Emerging techniques for ultrasensitive protein analysis

Amplified binding-induced homogeneous assay through catalytic cycling of analyte for ultrasensitive protein detection

(2016) Junbo Chen et al.   CHEMICAL COMMUNICATIONS

DLISA: A DNAzyme-Based ELISA for Protein Enzyme-Free Immunoassay of Multiple Analytes

(2015) Rong Hu et al.   ANALYTICAL CHEMISTRY

Alcohol Dehydrogenase-Catalyzed Gold Nanoparticle Seed-Mediated Growth Allows Reliable Detection of Disease Biomarkers with the Naked Eye

(2015) Mao-Pan Peng et al.   ANALYTICAL CHEMISTRY

Classification of Large Cellular Populations and Discovery of Rare Cells Using Single Cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

(2015) Ta-Hsuan Ong et al.   ANALYTICAL CHEMISTRY

Label-Free Nanopore Proximity Bioassay for Platelet-Derived Growth Factor Detection

(2015) Ling Zhang et al.   ANALYTICAL CHEMISTRY

Nearly 1000 Protein Identifications from 50 ng of Xenopus laevis Zygote Homogenate Using Online Sample Preparation on a Strong Cation Exchange Monolith Based Microreactor Coupled with Capillary Zone Electrophoresis

(2015) Zhenbin Zhang et al.   ANALYTICAL CHEMISTRY

Universal Strategy To Engineer Catalytic DNA Hairpin Assemblies for Protein Analysis

(2015) Yanan Tang et al.   ANALYTICAL CHEMISTRY

Target-regulated proximity hybridization with three-way DNA junction for in situ enhanced electronic detection of marine biotoxin based on isothermal cycling signal amplification strategy

(2015) Bingqian Liu et al.   BIOSENSORS & BIOELECTRONICS

Silver nanoprism etching-based plasmonic ELISA for the high sensitive detection of prostate-specific antigen

(2015) Jiajie Liang et al.   BIOSENSORS & BIOELECTRONICS

A microfluidic platform with digital readout and ultra-low detection limit for quantitative point-of-care diagnostics

(2015) Ying Li et al.   LAB ON A CHIP

Single-Digit Pathogen and Attomolar Detection with the Naked Eye Using Liposome-Amplified Plasmonic Immunoassay

(2015) Minh-Phuong Ngoc Bui et al.   NANO LETTERS

Simple electrochemical sensing of attomolar proteins using fabricated complexes with enhanced surface binding avidity

(2015) Chao Li et al.   Chemical Science

High-throughput imaging assay of multiple proteins via target-induced DNA assembly and cleavage

(2015) Chen Zong et al.   Chemical Science

Ultra-sensitive protein detection via Single Molecule Arrays towards early stage cancer monitoring

(2015) Stephanie M. Schubert et al.   Scientific Reports

A Plasmonic Nanosensor for Immunoassay via Enzyme-Triggered Click Chemistry

(2014) Yunlei Xianyu et al.   ACS Nano

Strip biosensor for amplified detection of nerve growth factor-beta based on a molecular translator and catalytic DNA circuit

(2014) Jun Liu et al.   ANALYST

Assembly of Multiple DNA Components through Target Binding toward Homogeneous, Isothermally Amplified, and Specific Detection of Proteins

(2014) Bin Deng et al.   ANALYTICAL CHEMISTRY

Proximity Ligation Assay with Three-Way Junction-Induced Rolling Circle Amplification for Ultrasensitive Electronic Monitoring of Concanavalin A

(2014) Bingqian Liu et al.   ANALYTICAL CHEMISTRY

Proximity Hybridization Regulated DNA Biogate for Sensitive Electrochemical Immunoassay

(2014) Kewei Ren et al.   ANALYTICAL CHEMISTRY

Glucose Oxidase-Catalyzed Growth of Gold Nanoparticles Enables Quantitative Detection of Attomolar Cancer Biomarkers

(2014) Dingbin Liu et al.   ANALYTICAL CHEMISTRY

Proximity Hybridization-Triggered Signal Switch for Homogeneous Chemiluminescent Bioanalysis

(2014) Chen Zong et al.   ANALYTICAL CHEMISTRY

Aptamers Facilitating Amplified Detection of Biomolecules

(2014) Feng Li et al.   ANALYTICAL CHEMISTRY

Digital, Ultrasensitive, End-Point Protein Measurements with Large Dynamic Range via Brownian Trapping with Drift

(2014) Shencheng Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Reusable Electrochemical Proximity Assay for Highly Selective, Real-Time Protein Quantitation in Biological Matrices

