Angiogenesis in the ischemic core: A potential treatment target?

Oligodendrogenesis after traumatic brain injury

(2018) Hajime Takase et al.   BEHAVIOURAL BRAIN RESEARCH

Roles of Pericytes in Stroke Pathogenesis

(2018) Jyoti Gautam et al.   CELL TRANSPLANTATION

Microglia and macrophages differ in their inflammatory profile after permanent brain ischemia

(2018) Juan G. Zarruk et al.   EXPERIMENTAL NEUROLOGY

Restorative effects of human neural stem cell grafts on the primate spinal cord

(2018) Ephron S Rosenzweig et al.   NATURE MEDICINE

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

(2018) Gregory W. Albers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke

(2017) Masato Kanazawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

β1-integrin–matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability

(2017) Yoshikane Izawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Vascular expression of angiopoietin1, α5β1 integrin and tight junction proteins is tightly regulated during vascular remodeling in the post-ischemic brain

(2017) Jialan Sun et al.   NEUROSCIENCE

Poststroke Sonic Hedgehog Agonist Treatment Improves Functional Recovery by Enhancing Neurogenesis and Angiogenesis

(2017) Yongming Jin et al.   STROKE

The molecular basis of endothelial cell plasticity

(2017) Elisabetta Dejana et al.   Nature Communications

Integrin α5β1 expression on dopaminergic neurons is involved in dopaminergic neurite outgrowth on striatal neurons

(2017) Yasuhiko Izumi et al.   Scientific Reports

Microglia preconditioned by oxygen-glucose deprivation promote functional recovery in ischemic rats

(2017) Masato Kanazawa et al.   Scientific Reports

Integration of neurogenesis and angiogenesis models for constructing a neurovascular tissue

(2017) Hiroyuki Uwamori et al.   Scientific Reports

Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling

(2016) Stefanie Gurnik et al.   ACTA NEUROPATHOLOGICA

When the endothelium scores an own goal: endothelial cells actively augment metastatic extravasation through endothelial-mesenchymal transition

(2016) Ákos Gasparics et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice

(2016) Karen Gertz et al.   BMC Neurology

Long-term survival and regeneration of neuronal and vasculature cells inside the core region after ischemic stroke in adult mice

(2016) Michael Qize Jiang et al.   BRAIN PATHOLOGY

Cerebral ischemia-induced angiogenesis is dependent on tumor necrosis factor receptor 1-mediated upregulation of α5β1 and αVβ3 integrins

(2016) Heng Huang et al.   Journal of Neuroinflammation

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

Oligodendrocyte precursors migrate along vasculature in the developing nervous system

(2016) H.-H. Tsai et al.   SCIENCE

Endothelial Cells Lining Sporadic Cerebral Cavernous Malformation Cavernomas Undergo Endothelial-to-Mesenchymal Transition

(2016) Luca Bravi et al.   STROKE

Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice

(2015) Dongdong Chen et al.   ASN Neuro

Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke

(2015) Masato Kanazawa et al.   BRAIN

When endothelial cells go rogue

(2015) P.-Y. Chen et al.   EMBO Molecular Medicine

Subcortical ischemic vascular disease: Roles of oligodendrocyte function in experimental models of subcortical white-matter injury

(2015) Akihiro Shindo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Brief Etymology of the Collateral Circulation

(2014) James E. Faber et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke

(2014) Qin Jin et al.   BRAIN BEHAVIOR AND IMMUNITY

Myelin-associated inhibitors in axonal growth after CNS injury

(2014) Cédric G Geoffroy et al.   CURRENT OPINION IN NEUROBIOLOGY

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema after Tissue Plasminogen Activator Treatment for Ischemic Stroke in Rats

(2014) Kunio Kawamura et al.   PLoS One

Stroke Increases Neural Stem Cells and Angiogenesis in the Neurogenic Niche of the Adult Mouse

(2014) Rui Lan Zhang et al.   PLoS One

EndMT contributes to the onset and progression of cerebral cavernous malformations

