Excitatory pathway engaging glutamate, calcineurin, and NFAT upregulates IL-4 in ischemic neurons to polarize microglia

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke

(2017) Masato Kanazawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulation of different human NFAT isoforms by neuronal activity

(2016) Hanna Vihma et al.   JOURNAL OF NEUROCHEMISTRY

Modeling Ischemic Stroke In Vitro: Status Quo and Future Perspectives

(2016) Paul M. Holloway et al.   STROKE

Interleukin-4 Is Essential for Microglia/Macrophage M2 Polarization and Long-Term Recovery After Cerebral Ischemia

(2016) Xiangrong Liu et al.   STROKE

Neuronal Interleukin-4 as a Modulator of Microglial Pathways and Ischemic Brain Damage

(2015) X. Zhao et al.   JOURNAL OF NEUROSCIENCE

Nuclear Factor of Activated T Cells Regulates the Expression of Interleukin-4 in Th2 Cells in an All-or-none Fashion

(2014) Juliana Köck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-4 Production by T Cells: You Need a Little to Get a Lot

(2014) M. A. Brown   JOURNAL OF IMMUNOLOGY

Mitochondria and NMDA Receptor-Dependent Toxicity of Berberine Sensitizes Neurons to Glutamate and Rotenone Injury

(2014) Kai Kysenius et al.   PLoS One

Neuronal Production of Lipocalin-2 as a Help-Me Signal for Glial Activation

(2014) Changhong Xing et al.   STROKE

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Genetic deletion of CD36 enhances injury after acute neonatal stroke

(2012) Moon-Sook Woo et al.   ANNALS OF NEUROLOGY

IL-4 in the Brain: A Cytokine To Remember

(2012) Sachin P. Gadani et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammation by interleukin-4: a review of “alternatives”

(2012) Irina G. Luzina et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Alternative activation of tumor-associated macrophages by IL-4

(2011) Hao-Wei Wang et al.   CELL CYCLE

Inflammation: Cell Recruitment versus Local Proliferation

(2011) Laura Helming   CURRENT BIOLOGY

Increased Brain Injury and Worsened Neurological Outcome in Interleukin-4 Knockout Mice After Transient Focal Cerebral Ischemia

(2011) Xiaoxing Xiong et al.   STROKE

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

NFAT pulls the strings during CD4+ T helper cell effector functions

(2010) N. Hermann-Kleiter et al.   BLOOD

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY

Regulation of learning and memory by meningeal immunity: a key role for IL-4

(2010) Noël C. Derecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuronal PPAR  Deficiency Increases Susceptibility to Brain Damage after Cerebral Ischemia

(2009) X. Zhao et al.   JOURNAL OF NEUROSCIENCE

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4

(2008) R. F. Fernandez-Boyanapalli et al.   BLOOD

Macrophage diversity in renal injury and repair

(2008) Sharon D. Ricardo et al.   JOURNAL OF CLINICAL INVESTIGATION

The scavenger receptor SR-A I/II (CD204) signals via the receptor tyrosine kinase Mertk during apoptotic cell uptake by murine macrophages

(2008) Jill C. Todt et al.   JOURNAL OF LEUKOCYTE BIOLOGY