Surface plasmon resonance biosensors for simultaneous monitoring of amyloid-beta oligomers and fibrils and screening of select modulators

Concept for Simultaneous and Specific in Situ Monitoring of Amyloid Oligomers and Fibrils via Förster Resonance Energy Transfer

(2014) Bruno Alies et al.   ANALYTICAL CHEMISTRY

Electrochemical Immunosensors for Effective Evaluation of Amyloid-Beta Modulators on Oligomeric and Fibrillar Aggregation Processes

(2014) Anthony J. Veloso et al.   ANALYTICAL CHEMISTRY

Surface Plasmon Resonance Imaging of Amyloid-β Aggregation Kinetics in the Presence of Epigallocatechin Gallate and Metals

(2013) Xin R. Cheng et al.   ANALYTICAL CHEMISTRY

Sensitive and Continuous Screening of Inhibitors of β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) at Single SPR Chips

(2013) Xinyao Yi et al.   ANALYTICAL CHEMISTRY

Real-time probing of β-amyloid self-assembly and inhibition using fluorescence self-quenching between neighbouring dyes

(2013) Steven D. Quinn et al.   Molecular BioSystems

Dye-Binding Assays for Evaluation of the Effects of Small Molecule Inhibitors on Amyloid (Aβ) Self-Assembly

(2012) Laramie P. Jameson et al.   ACS Chemical Neuroscience

Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

(2011) Jiyong Lee et al.   Nature Chemical Biology

Interface design and multiplexed analysis with surface plasmon resonance (SPR) spectroscopy and SPR imaging

(2010) Matthew J. Linman et al.   ANALYST

Label-Free High-Throughput Screening Assay for Inhibitors of Alzheimer’s Amyloid-β Peptide Aggregation Based on MALDI MS

(2010) Kairit Zovo et al.   ANALYTICAL CHEMISTRY

Regenerable and Simultaneous Surface Plasmon Resonance Detection of Aβ(1−40) and Aβ(1−42) Peptides in Cerebrospinal Fluids with Signal Amplification by Streptavidin Conjugated to an N-Terminus-Specific Antibody

(2010) Ning Xia et al.   ANALYTICAL CHEMISTRY

Calorimetry as a tool for understanding biomolecular interactions and an aid to drug design

(2010) John E. Ladbury   BIOCHEMICAL SOCIETY TRANSACTIONS

Generation and Therapeutic Efficacy of Highly Oligomer-Specific  -Amyloid Antibodies

(2010) H. Hillen et al.   JOURNAL OF NEUROSCIENCE

Measurement of anti-Aβ1–42 antibodies in intravenous immunoglobulin with indirect ELISA: The problem of nonspecific binding

(2010) Andrea C. Klaver et al.   JOURNAL OF NEUROSCIENCE METHODS

Methylene blue and Alzheimer's disease

(2009) Murat Oz et al.   BIOCHEMICAL PHARMACOLOGY

Surface Plasmon Resonance Analysis of Alzheimer's β-Amyloid Aggregation on a Solid Surface:  From Monomers to Fully-Grown Fibrils

(2008) Jungki Ryu et al.   ANALYTICAL CHEMISTRY

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

Rifampicin Does Not Prevent Amyloid Fibril Formation by Human Islet Amyloid Polypeptide but Does Inhibit Fibril Thioflavin-T Interactions: Implications for Mechanistic Studies of β-Cell Death†

(2008) Fanling Meng et al.   BIOCHEMISTRY

Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species

(2008) Jiří Homola   CHEMICAL REVIEWS

Small-molecule aggregates inhibit amyloid polymerization

(2008) Brian Y Feng et al.   Nature Chemical Biology