(2013) Luigi Maddaluno et al.   NATURE

Vascular Endothelial Growth Factor Promotes Pericyte Coverage of Brain Capillaries, Improves Cerebral Blood Flow During Subsequent Focal Cerebral Ischemia, and Preserves the Metabolic Penumbra

(2013) Anil Zechariah et al.   STROKE

Intra-arterial Cell Transplantation Provides Timing-Dependent Cell Distribution and Functional Recovery After Stroke

(2013) Shunsuke Ishizaka et al.   STROKE

Molecular Parallels between Neural and Vascular Development

(2013) A. Eichmann et al.   Cold Spring Harbor Perspectives in Medicine

Laminin/β1 integrin signal triggers axon formation by promoting microtubule assembly and stabilization

(2012) Wen-Liang Lei et al.   CELL RESEARCH

An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia

(2012) Longxuan Li et al.   EXPERIMENTAL NEUROLOGY

Early Loss of Pericytes and Perivascular Stromal Cell-Induced Scar Formation after Stroke

(2012) Francisco Fernández-Klett et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

(2012) Moritz Felcht et al.   JOURNAL OF CLINICAL INVESTIGATION

Concepts and Methods for the Study of Axonal Regeneration in the CNS

(2012) Mark H. Tuszynski et al.   NEURON

Chronic Valproate Treatment Enhances Postischemic Angiogenesis and Promotes Functional Recovery in a Rat Model of Ischemic Stroke

(2012) Zhifei Wang et al.   STROKE

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Intravenous injection of neural progenitor cells facilitates angiogenesis after cerebral ischemia

(2012) Yoshiyuki Moriyama et al.   Brain and Behavior

Upregulation of fibronectin and the α5β1 and αvβ3 integrins on blood vessels within the cerebral ischemic penumbra

(2011) Longxuan Li et al.   EXPERIMENTAL NEUROLOGY

Heterogeneity in the penumbra

(2011) Gregory J del Zoppo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Interendothelial Claudin-5 Expression Depends on Cerebral Endothelial Cell–Matrix Adhesion by β1-Integrins

(2011) Takashi Osada et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of VEGF signaling pathway attenuates hemorrhage after tPA treatment

(2011) Masato Kanazawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

(2011) C. L. Tan et al.   JOURNAL OF NEUROSCIENCE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Granulocyte Colony-Stimulating Factor Enhances Arteriogenesis and Ameliorates Cerebral Damage in a Mouse Model of Ischemic Stroke

(2011) Yukio Sugiyama et al.   STROKE

Mechanisms of arteriogenesis

(2010) W. Cai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The neurovascular unit, matrix proteases, and innate inflammation

(2010) Gregory J. Del Zoppo   Annals of the New York Academy of Sciences

TGF-β Signaling Specifies Axons during Brain Development

(2010) Jason J. Yi et al.   CELL

In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the α6β4 integrin and dystroglycan

(2010) Longxuan Li et al.   GLIA

Characterization and binding activity of the chondroitin/dermatan sulfate chain from Endocan, a soluble endothelial proteoglycan

(2010) S. Sarrazin et al.   GLYCOBIOLOGY

Wide Genetic Variation in the Native Pial Collateral Circulation is a Major Determinant of Variation in Severity of Stroke

(2010) Hua Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Relationship of Neurovascular Elements to Neuron Injury during Ischemia

(2009) Gregory J. del Zoppo   CEREBROVASCULAR DISEASES

Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke

(2009) Ken Arai et al.   FEBS Journal

The neurovascular unit in the setting of stroke

(2009) G. J. del Zoppo   JOURNAL OF INTERNAL MEDICINE

VEGF enhance cortical newborn neurons and their neurite development in adult rat brain after cerebral ischemia

(2009) Yong-Quan Wang et al.   NEUROCHEMISTRY INTERNATIONAL

Increased expression of fibronectin and the α5β1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia

(2008) Richard Milner et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

(2008) G.J. del Zoppo   NEUROSCIENCE