(2014) Jiaming Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plasmonic ELISA for the detection of gp120 at ultralow concentrations with the naked eye

(2014) D. Cecchin et al.   Nanoscale

Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering

(2014) Shana O. Kelley et al.   Nature Nanotechnology

Digital microfluidic assay for protein detection

(2014) Janine Mok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection

(2014) Dong-Ku Kang et al.   Nature Communications

Gold Nanoparticle-Based Activatable Probe for Sensing Ultralow Levels of Prostate-Specific Antigen

(2013) Dingbin Liu et al.   ACS Nano

Ultrarapid Generation of Femtoliter Microfluidic Droplets for Single-Molecule-Counting Immunoassays

(2013) Jung-uk Shim et al.   ACS Nano

Nanomaterials for Ultrasensitive Protein Detection

(2013) Yi Zhang et al.   ADVANCED MATERIALS

Western Blotting Using Microchip Electrophoresis Interfaced to a Protein Capture Membrane

(2013) Shi Jin et al.   ANALYTICAL CHEMISTRY

Binding-Induced Formation of DNA Three-Way Junctions and Its Application to Protein Detection and DNA Strand Displacement

(2013) Feng Li et al.   ANALYTICAL CHEMISTRY

Acetylcholinesterase-Catalyzed Hydrolysis Allows Ultrasensitive Detection of Pathogens with the Naked Eye

(2013) Dingbin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembling DNA through Affinity Binding to Achieve Ultrasensitive Protein Detection

(2013) Hongquan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic DNA Assemblies Mediated by Binding-Induced DNA Strand Displacement

(2013) Feng Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inductively coupled plasma mass spectrometry-based immunoassay: A review

(2013) Rui Liu et al.   MASS SPECTROMETRY REVIEWS

Yoctomole detection of proteins using solid phase binding-induced DNA assembly

(2013) Hongquan Zhang et al.   METHODS

Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing

(2013) Rachel Yuan Nong et al.   Nature Protocols

Protein-imprinted materials: rational design, application and challenges

(2012) Kaiguang Yang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A Molecular Translator that Acts by Binding-Induced DNA Strand Displacement for a Homogeneous Protein Assay

(2012) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA-Mediated Homogeneous Binding Assays for Nucleic Acids and Proteins

(2012) Hongquan Zhang et al.   CHEMICAL REVIEWS

Quantitation of Femtomolar Protein Levels via Direct Readout with the Electrochemical Proximity Assay

(2012) Jiaming Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plasmonic ELISA for the ultrasensitive detection of disease biomarkers with the naked eye

(2012) Roberto de la Rica et al.   Nature Nanotechnology

Binding-Induced DNA Assembly and Its Application to Yoctomole Detection of Proteins

(2011) Hongquan Zhang et al.   ANALYTICAL CHEMISTRY

Copper-Mediated Amplification Allows Readout of Immunoassays by the Naked Eye

(2011) Weisi Qu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Probing cellular protein complexes using single-molecule pull-down

(2011) Ankur Jain et al.   NATURE

Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood

(2011) Martin Lundberg et al.   NUCLEIC ACIDS RESEARCH

ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing

(2011) Spyros Darmanis et al.   PLoS One

Use of quantum dots in the development of assays for cancer biomarkers

(2010) Megan K. Wagner et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Improvement of Sensitivity and Dynamic Range in Proximity Ligation Assays by Asymmetric Connector Hybridization

(2010) Joonyul Kim et al.   ANALYTICAL CHEMISTRY

Detection ofEscherichia coliO157:H7 Using Gold Nanoparticle Labeling and Inductively Coupled Plasma Mass Spectrometry

(2010) Feng Li et al.   ANALYTICAL CHEMISTRY

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

(2010) David M Rissin et al.   NATURE BIOTECHNOLOGY

Aptamer-Linked Assay for Thrombin Using Gold Nanoparticle Amplification and Inductively Coupled Plasma−Mass Spectrometry Detection

(2009) Qiang Zhao et al.   ANALYTICAL CHEMISTRY

Electrochemical Biosensing Using Amplification-by-Polymerization

(2009) Yafeng Wu et al.   ANALYTICAL CHEMISTRY

Fluorescence Signal Amplification by Cation Exchange in Ionic Nanocrystals

(2009) Jishan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Drivers of biodiagnostic development

(2009) David A. Giljohann et al.   NATURE

Quantum Dot Self-Assembly for Protein Detection with Sub-Picomolar Sensitivity

(2008) Chinmay P. Soman et al.   LANGMUIR