Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits

Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency

(2018) Stephanie De Munter et al.   BRAIN PATHOLOGY

Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

(2018) Zhana Haimon et al.   NATURE IMMUNOLOGY

Neuronal Dysfunction and Behavioral Abnormalities Are Evoked by Neural Cells and Aggravated by Inflammatory Microglia in Peroxisomal β-Oxidation Deficiency

(2018) Lien Beckers et al.   Frontiers in Cellular Neuroscience

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential

(2018) Sonia Boulakirba et al.   Scientific Reports

Interleukin-34, a comprehensive review

(2018) Muhammad Baghdadi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A microglial cell model for acyl-CoA oxidase 1 deficiency

(2018) Q. Raas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo

(2017) Sander Beel et al.   HUMAN MOLECULAR GENETICS

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Specific suppression of microgliosis cannot circumvent the severe neuropathology in peroxisomal β-oxidation-deficient mice

(2017) L. Beckers et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

(2017) Tuan Leng Tay et al.   NATURE NEUROSCIENCE

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

(2016) Andrea Crotti et al.   IMMUNITY

Roles of microglia in brain development, tissue maintenance and repair

(2015) Mackenzie A. Michell-Robinson et al.   BRAIN

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency

(2015) Simon Verheijden et al.   GLIA

Next generation sequencing with copy number variant detection expands the phenotypic spectrum of HSD17B4-deficiency

(2014) Daniel S Lieber et al.   BMC Medical Genetics

Sublime Microglia: Expanding Roles for the Guardians of the CNS

(2014) Michael W. Salter et al.   CELL

Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4

(2014) Giovanna Pepe et al.   Journal of Neuroinflammation

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Peroxisomal D-bifunctional protein deficiency: Three adults diagnosed by whole-exome sequencing

(2014) M. A. Lines et al.   NEUROLOGY

Central nervous system pathology in MFP2 deficiency: Insights from general and conditional knockout mouse models

(2013) Simon Verheijden et al.   BIOCHIMIE

Regulation of Microglial Proliferation during Chronic Neurodegeneration

(2013) D. Gomez-Nicola et al.   JOURNAL OF NEUROSCIENCE

Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation

(2013) Simon Verheijden et al.   NEUROBIOLOGY OF DISEASE

The function of BDNF in the adult auditory system

(2013) Wibke Singer et al.   NEUROPHARMACOLOGY

Microglia, seen from the CX3CR1 angle

(2013) Yochai Wolf et al.   Frontiers in Cellular Neuroscience

Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo

(2012) Ying Li et al.   DEVELOPMENTAL CELL

Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

(2012) Melanie Greter et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system

(2012) Astrid Bottelbergs et al.   Journal of Neuroinflammation

The yin-yang nature of CSF1R-binding cytokines

(2012) Teresa Zelante et al.   NATURE IMMUNOLOGY

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

(2011) Tetsuya Mizuno et al.   AMERICAN JOURNAL OF PATHOLOGY

Mutations in the DBP-Deficiency Protein HSD17B4 Cause Ovarian Dysgenesis, Hearing Loss, and Ataxia of Perrault Syndrome

(2010) Sarah B. Pierce et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

(2010) Suwen Wei et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism

(2010) Paul P. Van Veldhoven   JOURNAL OF LIPID RESEARCH

Neurodegeneration in D-bifunctional protein deficiency: diagnostic clues and natural history using serial magnetic resonance imaging

(2010) Aneal Khan et al.   NEURORADIOLOGY

Microglia and neuroprotection: From in vitro studies to therapeutic applications

(2010) Elisabetta Polazzi et al.   PROGRESS IN NEUROBIOLOGY

Absence of Functional Peroxisomes from Mouse CNS Causes Dysmyelination and Axon Degeneration

(2008) L. Hulshagen et al.   JOURNAL OF NEUROSCIENCE

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING