AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression

Electroacupuncture inhibits NLRP3 inflammasome activation through CB2 receptors in inflammatory pain

(2018) Fang Gao et al.   BRAIN BEHAVIOR AND IMMUNITY

κ-opioid receptor activation protects against myocardial ischemia-reperfusion injury via AMPK/Akt/eNOS signaling activation

(2018) Shumiao Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Methyl cinnamate alleviated CCI-induced upregualtion of spinal AMPA receptors and pain hypersensitivity by targeting AMPK

(2018) Yulong Gui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain

(2018) Xiao-Cen Fan et al.   Frontiers in Molecular Neuroscience

Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling

(2018) Sidra Khalid et al.   Frontiers in Pharmacology

Association between IL-1β + 3954C/T polymorphism and myocardial infarction risk

(2018) Yizhen Fang et al.   MEDICINE

Bee Venom and Hesperidin Effectively Mitigate Complete Freund’s Adjuvant-Induced Arthritis Via Immunomodulation and Enhancement of Antioxidant Defense System

(2018) Osama Ahmed   Archives of Rheumatology

The inhibition of spinal synaptic plasticity mediated by activation of AMP-activated protein kinase signaling alleviates the acute pain induced by oxaliplatin

(2017) Yun-Zhi Ling et al.   EXPERIMENTAL NEUROLOGY

Interleukin-1 receptor type 1 is overexpressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant-induced inflammatory pain

(2017) Krisztina Holló et al.   Journal of Neuroinflammation

Deletion of Type-2 Cannabinoid Receptor Induces Alzheimer’s Disease-Like Tau Pathology and Memory Impairment Through AMPK/GSK3β Pathway

(2017) Lin Wang et al.   MOLECULAR NEUROBIOLOGY

Slowly Signaling G Protein–Biased CB2Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence

(2017) Xiaoyan Lin et al.   MOLECULAR PHARMACOLOGY

PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1

(2017) Gang Chen et al.   NATURE NEUROSCIENCE

AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids

(2017) Tanya S. King-Himmelreich et al.   NEUROPHARMACOLOGY

Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice

(2017) Michael D. Burton et al.   NEUROSCIENCE

Tetrandrine suppresses articular inflammatory response by inhibiting pro-inflammatory factors via NF-κB inactivation

(2016) Li-Na Gao et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Probucol inhibits neural cell apoptosis via inhibition of mTOR signaling pathway after spinal cord injury

(2016) Zipeng Zhou et al.   NEUROSCIENCE

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

(2016) Tarsis F. Brust et al.   Science Signaling

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

(2016) Tarsis F. Brust et al.   Science Signaling

Anti-inflammatory effect of AMPK signaling pathway in rat model of diabetic neuropathy

(2016) Amin Hasanvand et al.   INFLAMMOPHARMACOLOGY

TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation

(2016) Xing-Jun Liu et al.   Scientific Reports

Involvement of AMPK, IKβα-NFκB and eNOS in the sildenafil anti-inflammatory mechanism in a demyelination model

(2015) Ana Karolina Santana Nunes et al.   BRAIN RESEARCH

Involvement of AMPK/SIRT1 pathway in anti-allodynic effect of troxerutin in CCI-induced neuropathic pain

(2015) Yulong Gui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

IL-1β Is Involved with the Generation of Pain in Experimental Autoimmune Encephalomyelitis

(2015) David Henrique Rodrigues et al.   MOLECULAR NEUROBIOLOGY

AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

(2015) Monica Guma et al.   PLoS One

GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages and enhances severity of acute lung injury

(2014) Dae Won Park et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

(2014) Elisa Mazzini et al.   IMMUNITY

Endogenous Interleukin-1β in Neuropathic Rats Enhances Glutamate Release from the Primary Afferents in the Spinal Dorsal Horn through Coupling with PresynapticN-Methyl-d-aspartic Acid Receptors

(2013) Xisheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Tephrosia sinapouethyl acetate extract inhibits inflammatory pain in mice: Opioid receptor dependent inhibition of TNFαand IL-1βproduction

(2013) Renata M. Martinez et al.   PHARMACEUTICAL BIOLOGY

Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity

(2013) Yiming Zhou et al.   Nature Communications

AMP-activated protein kinase: new regulation, new roles?

(2012) David Carling et al.   BIOCHEMICAL JOURNAL

Elevated IL-1β and IL-6 levels in lumbar herniated discs in patients with sciatic pain

(2012) Pablo Andrade et al.   EUROPEAN SPINE JOURNAL

Electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid CB2 receptors

(2011) T.-F. Su et al.   EUROPEAN JOURNAL OF PAIN

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

Caspase-1 is Involved in the Genesis of Inflammatory Hypernociception by Contributing to Peripheral IL-1β Maturation

(2010) Thiago M Cunha et al.   Molecular Pain

Berberine suppresses proinflammatory responses through AMPK activation in macrophages

(2009) Hyun Woo Jeong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

PPARα activators upregulate eNOS activity and inhibit cytokine-induced NF-κB activation through AMP-activated protein kinase activation

(2008) Toshie Okayasu et al.   LIFE SCIENCES