon Otto Fossum
Summary: The research reveals that as the interlayer surface charge in clay minerals decreases, the adsorption capacity for CO2 increases and the pressure threshold for adsorption and swelling in response to CO2 decreases. Different layer charges in clay minerals exhibit varying CO2 adsorption capacities and release mechanisms.
Article
Chemistry, Physical
Kristoffer W. Bo Hunvik, Rodrigo Jose da Silva Lima, Alexsandro Kirch, Patrick Loch, Paul Monceyron Roren, Martin Hoffmann Petersen, Svemir Rudic, Victoria Garcia Sakai, Kenneth Dahl Knudsen, Caetano Rodrigues Miranda Materiais Instituto, Josef Breu, Jon Otto Fossum, Heloisa N. Bordallo
Summary: Developing technologies for carbon sequestration and storage is crucial, and clay minerals show promise in this regard. This study investigates the intercalation mechanisms of CO2 in dehydrated and hydrated synthetic hectorite clay. The results suggest that intercalated water molecules create physical space for CO2 intercalation, and the presence of interlayer confinement affects the hydration of Na+ ions and may facilitate the adsorption of CO2 in the form of carbonates.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Agriculture, Multidisciplinary
Julia Jianwei Tan, Natalie Gjerde, Alessandra Del Giudice, Kenneth D. Knudsen, Luciano Galantini, Guanqun Du, Karin Schillen, Sverre Arne Sande, Bo Nystrom
Summary: This study investigates the interactions between cationic hydroxyethyl cellulose (catHEC) and sodium deoxycholate (NaDC) or sodium cholate (NaC). It is found that there are strong interactions between catHEC and NaDC, while the interactions with NaC are weak. This difference may be due to the ability of NaDC to form more connections and entanglements.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Polymer Science
Pierre Carmona, Anca M. Tasici, Sverre A. Sande, Kenneth D. Knudsen, Bo Nystrom
Summary: The rheological changes during the chemical gelation process of chitosan with the low-toxicity agent glyceraldehyde were studied. Factors such as crosslinker concentration, temperature, and pH were found to influence the gelation process. Small angle neutron scattering results showed structural changes in chitosan solutions under different conditions.
Article
Nanoscience & Nanotechnology
Darya Zeini, Joel C. Glover, Kenneth D. Knudsen, Bo Nystrom
Summary: The study found that dextran conjugates with lysine and TRITC of different molecular weights exhibited variations in molecular volumes and mobility within axons. Surprisingly, lower molecular weight conjugated dextrans showed higher efficiency in translocation despite having larger molecular volumes compared to higher molecular weight dextrans.
ACS APPLIED BIO MATERIALS
(2021)
Article
Chemistry, Physical
Patrick Loch, Kristoffer William Bo Hunvik, Florian Puchtler, Sebastian Weiss, Konstanse Kvalem Seljelid, Paul Monceyron Roren, Svemir Rudic, Steinar Raaen, Kenneth Dahl Knudsen, Heloisa N. Bordallo, Jon Otto Fossum, Josef Breu
APPLIED CLAY SCIENCE
(2020)
Article
Chemistry, Physical
L. Michels, C. L. S. da Fonseca, Y. Meheust, M. A. S. Altoe, E. C. dos Santos, G. Grassi, R. Droppa, K. D. Knudsen, L. P. Cavalcanti, K. W. B. Hunvik, J. O. Fossum, G. J. da Silva, H. N. Bordallo
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)