Suppression of tumor growth via IGFBP3 depletion as a potential treatment in glioma

The REMBRANDT study, a large collection of genomic data from brain cancer patients

(2018) Yuriy Gusev et al.   Scientific Data

IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling

(2017) Yong Antican Wang et al.   MOLECULAR CANCER RESEARCH

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Insulin-like growth factor-binding protein-3 inhibits IGF-1-induced proliferation of human hepatocellular carcinoma cells by controlling bFGF and PDGF autocrine/paracrine loops

(2016) Yang Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The challenges associated with molecular targeted therapies for glioblastoma

(2016) Toni Rose Jue et al.   JOURNAL OF NEURO-ONCOLOGY

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

(2015) Jeanette E. Eckel-Passow et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Challenges and the Promise of Molecular Targeted Therapy in Malignant Gliomas

(2015) Hongxiang Wang et al.   NEOPLASIA

STAT-1 expression is regulated by IGFBP-3 in malignant glioma cells and is a strong predictor of poor survival in patients with glioblastoma

(2014) Balaram Thota et al.   JOURNAL OF NEUROSURGERY

Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome

(2013) Arivusudar Marimuthu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

Insulin-like growth factor binding protein-3 (IGFBP-3): Novel ligands mediate unexpected functions

(2013) Robert C. Baxter   Journal of Cell Communication and Signaling

Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression

(2012) Hsiao-Chi Wang et al.   Annals of the New York Academy of Sciences

The role of insulin-like growth factor binding protein-3 in the breast cancer cell response to DNA-damaging agents

(2012) M Z Lin et al.   ONCOGENE

IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments

(2012) S Grkovic et al.   ONCOGENE

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Grade-Specific Expression of Insulin-like Growth Factor-Binding Proteins-2, -3, and -5 in Astrocytomas: IGFBP-3 Emerges as a Strong Predictor of Survival in Patients with Newly Diagnosed Glioblastoma

(2010) V. Santosh et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Potentiation of Growth Factor Signaling by Insulin-like Growth Factor-binding Protein-3 in Breast Epithelial Cells Requires Sphingosine Kinase Activity

(2009) Janet L. Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells

(2009) Brian J. Leibowitz et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prognostic Significance of Growth Factors and the Urokinase-Type Plasminogen Activator System in Pancreatic Ductal Adenocarcinoma

(2009) Aiqun Xue et al.   PANCREAS