A Plasmacytoid Dendritic Cells-Type I Interferon Axis Is Critically Implicated in the Pathogenesis of Systemic Lupus Erythematosus

Type I Interferon-Mediated Skewing of the Serotonin Synthesis Is Associated with Severe Disease in Systemic Lupus Erythematosus

(2015) Christian Lood et al.   PLoS One

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

(2014) Sarah L. Rowland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Potent Induction of IFN-  and Chemokines by Autoantibodies in the Cerebrospinal Fluid of Patients with Neuropsychiatric Lupus

(2014) D. M. Santer et al.   JOURNAL OF IMMUNOLOGY

The Plasmacytoid Dendritic Cell as the Swiss Army Knife of the Immune System: Molecular Regulation of Its Multifaceted Functions

(2014) Julien J. Karrich et al.   JOURNAL OF IMMUNOLOGY

Systemic lupus erythematosus

(2014) Larissa Lisnevskaia et al.   LANCET

The Antiviral Cytokines IFN-α and IFN-β Modulate Parietal Epithelial Cells and Promote Podocyte Loss

(2013) Adriana Migliorini et al.   AMERICAN JOURNAL OF PATHOLOGY

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

(2013) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases

(2013) Jing Li et al.   PHARMACOLOGY & THERAPEUTICS

Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study

(2012) Jacqueline M. McBride et al.   ARTHRITIS AND RHEUMATISM

Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis

(2012) Seth G. Thacker et al.   ARTHRITIS AND RHEUMATISM

Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid

(2012) Bernard R. Lauwerys et al.   ARTHRITIS AND RHEUMATISM

Clinical and serological manifestations associated with interferon-α levels in childhood-onset systemic lupus erythematosus

(2012) M Postal et al.   Clinics

IL-17: A new actor in IFN-driven systemic autoimmune diseases

(2012) Aurélie Ambrosi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Re(de)fining the dendritic cell lineage

(2012) Ansuman T Satpathy et al.   NATURE IMMUNOLOGY

Pathogen sensors and chemokine receptors in dendritic cell subsets

(2012) Tsuneyasu Kaisho   VACCINE

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon   monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

(2011) J. T. Merrill et al.   ANNALS OF THE RHEUMATIC DISEASES

Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice

(2011) Uri Sela et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Interferon-α accelerates murine systemic lupus erythematosus in a T cell-dependent manner

(2010) Zheng Liu et al.   ARTHRITIS AND RHEUMATISM

Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation

(2010) Liat Bar-On et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic Cells in Lupus Are Not Required for Activation of T and B Cells but Promote Their Expansion, Resulting in Tissue Damage

(2010) Lino L. Teichmann et al.   IMMUNITY

Dendritic Cells Support Homeostatic Expansion of Foxp3 + Regulatory T Cells in Foxp3.LuciDTR Mice

(2010) Janine Suffner et al.   JOURNAL OF IMMUNOLOGY

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus

(2010) Ying J Nie et al.   ARTHRITIS RESEARCH & THERAPY

Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus

(2010) Ou Jin et al.   ARTHRITIS RESEARCH & THERAPY

Blood dendritic cells in systemic lupus erythematosus exhibit altered activation state and chemokine receptor function

(2009) V. Gerl et al.   ANNALS OF THE RHEUMATIC DISEASES

Disease activity in systemic lupus erythematosus is associated with an altered expression of low-affinity Fcγ receptors and costimulatory molecules on dendritic cells

(2009) Leandro J. Carreño et al.   IMMUNOLOGY

Dendritic cells require a systemic type I interferon response to mature and induce CD4+Th1 immunity with poly IC as adjuvant

(2009) M. Paula Longhi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

(2009) Agnès Doreau et al.   NATURE IMMUNOLOGY

An overview of IL-17 function and signaling

(2008) Sarah L. Gaffen   CYTOKINE

A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells

(2008) Alexis Vogelzang et al.   IMMUNITY

Severe Systemic Lupus Erythematosus Induced by Antiviral Treatment for Hepatitis C

(2008) Vincent Ho et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dendritic cells in the thymus contribute to T-regulatory cell induction

(2008) A. I. Proietto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunctional interferon-α production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus

(2008) Seung-Ki Kwok et al.   ARTHRITIS RESEARCH & THERAPY

Immature myeloid and plasmacytoid dendritic cells infiltrate renal tubulointerstitium in patients with lupus nephritis

(2007) Nicoletta Fiore et al.   MOLECULAR IMMUNOLOGY