Real-time probing of β-amyloid self-assembly and inhibition using fluorescence self-quenching between neighbouring dyes

Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ

(2013) Kanchan Garai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Rotors: What Lies Behind the High Sensitivity of the Thioflavin-T Fluorescent Marker

(2012) Nadav Amdursky et al.   ACCOUNTS OF CHEMICAL RESEARCH

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

The emerging role of HSP20 as a multifunctional protective agent

(2011) H.V. Edwards et al.   CELLULAR SIGNALLING

Insight into Amyloid Structure Using Chemical Probes

(2011) Ashley A. Reinke et al.   Chemical Biology & Drug Design

A FRET Sensor for Non-Invasive Imaging of Amyloid Formation in Vivo

(2011) Gabriele S. Kaminski Schierle et al.   CHEMPHYSCHEM

Small Molecule Fluorescent Probes for the Detection of Amyloid Self-Assembly In Vitro and In Vivo

(2011) Carlos W. Bertoncini et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red

(2011) Rajesh Mishra et al.   Molecular BioSystems

Specific in situ discrimination of amyloid fibrilsversus α-helical fibres by the fluorophore NIAD-4

(2011) Enrico Brandenburg et al.   Molecular BioSystems

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

(2011) Priyanka Narayan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polymorphism in Alzheimer Aβ Amyloid Organization Reflects Conformational Selection in a Rugged Energy Landscape

(2010) Yifat Miller et al.   CHEMICAL REVIEWS

Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species

(2010) Asad Jan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid structure and assembly: Insights from scanning transmission electron microscopy

(2010) Claire Goldsbury et al.   JOURNAL OF STRUCTURAL BIOLOGY

Highly sensitive amyloid detection enabled by thioflavin T dimers

(2010) Luoheng Qin et al.   Molecular BioSystems

Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research

(2010) Asad Jan et al.   Nature Protocols

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology

Mechanism of amyloid plaque formation suggests an intracellular basis of A  pathogenicity

(2010) R. P. Friedrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

(2009) Sean A. Hudson et al.   FEBS Journal

Towards Multiparametric Fluorescent Imaging of Amyloid Formation: Studies of a YFP Model of α-Synuclein Aggregation

(2009) Tjakko J. van Ham et al.   JOURNAL OF MOLECULAR BIOLOGY

Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function

(2009) L. M. Jungbauer et al.   JOURNAL OF MOLECULAR RECOGNITION

Interprotofilament interactions between Alzheimer's A 1-42 peptides in amyloid fibrils revealed by cryoEM

(2009) R. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Alzheimer A (1-40) and A (1-42) amyloid fibrils reveals similar protofilament structures

(2009) M. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rifampicin Does Not Prevent Amyloid Fibril Formation by Human Islet Amyloid Polypeptide but Does Inhibit Fibril Thioflavin-T Interactions: Implications for Mechanistic Studies of β-Cell Death†

(2008) Fanling Meng et al.   BIOCHEMISTRY

The Fluorescent Amino Acidp-Cyanophenylalanine Provides an Intrinsic Probe of Amyloid Formation

(2008) Peter Marek et al.   CHEMBIOCHEM

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Optical properties of amyloid stained by Congo red: History and mechanisms

(2008) Alexander J. Howie et al.   MICRON

Effect of an amyloidogenic sequence attached to yellow fluorescent protein

(2008) Daizo Hamada et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS