Tyrosine hydroxylase phosphorylation in vivo

The effects of recurrent hypoglycaemia and opioid antagonists on the adrenal catecholamine synthetic capacity in a rat model of HAAF

(2018) Manjula Senthilkumaran et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Human tyrosine hydroxylase in Parkinson’s disease and in related disorders

(2018) Toshiharu Nagatsu et al.   JOURNAL OF NEURAL TRANSMISSION

Tyrosine hydroxylase as a sentinel for central and peripheral tissue responses in Parkinson’s progression: Evidence from clinical studies and neurotoxin models

(2018) M.E. Johnson et al.   PROGRESS IN NEUROBIOLOGY

Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules

(2017) Ana Jorge-Finnigan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peripheral Lipopolysaccharide Challenge Induces Long-Term Changes in Tyrosine Hydroxylase Regulation in the Adrenal Medulla

(2017) Lin Kooi Ong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Dissociation of Striatal Dopamine and Tyrosine Hydroxylase Expression from Aging-Related Motor Decline: Evidence from Calorie Restriction Intervention

(2017) Michael F Salvatore et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons

(2017) Lin Kooi Ong et al.   Scientific Reports

Regulation of Tyrosine Hydroxylase Expression and Phosphorylation in Dopamine Transporter-Deficient Mice

(2016) Michael F. Salvatore et al.   ACS Chemical Neuroscience

Inhibition of deubiquitinating activity of USP14 decreases tyrosine hydroxylase phosphorylated at Ser19 in PC12D cells

(2016) Akira Nakashima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Molecular Chaperone Hsc70 Interacts with Tyrosine Hydroxylase to Regulate Enzyme Activity and Synaptic Vesicle Localization

(2016) Leonardo A. Parra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome-mediated degradation of tyrosine hydroxylase triggered by its phosphorylation: a new question as to the intracellular location at which the degradation occurs

(2016) Akira Nakashima et al.   JOURNAL OF NEURAL TRANSMISSION

Interleukin-6-mediated signaling in adrenal medullary chromaffin cells

(2016) Danielle E. Jenkins et al.   JOURNAL OF NEUROCHEMISTRY

Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese

(2016) Tanara V. Peres et al.   Metallomics

The Effects of Insulin-Induced Hypoglycaemia on Tyrosine Hydroxylase Phosphorylation in Rat Brain and Adrenal Gland

(2016) Manjula Senthilkumaran et al.   NEUROCHEMICAL RESEARCH

Dopamine or biopterin deficiency potentiates phosphorylation at 40 Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system

(2015) Ichiro Kawahata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of protein kinase (PK) Cδattenuates methamphetamine-induced dopaminergic toxicity via upregulation of phosphorylation of tyrosine hydroxylase at Ser40by modulation of protein phosphatase 2A and PKA

(2015) Duy-Khanh Dang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Protein Phosphatase 2A is Involved in the Tyrosine Hydroxylase Phosphorylation Regulated by α-Synuclein

(2015) Gao Hua et al.   NEUROCHEMICAL RESEARCH

IRBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation

(2015) Katsuhiro Kawaai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine Hydroxylase Is Short-Term Regulated by the Ubiquitin-Proteasome System in PC12 Cells and Hypothalamic and Brainstem Neurons from Spontaneously Hypertensive Rats: Possible Implications in Hypertension

(2015) Nadia A. Longo Carbajosa et al.   PLoS One

ser31 tyrosine hydroxylase phosphorylation parallels differences in dopamine recovery in nigrostriatal pathway following 6-OHDA lesion

(2014) Michael F. Salvatore   JOURNAL OF NEUROCHEMISTRY

Neurobiological consequences of acute footshock stress: effects on tyrosine hydroxylase phosphorylation and activation in the rat brain and adrenal medulla

(2013) Lin Kooi Ong et al.   JOURNAL OF NEUROCHEMISTRY

Early Life Stress and Post-Weaning High Fat Diet Alter Tyrosine Hydroxylase Regulation and AT1 Receptor Expression in the Adrenal Gland in a Sex Dependent Manner

(2013) Larisa Bobrovskaya et al.   NEUROCHEMICAL RESEARCH

Functional Programming of the Autonomic Nervous System by Early Life Immune Exposure: Implications for Anxiety

(2013) Luba Sominsky et al.   PLoS One

Redox Sensitivity of Tyrosine Hydroxylase Activity and Expression in Dopaminergic Dysfunction

(2012) Giuseppe Di Giovanni et al.   CNS & Neurological Disorders-Drug Targets

A Brief Overview of Tyrosine Hydroxylase and α-Synuclein in the Parkinsonian Brain

(2012) Wajihullah Khan et al.   CNS & Neurological Disorders-Drug Targets

Tyrosine Hydroxylase Gene: Another Piece of the Genetic Puzzle of Parkinson’s Disease

