Neuraminidase inhibition contributes to influenza A virus neutralization by anti-hemagglutinin stem antibodies

Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs

(2018) Ivan Kosik et al.   PLoS Pathogens

In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice

(2017) Troy C. Sutton et al.   JOURNAL OF VIROLOGY

Dissection of Epitope-Specific Mechanisms of Neutralization of Influenza Virus by Intact IgG and Fab Fragments

(2017) James A. Williams et al.   JOURNAL OF VIROLOGY

Influenza A virus hemagglutinin specific antibodies interfere with virion neuraminidase activity via two distinct mechanisms

(2017) Ivan Kosik et al.   VIROLOGY

Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

(2017) Madhusudan Rajendran et al.   mBio

Is It Possible to Develop a “Universal” Influenza Virus Vaccine?

(2017) Florian Krammer et al.   Cold Spring Harbor Perspectives in Biology

Tackling influenza with broadly neutralizing antibodies

(2017) Davide Corti et al.   Current Opinion in Virology

A Broadly Reactive Human Anti-hemagglutinin Stem Monoclonal Antibody That Inhibits Influenza A Virus Particle Release

(2017) Seiya Yamayoshi et al.   EBioMedicine

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes

(2016) Nicole L. Kallewaard et al.   CELL

Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection

(2016) David J. DiLillo et al.   JOURNAL OF CLINICAL INVESTIGATION

Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus

(2016) Wenqian He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

(2016) Caitlin E. Mullarkey et al.   mBio

The human 2B4 and NTB-A receptors bind the influenza viral hemagglutinin and co-stimulate NK cell cytotoxicity

(2016) Alexandra Duev-Cohen et al.   Oncotarget

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids

(2016) Freek Cox et al.   Frontiers in Immunology

Changes in the Length of the Neuraminidase Stalk Region Impact H7N9 Virulence in Mice

(2015) Yuhai Bi et al.   JOURNAL OF VIROLOGY

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Restricted, canonical, stereotyped and convergent immunoglobulin responses

(2015) Carole J. Henry Dunand et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

(2015) A. Impagliazzo et al.   SCIENCE

Flow Cytometry Reveals that H5N1 Vaccination Elicits Cross-Reactive Stem-Directed Antibodies from Multiple Ig Heavy-Chain Lineages

(2014) J. R. R. Whittle et al.   JOURNAL OF VIROLOGY

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection

(2014) V. V. A. Mallajosyula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An In Vivo Human-Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Influenza A Antibodies

(2013) Gerald Nakamura et al.   Cell Host & Microbe

Evolution in the influenza A H3 stalk - a challenge for broad-spectrum vaccines?

(2013) W. D. Lees et al.   JOURNAL OF GENERAL VIROLOGY

Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines

(2013) Y. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies

(2013) A. K. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuraminidase-Mediated, NKp46-Dependent Immune-Evasion Mechanism of Influenza Viruses

(2013) Yotam Bar-On et al.   Cell Reports

Deletions in the Neuraminidase Stalk Region of H2N2 and H9N2 Avian Influenza Virus Subtypes Do Not Affect Postinfluenza Secondary Bacterial Pneumonia

(2012) A. K. Chockalingam et al.   JOURNAL OF VIROLOGY

Amino Acid 316 of Hemagglutinin and the Neuraminidase Stalk Length Influence Virulence of H9N2 Influenza Virus in Chickens and Mice

(2012) Y. Sun et al.   JOURNAL OF VIROLOGY

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

(2012) R. Hai et al.   JOURNAL OF VIROLOGY

Distribution of surface glycoproteins on influenza A virus determined by electron cryotomography

(2012) Sebastian Wasilewski et al.   VACCINE

Emergence and Genetic Variation of Neuraminidase Stalk Deletions in Avian Influenza Viruses

(2011) Jinling Li et al.   PLoS One

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

(2011) D. C. Ekiert et al.   SCIENCE

Structural organization of a filamentous influenza A virus

(2010) L. J. Calder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuraminidase Stalk Length and Additional Glycosylation of the Hemagglutinin Influence the Virulence of Influenza H5N1 Viruses for Mice

(2009) Y. Matsuoka et al.   JOURNAL OF VIROLOGY