(2012) Guney Bademci et al.   CNS & Neurological Disorders-Drug Targets

Moving Beyond Tyrosine Hydroxylase to Define Dopaminergic Neurons for Use in Cell Replacement Therapies for Parkinson’s Disease

(2012) Robert B. White et al.   CNS & Neurological Disorders-Drug Targets

A Synopsis on the Role of Tyrosine Hydroxylase in Parkinson’s Disease

(2012) Shams Tabrez et al.   CNS & Neurological Disorders-Drug Targets

Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser19

(2012) Michael F. Salvatore et al.   EXPERIMENTAL NEUROLOGY

The Sustained Phase of Tyrosine Hydroxylase Activation In vivo

(2012) Lin Kooi Ong et al.   NEUROCHEMICAL RESEARCH

Dichotomy of Tyrosine Hydroxylase and Dopamine Regulation between Somatodendritic and Terminal Field Areas of Nigrostriatal and Mesoaccumbens Pathways

(2012) Michael F. Salvatore et al.   PLoS One

Tyrosine Hydroxylase Phosphorylation in Catecholaminergic Brain Regions: A Marker of Activation following Acute Hypotension and Glucoprivation

(2012) Hanafi A. Damanhuri et al.   PLoS One

Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme

(2011) Akira Nakashima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mutational Analysis of Catecholamine Binding in Tyrosine Hydroxylase

(2011) Gabrielle D. Briggs et al.   BIOCHEMISTRY

Epigenetic, transcriptional and posttranscriptional regulation of the tyrosine hydroxylase gene

(2011) Robert Lenartowski et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

PKCδ inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment

(2011) Eun-Joo Shin et al.   NEUROCHEMISTRY INTERNATIONAL

The effects of footshock and immobilization stress on tyrosine hydroxylase phosphorylation in the rat locus coeruleus and adrenal gland

(2011) L.K. Ong et al.   NEUROSCIENCE

Biphasic dopamine regulation in mesoaccumbens pathway in response to non-contingent binge and escalating methamphetamine regimens in the Wistar rat

(2011) Courtney M. Keller et al.   PSYCHOPHARMACOLOGY

Effects of manganese on tyrosine hydroxylase (TH) activity and TH-phosphorylation in a dopaminergic neural cell line

(2011) Danhui Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tyrosine hydroxylase and regulation of dopamine synthesis

(2010) S. Colette Daubner et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

CRF2 mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats

(2010) Javier Navarro-Zaragoza et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function

(2010) Kathryn A. Skelding et al.   CELLULAR SIGNALLING

Serine 129 Phosphorylation Reduces the Ability of α-Synuclein to Regulate Tyrosine Hydroxylase and Protein Phosphatase 2Ain Vitroandin Vivo

(2010) Haiyan Lou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinic Stimulation of Catecholamine Synthesis and Tyrosine Hydroxylase Phosphorylation in Cervine Adrenal Medullary Chromaffin Cells

(2010) P. J. Knowles et al.   JOURNAL OF NEUROENDOCRINOLOGY

Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Regulation of Dopaminergic Neural Transmission by Tyrosine Hydroxylase Protein at Nerve Terminals

(2010) Chiho Sumi-Ichinose et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use–dependent inhibitor of dopamine synthesis

(2010) Lina Yao et al.   NATURE MEDICINE

The Effect of Social Defeat on Tyrosine Hydroxylase Phosphorylation in the Rat Brain and Adrenal Gland

(2010) Lin Kooi Ong et al.   NEUROCHEMICAL RESEARCH

Signal transduction pathways and tyrosine hydroxylase regulation in the adrenal medulla following glucoprivation: An in vivo analysis

(2010) Larisa Bobrovskaya et al.   NEUROCHEMISTRY INTERNATIONAL

Phosphorylation of α-synuclein upregulates tyrosine hydroxylase activity in MN9D cells

(2009) Bo Wu et al.   ACTA HISTOCHEMICA

Pattern-Specific Sustained Activation of Tyrosine Hydroxylase by Intermittent Hypoxia: Role of Reactive Oxygen Species-Dependent Downregulation of Protein Phosphatase 2A and Upregulation of Protein Kinases

(2009) Gayatri Raghuraman et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular Determinants for PP2A Substrate Specificity: Charged Residues Mediate Dephosphorylation of Tyrosine Hydroxylase by the PP2A/B′ Regulatory Subunit

(2009) Amit Saraf et al.   BIOCHEMISTRY

Differential regulation of human tyrosine hydroxylase isoforms 1 and 2 in situ: Isoform 2 is not phosphorylated at Ser35

(2009) Sarah L. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome

(2009) J. R. Connor et al.   BRAIN

Elevated Glucocorticoid Levels Are Responsible for Induction of Tyrosine Hydroxylase mRNA Expression, Phosphorylation, and Enzyme Activity in the Nucleus of the Solitary Tract during Morphine Withdrawal

(2009) Cristina Núñez et al.   ENDOCRINOLOGY

Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system

(2009) Michael F. Salvatore et al.   EXPERIMENTAL NEUROLOGY

Three-way Interaction between 14-3-3 Proteins, the N-terminal Region of Tyrosine Hydroxylase, and Negatively Charged Membranes

(2009) Øyvind Halskau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

14-3-3ζ Contributes to Tyrosine Hydroxylase Activity in MN9D Cells

(2009) Jian Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Biochemical and Functional Protein Complex Involving Dopamine Synthesis and Transport into Synaptic Vesicles

(2009) Etienne A. Cartier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Status of DJ-1-dependent Activation of Dopamine Synthesis through Interaction of Tyrosine Hydroxylase and 4-Dihydroxy-l-phenylalanine (l-DOPA) Decarboxylase with DJ-1

(2009) Shizuma Ishikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progesterone decreases tyrosine hydroxylase phosphorylation state and increases protein phosphatase 2A activity in the stalk-median eminence on proestrous afternoon

(2009) Bin Liu et al.   JOURNAL OF ENDOCRINOLOGY

Role of N-terminus of tyrosine hydroxylase in the biosynthesis of catecholamines

(2009) A. Nakashima et al.   JOURNAL OF NEURAL TRANSMISSION

Manganese induces sustained Ser40 phosphorylation and activation of tyrosine hydroxylase in PC12 cells

(2009) Thaís Posser et al.   JOURNAL OF NEUROCHEMISTRY

Effect of Urotensin II on PC12 Rat Pheochromocytoma Cells

(2009) Y. Aita et al.   JOURNAL OF NEUROENDOCRINOLOGY

Cross-Talk between Protein Kinase A and Mitogen-Activated Protein Kinases Signalling in the Adaptive Changes Observed during Morphine Withdrawal in the Heart

(2009) P. Almela et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Low Affinity Dopamine Binding Site on Tyrosine Hydroxylase: The Role of the N-Terminus and In Situ Regulation of Enzyme Activity

(2009) Sarah L. Gordon et al.   NEUROCHEMICAL RESEARCH

Subthalamic stimulation increases striatal tyrosine hydroxylase phosphorylation

(2009) Rene Reese et al.   NEUROREPORT

Aging Reveals a Role for Nigral Tyrosine Hydroxylase ser31 Phosphorylation in Locomotor Activity Generation

(2009) Michael F. Salvatore et al.   PLoS One

Expression of Tyrosine Hydroxylase Increases the Resistance of Human Neuroblastoma Cells to Oxidative Insults

(2009) Jeferson L. Franco et al.   TOXICOLOGICAL SCIENCES

Tyrosine hydroxylase phosphorylation after naloxone-induced morphine withdrawal in the left ventricle

(2008) Pilar Almela et al.   BASIC RESEARCH IN CARDIOLOGY

The 14-3-3 Protein Affects the Conformation of the Regulatory Domain of Human Tyrosine Hydroxylase†

(2008) Veronika Obsilova et al.   BIOCHEMISTRY

The PKs PKA and ERK 1/2 are involved in phosphorylation of TH at Serine 40 and 31 during morphine withdrawal in rat hearts

(2008) P Almela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Direct Binding of GTP Cyclohydrolase and Tyrosine Hydroxylase

(2008) Kevin M. Bowling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment

(2008) Mei Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Silencing α-Synuclein Gene Expression Enhances Tyrosine Hydroxylase Activity in MN9D Cells

(2008) Dongmei Liu et al.   NEUROCHEMICAL RESEARCH

α-Synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: Lessons from viral transduction of knockout mice

(2008) Tshianda N.M. Alerte et al.   NEUROSCIENCE LETTERS

Melatonin inhibits amphetamine-induced increase in α-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK–N–SH cells

(2008) Sirirat Klongpanichapak et al.   NEUROSCIENCE LETTERS

Tyrosine hydroxylase phosphorylation increases in response to ATP and neuropeptide Y co-stimulation of ERK2 phosphorylation

(2008) T LUKE et al.   PHARMACOLOGICAL RESEARCH

Altered Dopamine Signaling in Naturally Occurring Maternal Neglect

(2008) Stephen C. Gammie et al.   PLoS One

Phosphorylation State of Tyrosine Hydroxylase in the Stalk-Median Eminence Is Decreased by Progesterone in Cycling Female Rats

(2007) Bin Liu et al.   ENDOCRINOLOGY

Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ

(2003) Michael F. Salvatore et al.   JOURNAL OF NEUROCHEMISTRY